NutritionFacts.org Video Podcast

How Ultra-Processed Foods Could Cause Disease: Packaging Chemicals

6 min
Apr 27, 2026about 1 month ago
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Summary

This episode examines how chemicals from food packaging—including BPA, phthalates, and mineral oils—migrate into ultra-processed foods and accumulate in human tissues, potentially causing disease. The host discusses the regulatory failures that allowed harmful substances like trans fats to remain in the food supply for decades despite known health risks, arguing that the ultra-processed food category itself serves as a useful precautionary framework.

Insights
  • Packaging chemicals pose a significant but largely unlabeled health risk that rivals the nutritional deficiencies of ultra-processed foods themselves
  • Regulatory agencies have consistently failed to act on chemical safety until decades after evidence of harm emerges, resulting in preventable deaths
  • Simple dietary interventions like switching to fresh foods or eating vegetarian for just a few days can reduce chemical exposure by significant margins
  • The food industry's track record of introducing substances later proven harmful justifies a precautionary 'guilty until proven innocent' approach to new food chemicals
  • Phthalate exposure is more strongly associated with minimally processed foods like poultry than ultra-processed foods, complicating simple dietary recommendations
Trends
Growing consumer awareness of packaging-related chemical contamination driving demand for BPA-free and alternative packaging solutionsRegulatory lag in food safety: decades-long delays between scientific evidence of harm and regulatory action on chemicals like trans fats and BPAShift toward precautionary principle in food safety discourse, challenging industry's 'safe until proven harmful' modelIncreased scrutiny of plastic additives and migration, particularly phthalates and bisphenols, in food supply chainsRising interest in fresh and minimally processed foods as a strategy to reduce chemical exposure beyond just nutritional benefitsEmerging focus on mineral oil contamination from recycled paper packaging in food industry sustainability discussionsExpansion of chemical testing methodologies revealing exposure levels in human populations previously thought safeIndustry response through BPA-free labeling and alternative packaging materials as competitive differentiation
People
Dr. Michael Greger
Host and primary speaker analyzing packaging chemicals and ultra-processed food health impacts
Quotes
"Missing from the label are contaminants from processing that I talked about in my last video, as well as contaminants that migrate into the food from the packaging materials."
Dr. Michael Greger
"Have people switch from packaged foods to fresh foods for even just a few days, and evidence of exposure to the measured bisphenols and phthalates based on urine samples drops significantly."
Dr. Michael Greger
"The FDA didn't ban trans fats until more than 25 years after the first solid evidence emerged that increased the risk of heart disease. From the time we knew until the time it was banned, every one of those years, trans fats were killing up to 50,000 Americans each year."
Dr. Michael Greger
"Anytime some chemical comedy comes up with a new preservative, or sweetener, or artificial color, we have no idea how it'll eventually turn out."
Dr. Michael Greger
"Look at its track record. Look at the trail of bodies it's left behind."
Dr. Michael Greger
Full Transcript
Looking at a food label, we can see that many ultra-processed foods are high in salt, sugar, and calories, and low in nutrition, and may contain food additives with questionable safety. Missing from the label are contaminants from processing that I talked about in my last video, as well as contaminants that migrate into the food from the packaging materials. bisphenols like BPA, plastics compounds like phthalates and microplastics, as well as mineral oils. Evidently the mineral oils come from the printing inks from recycled newspapers used in paperboard packaging, which can then migrate into the food and then accumulate in human tissues to levels that have been found to be harmful in a certain strain of rats. But the relevance to humans has been questioned since apparently we can't even extrapolate the results from that strain of rats to another strain of rats. Plastic materials that contact our food may contain thousands of different molecules, in which more than 300 have been considered as potentially risky, including phthalates, which along with bisphenols may have hormone-modulating effects. Have people switch from packaged foods to fresh foods for even just a few days, and evidence of exposure to the measured bisphenols and phthalates based on urine samples drops significantly. The packaging is certainly not limited to ultra foods If we look at the association between the consumption of ultra foods and how many phthalates and bisphenols are flowing through our system researchers found higher levels of 4 and BPF associated with higher consumption of ultra-processed foods. But there was a lack of association with the most common ones, DEHP and BPA, and an inverse association for BPS, meaning the more ultra-processed ones die, the lower the exposure. This makes sense, since in the food supply, BPS has only been found in meat, most of which is considered minimally processed, with two exceptions. Basically, with BPA, which is used to line cans, only about half these products are ultra-processed compared to moderately processed. In terms of phthalates in our diet, the highest levels of DHP per serving were found in poultry. So if we look at dietary intake and phthalate body burden, DHP levels were associated with the consumption of poultry, presumably most of which was minimally processed. That helps explain why eating vegetarian for a few days can also lead to significant decreases in phthalate exposure, though presumably they also cut down on ultra-processed foods during that time. Although phthalates are best known as hormone disruptors with potential testicular toxicity, ovarian toxicity, and endometriosis, there's also concern about kidney toxicity, nerve damage, liver damage, and heart damage. Exposure to BPA the best studied bisphenol is associated with congenital abnormalities diabetes polycystic ovary syndrome obesity and cardiovascular disease At first we didn think the migration of BPA into foods was high enough to exceed safety levels but then oopsie we realized there is significant evidence of potential harm from levels of BPAs in food well below current regulations and well below levels consumers have been regularly exposed to. Yet, we continue to produce millions of tons of the stuff, so it's no surprise that nearly 90% of us have trace levels of the stuff flowing through us on a day-to-day basis. But it depends on what we eat. Randomized people eat a serving of canned soup every day for five days and see a thousand percent rise in BPA levels compared to eating soup every day made from fresh ingredients. In this case, the soup was ultra-processed, but it's more about what the cans were lined with. Here's a non-exhaustive list of brands that do not use BPA in their canned goods. So yes, we can look for BPA-free on the label, just like we can check labels to see if some ultra-processed product is low in added sugar, salt, and saturated fat, and we can also scan the ingredients list for additives we now know may be harmful. But do you see the problem? Many were considered harmless until they weren't, like the BPA and aspartame stories. and artificial colors and flavors that were in the food supply for decades before they were banned? Remember when the food industry thought partially hydrogenated oils were a good idea Let replace saturated fats with trans fats Although many countries now restrict their use trans fats may continue to kill up to half a million people around the world each year Of course excess saturated fat is probably also killing hundreds of thousands a year But the point is that trans fats from partially hydrogated vegetable oil killed people for decades before there were any limits on it. The FDA didn't ban trans fats until more than 25 years after the first solid evidence emerged that increased the risk of heart disease. From the time we knew until the time it was banned, every one of those years, trans fats were killing up to 50,000 Americans each year. That's quite the death toll that can be laid at the feet of the ultra-processed food industry. But they originally thought it was safe. That's the problem. Anytime some chemical comedy comes up with a new preservative, or sweetener, or artificial color, We have no idea how it'll eventually turn out. So you can start to see the value of this ultra-processed food concept, where an entire category of products is essentially presumed guilty until proven innocent. That drives the food industry crazy, but look at its track record. Look at the trail of bodies it's left behind. I'm going to Liverpool FC V OK?