Dr. Jockers Functional Nutrition

The Hidden Dangers of Cholesterol Medications (Doctors Don't Tell You This!)

19 min
Feb 5, 20262 months ago
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Summary

Dr. Jockers examines the hidden dangers of statin drugs, explaining how these commonly prescribed cholesterol medications damage mitochondrial function and increase risks of type 2 diabetes, dementia, and muscle weakness. He provides alternative dietary and lifestyle strategies focused on metabolic health, blood sugar stabilization, and inflammation reduction rather than LDL cholesterol lowering.

Insights
  • Statin drugs inhibit CoQ10 synthesis and damage mitochondrial respiratory function, reducing cellular energy production and increasing oxidative stress throughout the body
  • LDL cholesterol reduction has minimal impact on heart disease risk; triglyceride-to-HDL ratio and metabolic flexibility are more predictive of cardiovascular health
  • Populations over 65 and women with smaller body frames face significantly higher statin side effect risk due to pre-existing mitochondrial fragility
  • Cholesterol functions as a healing and repair compound (like firefighters), not the primary cause of disease; inflammation is the actual target for intervention
  • Intermittent fasting, protein-rich whole food diets, and resistance training can achieve metabolic health outcomes without pharmaceutical intervention
Trends
Growing skepticism of pharmaceutical cholesterol management paradigm in functional medicine communitiesIncreased focus on mitochondrial health as foundational to chronic disease prevention and reversalShift toward triglyceride-to-HDL ratio and fasting insulin as primary cardiovascular risk markers over LDLRising interest in metabolic flexibility and fat-burning capacity as health optimization metricsExpansion of personalized genetic testing (APOE4 genotyping) for dietary protocol customizationIntegration of intermittent fasting and circadian-aligned eating windows into mainstream health protocolsEmphasis on sun exposure and vitamin D optimization as cholesterol metabolism regulatorsGrowing awareness of seed oil toxicity and inflammatory cascade in modern food systems
Topics
Statin-induced mitochondrial dysfunction and myopathyCholesterol metabolism and cardiovascular disease riskType 2 diabetes and metabolic disease causationMitochondrial biogenesis and cellular energy productionBlood sugar stabilization and insulin sensitivityIntermittent fasting protocols and metabolic flexibilityTriglyceride-to-HDL ratio as health markerAPOE4 genotype and dietary fat recommendationsVitamin D deficiency and statin side effect riskInflammation markers and C-reactive proteinResistance training for metabolic healthSeed oil toxicity and inflammatory responseCoQ10 depletion and muscle weaknessMitochondrial apoptosis and muscle cell damageSleep optimization and regenerative health
People
Dr. Jockers
Host and functional medicine practitioner discussing statin dangers and metabolic health alternatives
Quotes
"Cholesterol is kind of like firefighters showing up. It's a healing and repair compound in the body. So it's kind of like if a house is on fire, the firefighters show up. Now it's not the firefighters that started the fire. They're just there to help put out the fire."
Dr. JockersMid-episode
"Statins have been shown to decrease mitochondrial respiratory function, and increase oxidative stress and damage to the mitochondria. This results in lowered cellular energy production."
Dr. JockersEarly-episode
"The only thing statins have really been shown to do is lower cholesterol, but not actually significantly reduce your risk of heart disease or dying of a heart attack."
Dr. JockersLate-episode
"Your triglyceride to HDL ratio should always be less than two. Two parts triglyceride to one part HDL. And really as close to one as possible."
Dr. JockersMid-episode
"There is no withdrawal from coming off of statin medications. When it comes to statins, you don't actually have to do that. There's no side effects of just coming off the statin medications."
Dr. JockersLate-episode
Full Transcript
So what are the most common side effects of using statin drugs? Well, there's something called muscle weakness or SAMs, which is statin-induced muscular dystrophy. And so basically the muscle system is not able to function well because the mitochondria are so damaged. Also, things like depression, erectile dysfunction, memory loss, digestive problems, high blood sugar, type 2 diabetes, headaches, low platelets, trouble-sleeping, and skin problems. Well, welcome back to the podcast, important episode here, on the hidden dangers of cholesterol medications, and doctors will not tell you this. This is critical, if you know anybody that is concerned about having maybe high cholesterol or perhaps they or a family member, a parent or something like that, is taking cholesterol medications. This is an episode they definitely want to hear about because there are some hidden dangers with these medications, and there are some quick fixes for those dangers. And that's what I go through in this video. So it's really super important that you, anybody that's taking a statin drug, a cholesterol-lowering medication, they really need to understand this information. So again, please share this with them. And of course, if you want personalized one-on-one health coaching, we have got it for you at dockerjockers.com. We've got the best health coaches in the world, and they work one-on-one with people. They personalize health coaching programs based on your labs, based on your unique health history, and really help you accomplish your health goals. So check us out, check out the long distance coaching banner on dockerjockers.com, or email us at info at dockerjockers.com, and just request health coaching on your email, and we will connect you with our health coaches, and walk you through the steps to get the health coaching you need to accomplish your health goals. So without, with that said, make sure you take a moment, leave us a five star review on this podcast, and let's go into the episode on the hidden dangers of cholesterol medications. Thanks for being a part of our podcast community. God bless you guys, and let's go into the episode. Hey, in today's video, I'm talking about the hidden dangers of cholesterol medications. Cholesterol medications, in particular, statin drugs, are some of the most commonly prescribed medications in the world, but they could be increasing your risk of type two diabetes, dementia, and Alzheimer's. You see statin drugs. Again, they're some of the most commonly prescribed medications. They're used to lower your bad cholesterol, your LDL levels, and supposedly reduce your risk of cardiovascular disease, heart attacks, and stroke. The unfortunate reality is that they don't meaningfully reduce your risk of heart disease, and studies actually show they increase your overall risk, a developing muscle loss called sarcopenia, lowered libido, and erectile dysfunction, as well as metabolic diseases, such as type two diabetes, and fatty liver disease, as well as neurodegenerative conditions, such as dementia, and Alzheimer's. What's the reason for this? Well, statins have been shown to decrease mitochondrial respiratory function, and increase oxidative stress and damage to the mitochondria. This results in lowered cellular energy production. Ultimately, when we have damaged mitochondria, we're not going to be able to burn fat effectively for fuel. We're going to create more inflammation in our body, and it's going to accelerate the aging process, leading to all forms of chronic disease. So what are statin drugs? Well, statins are a type of medication that's commonly used to lower low density lipoprotein or LDL. We call that many people in society call that bad cholesterol. And supposedly, that reduces your risk of cardiovascular disease and stroke and prevent cardiovascular disease from getting worse if you lower these LDL cholesterol. There are seven types of statin drugs available in the market today that are currently approved by the FDA. They include fluevo statin or lipitor. They include provocal, zochore. They include crestor, which is one of the most common ones that are out there. You see, these statins are the most commonly prescribed pharmaceutical drugs in the world, but there's some important things we need to understand about cholesterol. Number one is it's essential for cellular function, and your brain is roughly 30% cholesterol. Cholesterol is also necessary for the production of key hormones to testosterone, progesterone, and estrogen. Low cholesterol leads to fatigue, hormone problems, weakness, memory loss, and dementia. So we have to ask this question, how do statin drugs work? Well, they block the activity of the liver enzyme, HMG-CoA reductase. That's in charge of cholesterol production. They also, while they're blocking HMG-CoA reductase, they also block the synthesis of co-inzyme Q10, which acts as a mobile electron carrier, facilitating the transfer of electrons from complex one to complex three in the electron transport chain for cellular energy production. We know statins can directly inhibit the activity of the respiratory chain complexes, one, three, and four, which are involved in energy production through oxidative phosphorylation. Basically, they stop our mitochondria from producing cellular energy. They drive up oxidative stress and damage mitochondrial function. We know statins can lead to an increase in what we call reactive oxygen species, ROS, in the mitochondria. And again, that damages mitochondrial components and impairs their function. They also dysregulate calcium metabolism in the mitochondria, which can affect mitochondrial function. And that can contribute to higher levels of oxidative stress and muscle damage. Some studies have shown that statins can induce mitochondrial apoptosis, potentially contributing to muscle cell damage. In fact, it's one of the main side effects is this myopathy where people have major pain in their muscles. And that's because of this concept where they'll actually increase apoptosis in the mitochondria of the muscle cells causing muscle cell damage. They also impair mitochondrial biogenesis. We know that statins are associated with a decrease in the ability to form new healthy mitochondria. So we end up with just damaged, senescent old mitochondria. And that interferes with your ability to burn fat for fuel. And that potentially impacts energy production. Obviously, you're not going to be able to produce as much energy in the cell. And the cell's forced to survive on glucose metabolism, which drives up more oxidative stress and inflammation in the body. So what are the most common side effects of using statin drugs? Well, there's something called muscle weakness or SAMs, which is statin-induced muscular dystrophy. And so basically, the muscle system is not able to function well because the mitochondria are so damaged. Also, things like depression, erectile dysfunction, memory loss, digestive problems, high blood sugar, type 2 diabetes, headaches, low platelets, trouble sleeping, and skin problems. Now, here are some of the main risk factors for getting those side effects. Females have more of these side effects than males. Particularly females that are over 65 years of age. Basically, anybody over 65 years of age is going to have a higher risk of having side effects from statins than people that are younger. And that's really problematic because people over 65 are almost always put on statin medications. And again, they're the population group that's going to be most susceptible because they have more of these damaged senescent mitochondria. So their mitochondria are more fragile to begin with. So when they start taking the statin medications, it costs further damage to the mitochondria, and therefore they have more of these major symptoms. People with smaller body frames, particularly women with smaller body frames, tend to have more of these statin side effects. If you're taking multiple medications, you're going to be at greater risk. If you're drinking a lot of alcohol, you have kidney or liver disease, or really important, if you're vitamin D deficient, you're much more likely to have major side effects from statin medications, because vitamin D is so critical for hormone function, so critical for mitochondrial energy production, keeping inflammation under control. So if you're deficient in vitamin D, your risk of having side effects from statin medications just goes up pretty substantially. So what can we do instead of relying on statins? That's the question we got to be asking. Well, first off, we have to question, do we really need to lower your LDL cholesterol? Studies show that lowering LDL cholesterol has a very minimal effect on reducing your risk of heart disease and stroke. There may be some benefit to doing it for people who have already had heart disease and strokes, but you know what's more important? Lowering inflammation in your body. That's really the key. You see, cholesterol is kind of like firefighters showing up. It's a healing and repair compound in the body. So it's kind of like if a house is on fire, the firefighters show up. Now it's not the firefighters that started the fire. They're just there to help put out the fire. Well, that's kind of what cholesterol does. It's helping with creating scar tissue. It's helping with healing cell membranes. It's bringing all kinds of important cargo to the cell. What we need to do is not necessarily demonize the cholesterol and lower cholesterol. We don't need to get rid of firemen if we want to have less fires. What we need to do is stop the fires, stop the inflammation in the body. So what can we do to do that? Number one, blood sugar stabilizing diet. This is the most important thing. We want to make sure we're prioritizing good protein, healthy fats, right? Making sure we're getting good quality protein, 30 to 50 grams of protein per meal is what I recommend getting it from things like grass fed beef, bison, lamb, poultry, pasture raised eggs as well as wild caught fish, right? So getting good quality protein, good healthy fats from things like high polyphenol, extra virgin olive oil, avocados, things like that. And then lots of colorful fruits and vegetables. Really trying to focus on a whole food-based diet. That's high in protein, high in healthy fats. That's gonna help stabilize your blood sugar, bring down insulin, help your mitochondria, use fat for fuel more effectively. You can also throw in a lot of herbs, things like basil, oregano, thyme, sage, rosemary, all of those things help support mitochondrial function and help you burn fat for fuel. Apple cider vinegar, the compound in there, acetic acid has been shown to help regenerate healthy, or read, basically stimulate something called mitophagy, breakdown of old damaged mitochondria and create new healthy, stress-resilient mitochondria. So if you've been on statins taking something like apple cider vinegar to help your body heal those mitochondria, really, really good, really important. So taking a tablespoon of apple cider vinegar, once or twice a day in water, diluted in water, four to eight ounces of water, can be really, really helpful for stabilizing your blood sugar, turning back on healthy mitochondria. 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Those are gonna get really good quality mono-en saturated fats. What you do wanna avoid is your seed oils, corn oil, soybean, safflower, cotton seed oil, peanut oil, all those things are really toxic and inflammatory for the body. They are gonna cause high triglycerides, insulin resistance. They're gonna cause all kinds of problems. In fact, when you're looking at your cholesterol, the only thing you really need to look at, LDL is not really that important. What you wanna look at is your triglyceride to HDL ratio. How many triglycerides you have should be under 100, and how many parts of HDL? High density lipoprotein. They call that the good cholesterol you have. Should be up over 50. And your triglyceride to HDL ratio should always be less than two. Two parts triglyceride to one part HDL. And really as close to one as possible. So if you have like 70 triglycerides and 70 HDL, that's ideal, right? That's really good triglyceride to HDL ratio. It's really the most important thing that we're looking at when we're looking at our overall cholesterol levels. That tells me that you don't have a lot of circulating fatty acids, which is important. That means that you're more insulin sensitive and you're able to get nutrients into the cell for energy and you're able to burn fat effectively for fuel. That's what it tells me. It tells me you're more metabolically flexible and metabolically healthy. So we talked about blood sugar stabilizing diet. What else can we do? A huge advocate of intermittent fasting, simple, easy thing to do. Eat your meals in a, let's say, a eight hour eating window, maybe a six to eight hour eating window every day from 10 AM to 6 PM or 12 PM to 6 PM or 12 to 8. Eat two to three really good meals. Don't snack. Blood sugar stabilizing meals, high in protein, healthy fats. And then outside of the meal times, you're fasting. You're hydrating your body well, drink a lot of water. You drink bicarb, herbal tea, but avoiding calories during your fasting window, which should be roughly 16 to 18 hours, a day on most days. If one day a week, you eat in a 12 hour window, not a big deal. Make the other days a 16 to 18 hour fast and eat your meals in a six to eight hour eating window and get the benefits of intermittent fasting. So better fat burning, better blood sugar stability, better insulin sensitivity, better mitochondrial health, autophagy where you're breaking down old damaged cellular proteins and regenerating them into new healthy cellular proteins. You get all those great benefits. So make sure you're doing that regular exercise. You know, I recommend moving your body regularly, trying to get at least 10,000 steps every day, also adding in resistance training, getting 15 to 20 minutes, three to four days a week of strength training for your whole body, upper body as well as your lower body. So you could do two days a week of upper body, two days a week of lower body. However you want to do it, you only need about 15 to 20 minutes, three to four days a week, roughly about 60 minutes altogether, split up throughout the week of strength training. So you could build really good healthy muscle tissue and that will help keep you metabolically healthy. You also want to prioritize good sleep, make sure you're doing everything you can to optimize your sleep hygiene and get really good regenerative sleep. Also get in the sun. Believe it or not, getting in the sun actually converts cholesterol into vitamin D. People are not getting enough sun, may end up with high LDL cholesterol because they're not converting 70 hydrochlessdraw into vitamin D. And so getting in the sun helps activate that, that cholesterol compound and turns it into 25 hydroxy vitamin D. Last but not least, if you are concerned about high LDL, watch your coffee. Now I'm not saying coffee is bad for you, okay? Fat coffee has actually been shown to help stabilize your blood sugar, improve insulin sensitivity and improve your overall metabolic health. However we know that unfiltered coffee like French press or espresso, it contains these compounds called dieterpenes that increase cholesterol level. So you may end up, you're drinking a lot of that, you may end up with high LDL cholesterol but it doesn't again, it doesn't mean that you have poor metabolic health or that you're at an increased risk of heart disease, cardiovascular disease. So ultimately, the key again is make sure you're metabolically healthy. Keep your body very insulin sensitive. Follow a blood sugar stabilizing diet and lifestyle. Keep your toxic load down. Make sure you're moving and building muscle on a regular basis. And again, the labs to look at, the more important ones, when we're looking at cholesterol is your triglyceride to HCL ratio, trying to make sure that's always under two and ideally as close to one as possible. If you throw in a fasting insulin test, that's another great one, making sure your insulin levels are under six. And look at your inflammatory markers, like C-reactive protein for example, make sure that that's under two and ideally under one to keep your inflammation levels down and under control. If you do that, you're gonna be totally fine. You certainly don't need statin medications. And here's more good news. There is no withdrawal from coming off of statin medications. So whereas, you know, different medications like blood pressure medications, and many cases blood sugar medications, antidepressants, you need to wean off of them with the guidance of a practitioner. When it comes to statins, you don't actually have to do that. There's no side effects of just coming off the statin medications. The only thing statins have really been shown to do is lower cholesterol, but not actually significantly reduce your risk of heart disease or dying of a heart attack. So it's not something you need to be afraid of. Of course, all my videos are just for educational purposes. They're not meant to replace the advice of your physician, but I will say from my experience, most people have no major issue coming off statin medications and just following a metabolically healthy diet and lifestyle. So hopefully you guys got a lot of value out of today's video. Of course, check out the article, the in-depth article on statin medications on Dr. Jockers.com. We've got tons of great content there for you and the best infographics in the world right there. DrJockers.com search whatever it is that you're looking for. Of course, share this video with anybody that you know and that you care about. And we'll see you on a future video training. Be blessed. Well, that's all for this show. And I want to thank you again for spending your valuable time with me today. And if there was something you heard in this interview that you have questions on or you want to dive into deeper, then DrJockers.com is the best place to go. If you enjoyed this episode, please consider taking just a quick moment and giving us a great review. Your reviews help us influence more people and transform more lives. And if you took something valuable away from this episode, then please share it with someone in your life you know it can help. We'll see you soon on a future podcast. Be blessed, everybody.