Jess Kane (BodyBio): How Omega Ratios, Low Fat Diets, and Damaged Cell Membranes Trigger Skin Aging

Welcome to the Biohacking Beauty Podcast, where we explore skin aging through the lens of cellular science and regenerative biology. I am Anastasia Hojaeva. I am Amitai Eshel. We are the founders of... Yangus Skincare and the hosts of Biohacking Beauty Podcast. the podcast that makes sense of longevity science and applies it to your your pursuit yeah in looking your best correct and today we are joined by jess kane co-owner and chief marketing officer of body biome to unpack the connection between visible skin aging advanced skincare and internal cellular health in this episode we dive into why even the most cutting edge skincare and red light therapy fall short without the right cellular building blocks. We talk about how cellular membrane health directly shapes the way we age, why omega fats are so widely misunderstood, and why most liposomal supplements never actually make it into the cell. If you've ever wondered why advanced skincare treatments aren't delivering the results you expected and you know what can you do internally to support real lasting change this conversation is for you welcome to the biohacking beauty podcast thank you for having me actually i want to start it's a little bit off the this but did you hear that uh dr parricone which is like um old school old school but good school i mean respect dr parricone huge like conventional kind of Sephora skincare brand. Yeah. He's going to write a book about phosphatidylcholine. Really? And that it is a longevity molecule. Yeah. I don't know when it's going to be out. Stop. But he told us that. Yeah. In confidence, he said, don't tell anyone. No, I'm kidding. He said it on stage. I got to reach out to him. Yeah, yeah, yeah. Interesting. I mean, it is, I think it's the best longevity molecule. I just think that it's not sexy, right? It's biology. It's like basic biochemistry. It's too PC to be sexy. That's it. It's what? It's too PC to be sexy. Exactly. Yeah. Well, I think on that note, we can kind of talk a little bit about the fact that right now a modern woman, you know, it seems like she's doing everything. You know, she's doing her regular facials. She got her red light therapy in her skin care. And yet, you know, she still battles like all of the signs of aging. You know, everyone does. Right. Like she's still concerned about her skin being dry and having the lines. And you're coming from a different perspective. And like, what is, do you think, is she missing anything from within? Could it be that, you know, she's only doing the superficial approach and it can only get you so far? But I think that's not the answer. I really think so. And I think in today's world, we're trying to do everything. I mean, for me personally, I try to do everything as natural as possible. With active. I'm not a crazy, I don't have to look at it from the perspective of every single ingredient needs to be something natural. I'm not putting beef towel on my face. Good. Now we can be friends. Yeah, exactly, right? I'm not doing a ton of injectables and things like that, and I'm looking for the most natural approaches to aging. I want to age and look good. I don't want to look crazy. I just want to look healthy. And I think in today's world, we're doing all of these things, but we're not thinking enough about the actual building blocks of our skin and the scaffolding and what holds it together. And I think that we need to just start thinking about that more because I think that the low-fat era of the 1980s is so pervasive and has stuck around for so long that we are eating less fat than ever. Well, probably not as little as we were in the 1990s and the 2000s, but we still think that fat is olive oil and avocados and that's not the that's not what makes up our skin i think more than that i mean first of all you're correct and uh as human beings as we say quite often here human beings are really not well built to measure incremental change or to feel or to intuit incremental incremental change if it was so as i often say mcdonald's would have been out of business. But it is also true to say that our body within seven years is almost is rebuilt anew every seven years, you know, depends on the on the cell. But we're basically whatever we're putting in is going to be part of the makeup of ourselves, etc. as time goes on. So the although we're used to thinking of I'm going to wait until I'm fit, you know, fit in the blank to get plastic surgery. I'm going once every three months to do this laser. I'm going to do once a month this and And the reality is that those micro decisions of what am I supplementing on, whether it is with food or with supplements or whatever that is, on a regular basis, these small inputs are the ones that are going to quite literally be our body within whether it's skin cells going to be a month, your mitochondria is going to be two weeks, etc., etc. Yeah, and that's reflective in our skin. Our skin is our largest organ. So if you're taking care of your body from within, you're taking care of each of those cells. Those cells make up those various different organs and your skin is your largest organ. Well, you often say that, well, I hear you say that the cell membranes is the foundation of skin health. And can you like expand on that? Can you, you know, address how it affects the skin barrier? Yeah, it's really fascinating. So phospholipids are, and phosphatidylcholine is what makes up the bubble that protects each of our cells. There's, in women, 32 trillion cells. In men, they estimate it's about 40 trillion cells. Each of these cells has a barrier that protects the cell. The world, oxidative stress, toxins, all of these things break down that cell barrier and that cell bubble that's protecting the cell. So you're constantly making phospholipids and you're constantly losing phospholipids. I think we're probably losing them at a higher rate in today's world. We also tend to lose them as we get older. You have less ability to actually synthesize them from foods. So what's really interesting about the skin and the outer layer of the skin is phospholipids essentially act as like the cement between bricks. It's what holds everything together. And when you don't have enough of it, you're going to see it in your skin quality, in your skin tone, in texture, in skin laxity. And so it's just really critical, these bioactive lipids like phosphatidylcholine, omega-3, omega-6, these essential fatty acids, for the fluidity and the balance in our skin. Yeah. And actually, first of all, I want to say that I'm obsessed with your PC. Like, I'm obsessed. I have like a year worth of stock because I never want to run out. There is someone that's even significantly more obsessed than you. Yes, actually. Significantly. I'm talking about like your baby. Yeah. Ever since I chatted with you and you said that we can give it to our baby, like, you know one year old and we started giving to him at one years old and he loves it my kids too he actually is calling it yum yum yeah that is called yum yum and and uh he's asking for more like every time we give him like a half of a teaspoon he's actually asking for more i mean i literally pour it directly in my kids mouths they're like little birds they just i said it's brain meddy time and they all just go my and my youngest always asks for more and i think that they need they know what they need of course they're also going to ask for sure if they know what they need then he really needs watermelon like probably yeah but but it was it's so amazing to me and um yeah i've been recommending it to my mom friends and and i don't want to brag it's really hard not to brag but our kids uh already at this age like speak some three languages and you know sometimes we're at parties and people are like what's your secret i'm like we don't really have a secret but but we do give them just the one supplement and you know this is what it is so i already have a couple of mom friends i love it uh on it as well yeah but yeah so i'm personally obsessed and i can see it uh on my skin sometimes if i travel i don't take it with me and anyway travel tends to dehydrate our skin and you don't look your best after traveling but i can actually attest that when i take the pc i um like i my skin looks plumpier and juicier and so i i've said it on this podcast before i've like shared those on instagram like it's my non-negotiable, but you mentioned something about omega-6s and omega-3s. And I feel like there is so much misinformation and people are just like, they're only talking about omega-3s and they sometimes don't understand that there should be a specific ratio between the two. Yeah. So can you like educate us a little bit on that? People assume that all of us are eating too many oxidized omega-6s and that's the whole seed oil debate. But the reality is our cells, our cell membrane needs a ratio of four parts, six to one part three. So slamming fish oil is not the answer because that's the one part. That's the omega-3. And you don't need that much fish oil. Eating fresh fish is a great way to get fish. Caviar is actually the best way to get whole, really good quality fish. So that's a good one. That's already in a phospholipid form. Exactly. But the sixth debate is really interesting because a lot of people say, well, we eat too much processed foods. But if you are someone who is already health conscious and you are not eating processed foods every day, you're not eating McDonald's or Chick-fil-A, and you're not frying everything in canola oil in your home, you need unoxidized 6s. And they provide that bounce and that fluidity. The bounce that we get to our skin is part of the essential fatty acid matrix that works in conjunction with phospholipids in the bilipid layer. So there's cholesterol in there, and there's proteins, and there's the electron transport chains. There's all sorts of wonderful little things that happen on the cell membrane, but the majority of it is made up of essential fatty acids and phospholipids. And that's sort of the approach you took with the balancing oil, right? Is that the one? The 4 to 1 ratio, right? Exactly. And this is from research. Actually, interestingly enough, it was many Israeli researchers in the 1980s who really determined that that was the ratio in the cell membrane. And so it has always been an organic, cold press, very carefully treated. We recommend people refrigerate it. But the one thing I constantly here because I'll often tell my friends, they'll say, I want to get started on body bio, which should I take? Start with foundational PC balanced oil butyrate. And within one month, they're writing to me going, why does my skin look so good? Why do I feel more like refreshed? So I want to, you know, kind of go back to PC, which is the bottles and say PC because phosphatidylcholine is a lot to write on a bottle. So yes, which tastes like walnuts. I don't know why. Why is it difficult? And this is a kind of within the zeitgeist of like health conscious people, especially people who have been health conscious for, I would say, over like 15 years. It is like a kind of the same way, like you talk about the weather, you're going to talk about the difficulty of getting good phosphatidylcholine. So why is it difficult to source good phosphatidylcholine? Where would, you know, from your experience, where would companies go wrong sourcing phosphatidylcholine? It's an odd thing that was allowed in the history of soy production. And there's a great book called The History of American Lecithin, my grandfather had on a shelf. And essentially, they used a byproduct of soy production that produced about 20% phosphatidylcholine, and it's combined with essentially vegetable oil. So it's called triple lecithin. It's essentially lecithin is the byproduct. It's then packed with some oil. And that will, when you test it in a lab, it will show that it will yield about 30% phosphatidylcholine. The problem is that's not liposomal. And so most of the phosphatidylcholine on the market is just that product. When you go to a contract manufacturer and you say, hey, I just want some phosphatidylcholine, that's what they're going to provide you. It's essentially lecithin in oil. It's actually called technically triple lecithin packed in oil. And what happens when you consume that is it breaks down into triglycerides and choline. That's not going to provide the building blocks of the cell membrane. Choline's great. Triglyceride's not so much. Yeah. But it's not going to get through the digestive tract into the bloodstream for cellular delivery. Especially not for the brain, right? No, it's not going to cross the blood-brain barrier at all. So what my grandfather did in about 2002 is they were using IV PC in the 1990s when they first started Body Bio. And they were doing it based on blood testing that they were doing and doctors working with extremely challenging neurological issues and chronic illness cases. And he started to develop. It took about four years. One of the gentlemen who he made PC with originally is still at our company. He's one of the longest employees that's been there. And he's currently making butyrate. And they just tinkered around for years, just playing with how do we create a process that's going to yield a liposomal phosphatidylcholine, which is exactly what our product is. So the difference really with us versus other products on the market is we know ours is truly liposomal. We've done extensive testing to prove that. we actually can see how it's taken up into the cells. We did a massive study this year at the University of Connecticut with a mitochondrial research lab just to see how the liposome. So it's not about liposome size. It's not about any of these things. It's about how it's actually absorbed in the body. And that was really exciting to see this year. So for our listeners, if maybe they want to look at the labels of their supplements, if it's not body-binding. You won't know, right? That's the thing that sucks. Just the same with liposomal supplements. Wow. If you look at a liposomal supplement, you're standing in Erewhon or wherever that has a bunch of them, and you look at 10 different companies, I would probably tell you 9 out of 10 are not liposomal. They just put that triple lecithin ingredient in with glutathione, with vitamin C, with whatever, and you can call it liposomal according to the FDA. There's no regulation. There nobody to test it to say this is actually effective It what I say a lot about so it very extremely difficult to explain sourcing to anyone who is not By the way to anyone who even cosmetic chemists like even people who are dermatologists, like if you're one step removed from touching the raw material, you might as well be the end consumer as far as like your level of understanding. And a lot of the times my way to hammer it is saying, do you know how there is a difference between your local butcher, his grass-fed beef, and sorry, McDonald's. I am so sorry, McDonald's, but like meat at McDonald's. Yep, I agree. That obviously is not great. That's less of a discrepancy than between two identical ingredients that you can source for. Agreed. By the way, normally you source raw ingredients you would source them and we would source them almost from the same starting point manufacturers. Obviously, they're going to do. So it's very difficult to know. And I think if someone wanted to choose their partner, their supplement partner in their life, the people who they get supplements from, it's not like you should like the owner of the company, but you should understand how they make decisions. Yeah, it's true. And you should trust their decision-making because you won't be able to understand where they're sourcing their omega-3s and what is their decision-making. I mean, my heart was broken recently where I realized that the omega-3s that I was taking until like two years ago, but for a very long time, decision-making was horrible. And actually, like all of the guests that we bring to this podcast are they all vetted by us like and this podcast episode is not sponsored and none that word here sponsored by young goose who is us yes so but but it's true like whenever um we take it very seriously that people trust our opinion yeah and uh we get questions all the time from our listeners recommend this breadlight therapy device uh supplement stack everything things for everything hair and yada yada yada and we only bring guests that we we know like they're founders of the companies but we know that we can trust them like they would make good decisions like amitai said and i think it's the same for skincare it's the same it's anything you're putting on your body it's in your body and it's hard to make those decisions these days right because so many companies have you know maybe sold and those those decisions then are altered when a company sells. So I'm not going to talk about the company, but we have a company that, I mean, the owners used to be, they're still our friends. And we were very vicariously involved in the trajectory of what happened that a company after it got sold and it got sold to one of the biggest pharma companies in the world, a subsidiary of one of the biggest pharma companies in the world. We have many friends who are still employees of that company. And the only reason the company got bought out is because the parent company had ingredients where they basically was looking for a home for those ingredients. And they literally did like we call it in Hebrew red riding hood. I don't have no idea why, but they switched out the core actives of the same. The formula is called the same. It looks the same, but it's not the same. Well, I think our missions are different than those companies. That's a large conglomerate that's looking at shareholder value. We don't have to do that. And I think it's tough, right? You look at companies that have raised capital and are expanding massively and what they're going to do. And I spend so much time listening to these podcasts about these companies just scaling so quickly when they bring on equity. And you're like, God, that's got to be great. I mean, it's stressful, but cool. I mean, an incredible experience, but they're also looking at the bottom line of every little thing. It has to. Like, that's how you scale massively. You cannot get a certain amount of money, aim to do 10x, but not cut costs. I think most people don't understand that there are two vectors of a company raising in value. One of them is definitely increasing the bottom line, but exactly an opposite and equal force is the force of reducing costs and redundancy. And that's going to look at, they're going to look at every single raw material. So if I pick the best vitamin C out there, they might go in and say, we can get that cheaper and you can cut costs on this. That's the difference. You're saying exactly word for word what we talked about on the bonus episode that we released about companies being bought out. We talked about road getting acquired and some other companies and why we at Yanguz don't have investors. We are not raising money for these exact reasons. Like it's the same exact situation. Like every ingredient that we use, we source. It's like pharmaceutical grade and it's just the purest form and it's expensive. and that results in a certain price points of our products. But yeah, we've already had people that gave us advice, financial advice where like, exactly, like you can have, it's half cheaper and you can bring prices down. More people can experience your products, but it's not going to be the same product. It's not going to do the same. It's not going to be Yanguz anymore. Exactly. And so that's what people often say. Well, your PC is $200 a bottle. It's meticulously made. there's 10 people that go through the process of just manufacturing it it's also a gigantic bottle it's the most ridiculous bottle there's some aspects of the company that have just been kind of grandfathered down literally from my grandfather that like of course i wish i could change the name right there's too much brand equity in the name now but you know if i was starting from scratch i would do a lot of things very differently you know the the starkest example i have for the same ingredient is ergothionin. Ergothionin, there are two companies that are the leaders of supplying it for skincare because it needs to be kind of dialed in for skincare. One of them is in China, one of them is in France. The Chinese version costs $300, the French version costs $5,000. Exactly. So, I mean, you know. Yeah. Actually, in our intro, we would have already introduced you and everything but you mentioned your grandfather quite a bit and I just I think the way I see you you know you're one of like inspirations to me you're like you're this girl boss you know you're you're a mom mompreneur and you're running this company with so much grace and with uh you know and I am curious to hear and for the listeners to hear maybe how the company started and and then And what did you do differently when you took it in your hands? Oh, it was day and night. Yeah. The company was started in… Oh, if you switched them from working at night to working during the day, that would be huge. Everybody works overnight. He started as an entrepreneur. He had heavy metal toxicity. He owned a steel factory. So my family was in the steel industry for a long time. In the 1980s, he had to stop running marathons, was getting really sick. he refused to take that diagnosis. There's nothing you can do about it. And he went to the ends of America. I mean, I think he was in Oregon and Washington State and in California because there was no health and wellness in New Jersey. It was a very small group of people kind of starting the integrative and functional health movement. And a lot of the peers in that space are still around doing different things. But this is at the same time that Thorne was starting and Metagenics and Zymogen and all these companies and way before the days of like an IFM type of thing. So he They started initially doing blood tests. Used to be able to walk into a lab core and get a body bio blood test. Same exact thing as Function Health is today. Used to be able to do that in body bio. And it was $100 a month. Wow. And you could just walk in and get it. But they found that there were certain things that they were seeing consistently. At the same time, they were doing all this research and putting together with doctors, a group of kind of a consortium of doctors, this IV detoxification protocol. And he looked at it and he said, look, everybody needs this. The need is getting greater and greater because of this world that we live in. But it's inaccessible. It's drugs. A doctor needs to prescribe them. And then it needs to be done by IV. So it's a very, very complex grouping of drugs for detoxification. So he went on a journey just to start to figure out how to make them into pill form and into liquid pills, whatever they were, but in a supplement form. And so he developed those. And they were all pretty much developed by about 2006. Took a long time. Yeah. Yeah. And now we have three different manufacturing facilities where we manufacture the different products. And the thing that they were doing really differently is they only sold to doctors. And so they would lecture about 50 doctors a year. They would host this small conference in New Jersey. They would have incredible, I mean, the leading voices in functional medicine, even Mark Hyman has been. And they would lecture these small groups of people. And then those doctors would take it to their practice and they would practice this detoxification protocol. And every single patient that walked into their office, they were putting on PC, they were putting on balance oil. They were putting on butyrate. They were using glutathione. It was the exact same thing as the detox protocol, but an IV form into a nutraceutical. And so when we came along, my husband, he recruited my husband after we got married. My husband really helped build Fiji water in Europe, Middle East, and Africa. And we were living in London. And he said, I need help. I want to do something with this business. I think he always used to say- You can sell water. you can sell plastic bottle. And he said, everybody else has the sizzle, we have the steak, and I just don't know what to do with it. And he thought you needed to turn it into a drug. He was convinced that we had to go down the IND, turn it into a drug route. And my husband got involved. I was heavily pregnant with our first baby. And we kind of sat with him and we said, pop up, you don't have to do it this way. People are really taking their health into their own hands we just have to really lead with education and and lean in on the practitioners that already trust us to be those voices to help amplify and and get the voice out there it took years though yeah it took years but this is really the golden age of i mean we're still in it but the golden age of what we call consumer facing medical yeah technology strategies whatever that is where i mean many things aligned some of them are financial hardships like you know the 2008 crisis some of them are things like covid more recently yeah but there were things that basically detached people from that central nervous system central backbone of of um stringent medicine where you have to go to one person there's many bottlenecks for you to get a solution and people wanted to take, again, micro solutions home to which if they can just adhere to the protocol, they can get results at home. So it's, I mean, it's a beautiful example of this happening. Yeah. Yeah. Let's take a second to talk about skincare during winter. Here's the part most people miss. winter does not just dry your skin. It changes how your skin produces energy and repair itself. When temperatures drop, trans-epidermal water loss spikes, mitochondrial output slows, and the barrier starts losing ground faster than it can recover. This is why skin becomes reactive, inflamed, and unpredictable in winter, even if your routine worked perfectly all year. Most people respond by adding a heavier moisturizer that does not address the problem, so we build a system instead. The Winter Skin Protocol is how we protect the skin when repair capacity is compromised by cold, wind, and low humidity. It is not a generic routine. It is tiered by metabolomic skin age with clear guidance on when the priority should be protection versus repair and how to adjust when travel, treatments or environmental stress push the skin past its threshold. Inside the protocol, you will find structured morning and evening routines, red and near-infrared light timing, and targeted strategies for the areas that break down first in winter, including the neck, chest, and hands. If your skin becomes tight, red, or reactive every winter, this removes the guesswork. If you want to go deeper, you can download the protocol and see the full system. The link is in the episode description. Your skin already knows winter is different. Your routine should reflect that. So we're talking a lot about like kind of cell health forward type metrics, whether it is balance oil, whether it is PC, which both of them are heroes in our house. But you also, again, talk a lot about butyrate. Yeah. And butyrate is different because, well, I'll let you talk about it, but it is a different approach than, hey, body, here's that end molecule you're going to use, you're going to employ in every cellular process. So I'll let you continue. How is butyrate different as far as like a modality than giving the end building block of a process? Yeah, it was part of the original IV detox protocol. So the detox protocol was phosphatidylcholine. It was sodium phenobutyrate. And I'll explain the role in the detox. Glutathione, lucovorin, which has become very popular amongst autism communities, vitamin Bs. That was pretty much the detoxification protocol The role that butyrate has that really fascinating is twofold From a detoxification perspective it goes into the cell and it breaks down the bad stuff that broken through the cell membrane and gone into your cell and embedded itself in your DNA. And it's changing our health trajectories. There's a reason that we have autism. There's a reason that we have neurological disorders. There's a reason children are getting colon cancer in their 20s. These things are not, they were not happening 50 years ago. They were not happening 100 years ago. So butyrate goes in and it shakes off that junk. PC imbalance will go in to remove it from the body. That was the detox theory. From the functional perspective, butyrate's a fascinating molecule because none of us are eating enough fiber or resistant starch in today's world. And butyrate is a postbiotic. It's the end product of a perfectly balanced microbiome. You have the perfectly balanced food that you're feeding the microbiome. You have the right keystone strains of bacteria. And then sometimes they're going to produce butyrate. It's a highly inflammatory molecule, anti-inflammatory. It is... I was like, maybe it's like the charmesis, you know, healthy inflammation. No, that's omega-6. But it's a really, really important molecule, not only for the gut, but for cellular function and detoxification. So it's part of that whole gut-brain axis, gut-cell, skin. I mean, so much is housed in the gut. I mean, And quite frankly, it started the bubble, no pun intended, but started the bubble around postbiotics and the hope that they're going to kind of be the endobiles. Oh, yeah. I started that. I'm claiming that one. Yeah? Oh, yeah. Because when I sat down with my grandfather, I would sit, I would say, pop up, what is butyrate? Yeah. Four hours later, I didn't have an answer. And this is way before the time of ChatGPT, where you could take the whole recording, put it in there and ask it some questions. So we really had to distill, like, what is it? And how do we talk about it? And at the end of the day, they kept calling it a short-chain fatty acid. They said, but short-chain fatty acids are postbiotics. That's what it is. There's several different postbiotics, not many, but it is the keystone postbiotic that is most important for our immune function, our cellular function, our detoxification function, our gut health. Yeah. That's, I think, taking it back to, I mean, Anastasia is the reason we do it, but one of the main modalities that we use for for mitochondrial function is incorporating postbiotics in products that allow better utilization of oxygen or simulate you know mitochondrial function for that matter yeah and um that's why i came up with the term hyperbaric oxygen oh i love that products yeah that's so that basically i put it on before this oh yeah well you look glowy you look glowy so there there is there is a and to be frank like we don't own there's this there is no patent to be owned there there's you can do whatever you want with different back with different like yeast etc to bypass patents that are that do exist and um it's just that i think other companies are just like not noticing that there is like something that like a wonderful modality that can be used for skin health yeah yeah i have a question about vitamin c yeah i know that uh vitamin c for a while it's it's like a you know it's one of the ogs you know in everyone's stack a lot of people think about it just in from immunity perspective but for like an advanced user who is taking vitamin C specifically for skin improvement, sometimes they take vitamin C and they don't see improvement in collagen. What is happening if it's not, like if vitamin C is not absorbed effectively? Same as glutathione, actually. So glutathione and vitamin C are not well absorbed in the body. And so you really want them in a liposomal form. And not to like sit here and plug my products, but I wouldn't take a goo or trust other products. There's actually a great, I do love Live On Labs out of Las Vegas. I love the OG, you know, family-run business. They make liposomal products. But the amount of people who put them in shakes, blend them, and break the liposomes is like, I think, probably 99 people out of 100. Yeah. You're not – yeah. I mean, you have to be careful about how you take these things. But they're not well absorbed in the body. And so you do want them in that form to really get into the cells and to stimulate collagen production. I think when you don't take – look, I think all of these things. When you don't take enough of these building blocks for our skin, you will see effects in your skin if you're not taking it from within. Because we're not getting enough from our food. We should, but we're not anymore. Yeah, yeah. I hear you. But you do raise an interesting point. What would you tell someone who would come to you? And I bet you actually hear that a lot and say, I heard glutathione isn't absorbed orally. It's a waste of time. I don't even understand why you're selling this product or however people phrase themselves when they talk to you. But that is something that we hear quite often. We specifically heard it when I had an immune protocol that I was doing, and your products were part of that immune protocol. So I've heard it personally. So what would you tell someone who says glutathione, just why bother? I mean, most isn't well-absorbed in the body. If you're buying it off Amazon, it's probably not. It needs to be in a liposomal form. It really does, in a truly liposomal form. So look out for things on labels. Companies are getting smarter. So now they're putting, you know, derived from phospholipids, derived from phosphatidylcholine. I would go so far as to call the company and say, hey, do you have any studies proving efficacy of your liposomes? This is stuff you're putting in your body. Take it seriously. Don't just pick it up at the supermarket. And I think when you really do take it seriously, you notice the gains. This is not something you're going to notice right away. You start taking vitamin C in two weeks, you're not going to see perfect, you know, collagen production and your face is going to look plump. But when you invest in the right products, just like you do for topical skincare, and you invest in what you're putting in your body, you will see, I think after about a month, you see definite large gains. Yeah, that's very encouraging, I think. What do you think of the beauty supplement trends? There are so many companies that they're doing skincare, but then they're launching their beauty supplement, and how do you compare that to like cellular nutrition? It's, you know, apples and oranges. It's totally different. I think most, when it comes to manufacturing, you can walk up to a contract manufacturer and you can say, hey, what do you have for skin? And they'll probably have a couple of different blends that they've based off of Nutrafol or something else. And you just kind of select, tick off that box, provide them with a label. This is the type of container I want it to be in. They do all the quality control. They do all the sourcing. You can't swap out ingredients. You can't make changes. You don't know what those raw materials are. You just have that finished product. And so I think these blends are fine. I like that companies like Nutrafol are really doing like clinical studies behind their product to prove efficacy. But I think for the most part, when they pivot into supplements, I always just think like stay true to what your name is. Stay true to what you are stay true to what the brand is really known for just like i wouldn't go making a phosphatidylcholine skin cream although i think it's a great idea i'd love for you guys to do it yeah it's a good idea yeah no a little collaboration yeah yeah we definitely always get encouraged by our community to be like please launch a red light therapy and launch a macronidine pen and launch makeup and launch shampoo and conditioner and we're always like you know i'm not gonna say no ever ever ever but it's no for now because right now we're like like you say we're focusing on what we're really great at and where we have the expertise and we can deliver just the best of the best you know yeah exactly and it's also fun to collaborate with friends and uplift each other you know you do this and you're gonna do some great at that and she's great at that and let's race together instead of becoming competitors agree so let's talk first of all yeah that's why you see why she's the uh she's the one that makes it work um what's her title first of all just put the word co and then put everything yeah but um let's talk about you know you have you have the funny thing to say but like any any um any like online type like um concierge medicine right now are going to tell you 200 years of of uh of collective experience Right. And it's basically but you really do have you house 30 years of product experience, which is rare. Yeah. So from the vantage point of skin health, what have you seen work? How does a protocol look like? And I would even ask you to say, how does a basic protocol look like? Yeah. And then how can people try and push the envelope and see if it works for them? Yeah, I think so. I made it really easy this year because I had so many girlfriends who reached out to me to say my skin looks great. That I was driving one day and my best thoughts come when I'm driving by myself and I don't have the chaos of my kids in the car and I can just think for once. And I thought we should just put together a trio of products. So it's PC, balance oil and liposomal vitamin C. That's your starting place. Start there. Take it for three months. Look at your skin condition. Stop taking it. See if the skin continues like that because it won't. It's the same effects as PC. People often say to me, I don't necessarily feel PC. Well, it's the same people that are probably, they're not tuned in to what's going on in their body necessarily. And then they stop taking PC and a couple of days later, they have brain fog. And then they say, oh, it was the PC. I got to start taking PC again. And it's very similar with the Skin Cell Essentials Trio. So it's three products together, easiest place to start. You're getting those lipids into the body that are feeding the fat content, the healthy fats and the bioactive lipids that our skin needs. and then you're helping with the collagen synthesis that's bringing it all together from vitamin c and typically a lot of us don't have enough vitamin c in our bodies yeah 100 how how would you so i'll give an example when when i have injuries uh due to jiu-jitsu i don't want jackson to hear the producer because i'm pushing him to to jiu-jitsu so jackson i never get injured by the way but i've been trying to tell my husband he's like no hypothetically when i get injured is he also doing jiu-jitsu our son is the oldest one is yeah okay so and of course he never has injuries no not yet but how uh so for example when i do get hypothetically injured i really ramp up my vitamin c if it's a ligament related i really ramp up my vitamin c intake and i do it in a way where i take it multiple times a day so i so there's less because it doesn't last in the body yeah does there's less gut irritation for me specifically my gut doesn't like do you take ours yeah but uh Does it affect your gut? In general, my gut would react to, let's say, more than five grams creatine, for example. My gut really doesn't like instability or irritants or things like that. Interesting. So I really take it like four or five times a day, for example, things like that. So how would someone push the envelope in the example of vitamin C? The biohacker. The biohacker. The biohacker. If one is good, probably 1,000 is better. Yeah. So, yeah. There is no upper limit of toxicity. Look, you take too much PC or balanced oil and you're going to have diarrhea. It's not the end of the world. But we're talking like six tablespoons a day. So I take two tablespoons of PC a day. Two tablespoons? Two tablespoons. You take one at least. I take one. We talked about it in the podcast before. He has to run after me with supplements. I'm not very diligent, but I'm grateful. Put it by your vanity and like first thing in the morning, just kind of take a little chug. Yeah. Glug? Yeah. No, listen, she has me. To follow her with the spoon. And we have to hide the PC, remember? Actually, because of our son, he's asking for more and more. We have to like that. Yeah, that's really cute. That's the problem of like having it out for yourself to remind yourself, but then you know, to remind him. But sorry, we interrupted you. Same with balance oil. You can up it. I think it's great for, you never want to heat it. So balance oil, I'll make a salad dressing. so i'll do a little bit a kind of dash of olive oil just for taste and then the rest of its balance oil and it tastes fantastic it's very mild to our salads as well and i put it mashed potatoes pour it on top kids foods pour it on top kids i make them a chocolate milk every morning with a chocolate protein powder we do balance oil remineralize e-light in the kids for the kids raw milk i love e-light i want to i want to get to it i'm so sorry i was doing uh my skincare routine the other day and we have to wait for our vampire exercise. We have to wait for it to fully absorb. And we ask just, you know, to wait between five to 10 minutes. So it's fully absorbed. I usually wait like three because I can tell when it's absorbed. And I was like, I'm going to put my E-light in the water and I'm going to take it. Like in the meantime, I'm just going to drink some water, you know, something useful. Yeah. And just drink your minerals. That's a great idea. I'm going to do that. I need that product. Oh, yeah. This is the best product we've ever made. Anyway, Oh, I'm excited. Oh, yeah, it's incredible. But so I do want to go one by one because I think it's... Oh, and then wait, because we forgot. Exactly. Like the upping the dose. Yes. Every four hours, you could do two to four capsules of vitamin C, up to 4,000 milligrams. And then the last one I would say that's really interesting... I might push it to 10, by the way, but don't be me. I don't know, if you want to. For after injury, for Juditsu, you should try Resolvin, which is our fish oil. But it's phospholipid. It's caviar. It's herring roe, cold pressed. deal in so it has the spms in it which are incredible unbelievable studies that have been done on psoriasis and eczema using this now i would not take it every single day i'm not a fan of fish oil every day that's why you take your balance oil every day a couple times a week add in fish oil eat as much fresh fish as you can if you are having a skin autoimmune condition or if you are having joint pain or if you're having muscle pain from you know going too hard at jujitsu then you can up your resolvin dose. And you're saying you're not a fan of fish oil every day because of the anti-inflammatory effects of it? Yes. After long-term effects, it will start to act as a steroid. But the other thing is it offsets the omega-6 and omega-3 ratio in the cells. And you still need those omega-6s. So let's say you are really into health and wellness and you're super anti-seed oil. You're not even, I mean, the really crazy ones aren't even eating egg yolks because they're too high in linoleic acid. We need linoleic acid. We need egg yolks. We need egg yolks. You need these. These are superfoods for our mitochondria You need linoleic for the cardiolipin production within mitochondria So I just like to have a good balance of those sixes and threes which is why I never say fish oil every day Interesting I have a question and then we got to get into the rapid fire But we're not done with the protocols at all. I have so much to go. No? Okay. So go with the protocols. No, I'll do it in the rapid fire. Okay. So one question I had, and we kind of always tend to ask this when we bring someone, like an expert in their area, are there any mistakes that someone can make when they're decided to take up like this challenge of supplementing for skincare from within? And what are the common mistakes that you see people make? If you're doing the higher dose, if your gallbladder and your bile function are not optimal, you can definitely get that nausea. Have you ever had that kind of nausea when you eat too much fat or eat eggs? That's gallbladder stagnation. And so you need to make sure your bile flow is working, which is why if you have a history of gallstones, if you have a history of gallbladder issues or your mother or father had their gallbladder removed, make sure you're doing some Tudka or taking something like ox bile or TADCA with your healthy fats like PC and balanced oil so that you are getting the right amount of fat and that fat is actually getting absorbed through the liver and the gallbladder. Would you do TADCA together with, if you're taking PC and balanced oil anyway, would you? I do. I do. It has such great neurological benefits as well. Okay. So I want to run through, we'll do it like a rapid fire, but I'm going to run through So a few like maybe points of interest. Great. And, you know, just people can read the back of labels. People could ask, you know, Chagipiti the protocols if they really want to, but back of labels are great. Someone is interested in anti-aging. We said the three, the top three are liposome vitamin C, PC, and balance oil, right? Yes. Okay. For skin or for brain? For skin. Those three in the bundle. easy what about if someone has you know pigmentation has issues with you know things like again glow pigmentation things that are more pigment and and oxidative stress related more vitamin c more vitamin c what about the glutathione is it is it also do glutathione definitely what about if someone has acne you need the tadka for liver you got to add in tadka you probably want to up your pc yeah maybe vitamin c for just because it's i think it's important but I think a lot of hormonal acne in particular is that liver is backed up. It's not processing the hormones correctly. Maybe you have a history of being on hormonal birth control, something like that, that is causing those issues. Get that liver moving, flowing. Tudka is like your liver enzymes just immediately go down. It's incredible. Okay. Pregnant or postpartum and within the confines of skin support? PC, balance oil, vitamin C, all safe. postpartum, not during pregnancy. I think those are three super important supplements for pregnancy, mainly PC and balance oil. Postpartum, you're going to add in. When you're breastfeeding, do it once a week, some Tadka. When you're done breastfeeding, you can do Tadka for a month, get those livers, get the hormones detoxified from the liver properly. Great combo. And then the last one is pre and post procedure. Let's say someone is, again, like even though I put it, it's still true that you should do, you know, once every month your microneedling or whatever that is. You know, if you had surgery, if you did this, that, or the other, you know, you've introduced some injury and some assault to the skin. How would you support it? Kind of how do you prepare for it? And how would you support it afterwards? So pre, they're going to tell you to stop taking any type of fish oil. And that includes something like balance oil, which is an omega six and three. That's for blood thinning purposes. You can continue to take PC. You can take vitamin C beforehand. And I would also take glutathione. Afterwards, you're going to want to take high-dose PC, get back the, particularly if you were under anesthetics, you're going to want the benefits for your mitochondria. High-dose PC, balance oil, glutathione, two in the morning, two at night. Vitamin C, and add in resolvin, that fish oil that we make, because that is super anti-inflammatory and has the naturally occurring specialized pro-resolving mediators. And those are what go into the source of the inflammation and just put the fire out. They're incredible. And resolving for your, and that's the last one, and then we're going to go to legit fire, not like pirate rapid fire questions. And resolving as a longevity strategy, would you say once a week? Like how often would you say that? Yeah, one to two times a week. It depends on how often you're eating fish. You guys probably fish a decent amount here. I did a wonderful pate. I know. I was going to say, he just did a 13th pate the other day. And it was honestly amazing. Love that. Yes. yeah thank you instagram anchovies yeah yeah caviar when you can oysters yeah they're all superfoods yeah nice okay you can go okay i can go with actual rapid fire questions okay so these ones you answer like in a rapid matter and those make great for like instagram clips okay okay coffee first thing in the morning yes or no and why no blood sugar regulation benefits okay the one wellness trend you think is completely misunderstood right now? Sea moss. The most ridiculous thing I've ever heard. Yeah. Just get your minerals from some minerals. Why are you eating the sea moss that is mostly grown in pools and it's completely contaminated? I'm not a fan. Okay. I love that you brought it up. We didn't talk about it in the podcast, so that's great. The supplement you want travel without? PC. Okay. Yeah. I just mentioned that I traveled recently without it. So like I'll learn from you. Okay. Your current favorite daily skin ritual that has nothing to do with skincare. So no topicals. Oh, I'm a skincare junkie. So my like wind down routine at night, this is not a rapid fire, but I could really go into this. I do like red light. So I am using the Therabody face mask. I'm trying to use it every day, but that's hard. I put my face in cold water in the morning, first thing in the morning. That's not skincare. hair. What else? You know, the other thing I think that we overlook that's really important is circadian biology and getting your eyes exposed to sunlight, no sunglasses, first thing in the morning. I think that's really important. And I also think sun for skin. I think it's important for skin health. To support what you're saying, one of the surprising ingredients that we see contribute to hair growth. And a lot of the times, by the way, these two are linked hair growth and skin health is melatonin, topical melatonin. Exactly. Because it cues, it basically kind of sinks your circadian rhythm. So people putting it at night, cueing their hair follicle to basically go into repair or regeneration mode. Yeah. Yeah. Okay, we got three more. One sign your cells are inflamed, even if your skin looks fine. Any type of chronic illness. Any type of, I mean, I hate to say this, but brain fog, fatigue, headaches, all of that. Yeah. Okay. the biggest misconception people have about omega-3s oh they were we're fish everybody thinks we're fish take omega-3s it's super important dha is very important for our brain yeah but the proper ratio in our cell membrane is four to one four part six one part three and if you're not out there eating fried foods and a ton of canola oil i would argue you are most likely completely deficient in omega-6 yeah wow this major but the average american i think they have a one to six ratio, right? How did they do that testing? And who are they testing? And also, are they doing plasma testing? Are they looking at the red blood cell fatty acid analysis? Plasma testing, most tests out there right now are looking at blood plasma levels of what you have eaten in the last week. So if you didn't eat any fish in the last week, your ratio is going to be completely skewed. So when you look at a red blood cell fatty acid analysis, it actually looks at the cell membrane, oh, it's looking at years. And it's looking at the overall structure and fluidity of the actual cell membrane. And that is where you really see omega-6 deficiency show up. Okay, one last question. Beauty from within, is this the future of skincare and will it replace the skincare? No way. No way. I think it's a combination. You need both. I think we really need to start looking at both. You have to think really carefully about how we're nourishing our bodies, but also what we're putting on to take care of those things, particularly as we age. I mean, it's a huge thing for me. I, you know, you're looking in the mirror and you see everything. I'm 42 and I'm like, what am I, you know, what's next? I'm doing all the lasers and doing all of these things. I think topical skincare is part of it. I don't think you can abandon it at all. Yeah. Thank you. Yeah. I love that. That was great. Yeah. Well, let's end up by saying, you know, we talked a lot about your products obviously we're junkies so it's easy how does someone you know start their journey where is it best from your experience where do you get your products yeah in the the shortest you know kind of supply chain way because that is also something to consider right like how how fast from point of production to the words you know For example, in the balance oil example where it's in my fridge, what's the best way to order products? From our website directly. It's always best, bodybio.com. We ship internationally through bodybio.co.uk. We do sell on Amazon. So if you're a crazy person who needs your product the next day, you can get it on there. Just make sure the seller is bodybio because there are fake products and unauthorized resellers showing up all over the place. And if you have any international listeners, iHerb. iHerb is a really great way to get things into other countries. that we don't have the proper labels for or something like that. So that's also very easy. As the famous saying goes, the best compliment are fake stores on Amazon and fake Chinese companies trademarking your brand in China. We have that happening. Do you guys have that happening? Oh, yeah, for sure. The two best, by the way, compliments that I can receive. But on that note of international listeners, we recently looked at our statistics and we have 55 other countries besides the US listening to us so thank you guys it's so fun thank you, spasiba, namaste gracias grazi, shukran teşekkür yeah I learned it today because I got my hair done with the Turkish what did I want to say so on that note we also want to announce a little milestone that our podcast hit we are officially number one in beauty and fashion thank you guys so much and then what did we do we went away from it yes i mean that is the right too we also just switched the category to alternative health where we are ranking uh seven so which is also really fun to be in top 10 but we do need your continuous uh reviews those helps so much and um we've been getting so many of them and we have a little tradition where we read the review just love the best tradition of all times yeah well we read the review and thank you for your review and send your product oh i love that so yeah they get a free uh blue peptide spray oh yeah nice i'm gonna do you want me to do it sure okay i'm just gonna Choose a random one? Is that how it goes? Well, it's whatever you want. Sometimes I do the most recent ones. Sometimes I actually, when I have time, I do read them all. But sometimes in the moment, like now, I go for just the one that caught my eye. So I'll tell you a secret, okay? If you just go to the thing, it's not going to give you the recent ones. It's just going to give you like a popular one or something. I don't know about top viewed, but like... How is it popular? I'm going to choose it by name. I'm going to go with... Wow, that's a cool one. Aria in the Sky with Diamonds. Oh. Yeah. The conversational tone of this podcast makes the science of skincare easier to understand, even if you're newer to the idea of skin longevity. I've recommended it to several skincare newbie friends, and they love the more approachable tone. I love that the hosts don't always agree on every single thing. It creates a thought-provoking dialogue. Maybe that's what our sons, like, looking at us, arguing. I love that the hosts... I appreciate the minimal small talk and the straight talk about which skincare trends may be nothing more than trends. This is the only skincare podcast I impatiently await every week. Oh, that's wonderful. That's very nice of you. Aria in the sky with diamonds. Yes, you can either email service at theandcask.com and we'll send you your product or you can DM us on Instagram. And thank you, Jess, for saying what's up for her. Thank you so much for coming. Thank you. It was such lovely to chat with you and I love your product. I love your product. So what about the review on the Apocos? I'll leave you a review. I use the whole hyperpigmentation kit. But now I need some new products. I need the Vampire. Oh, you're going to, I'm telling you, the Vampire Exosomes, you know, here's the thing. I love recommending the Blue Peptide Spray because it's affordable. Everyone can afford it. However, you know, and I love that product. It's an amazing product. However, Vampire Exosomes is by far what gave me the best results. It's like so nice to recommend it. Anyway, Jess, we've been, just to summarize it, we've been using your products for the longest time. Thank you. way before we knew you. We believe in what you are doing and we are so, so grateful to know you personally and have you on here. Thank you. Same to you guys. Thank you. Bye. Bye, everyone. Thank you.