Podcasts · Technology

Latent Space: The AI Engineer Podcast

289 episodes · 20 with AI analysis

The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al. Full show notes always on https://latent.space www.latent.space

AI Intelligence · across all analyzed episodes

People · top 20

Companies · top 20

Topics · top 10

Enterprise AI Adoption Patterns×2Enterprise AI deployment×2High-Throughput Experimentation×2Ambient AI and seamless background intelligence in clinical workflowsClinical decision support systems and real-time prior authorizationAI evaluation rigor and zero-error tolerance in healthcareDocumentation burden reduction and 'pajama time' eliminationEHR integration and interoperability requirementsMulti-stakeholder product design (clinicians, patients, payers, pharma)Proprietary data flywheels from clinical conversations

Analyzed Episodes

May 14, 2026

AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge

Ambient AI and seamless background intelligence in clinical workflowsClinical decision support systems and real-time prior authorizationAI evaluation rigor and zero-error tolerance in healthcare

Latent Space: The AI Engineer Podcast

Analyzed Episodes

AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge

🔬Doing Vibe Physics — Alex Lupsasca, OpenAI

AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)

Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO

Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion

Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony

Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"

Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun

Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample

🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik

Dreamer: the Personal Agent OS — David Singleton

Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop

Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer

NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)

Cursor's Third Era: Cloud Agents

Every Agent Needs a Box — Aaron Levie, Box

METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity

[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka

🔬Nature as a Computer: Prof. Max Welling, CuspAI on AI x Materials Science

Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis