The Secret Peptides and Underground Compounds Doctors Won’t Talk About : 1413
59 min
•Feb 10, 20262 months agoSummary
Dave Asprey and Dylan Gemelli discuss research chemicals, SARMs, peptides, and underground biohacking compounds for longevity and performance optimization. They explore the efficacy, risks, and regulatory landscape of these substances, challenging conventional medical narratives and advocating for personal medical autonomy in health optimization.
Insights
- Research chemicals and SARMs (like LGD, S4, MK677) can produce significant physiological changes (29 lbs muscle in 6 weeks) but require understanding of proper dosing and side effect management to avoid harm
- Regulatory gray areas around 'research chemicals' and 'not for human consumption' labeling create opportunities for biohackers but also risks; FDA attitudes toward peptides and testosterone are shifting toward more rational, evidence-based approaches
- Strength and neural drive matter more for longevity than muscle mass alone; VO2max studies use broken algorithms, suggesting current longevity exercise dogma may be misguided
- Testosterone optimization via oral forms like Kysetrex offers advantages over injection (no ball shrinkage, circadian dosing) and lowers all-cause mortality when levels are adequate
- Medical autonomy and personal experimentation are framed as fundamental rights; the biohacking movement prioritizes self-directed health optimization over institutional gatekeeping
Trends
Shift from injectable to oral testosterone replacement therapy with improved side effect profilesGrowing FDA receptiveness to peptide fast-tracking and rational scheduling of compounds like testosteroneDecentralization of health optimization: functional medicine practitioners and direct-to-consumer testing replacing traditional insurance-based healthcareIntegration of neuroscience and mind-body connection into performance optimization (Apollo Neuro, neurofeedback, breath work)Peptide market explosion from ~7 options (2011) to thousands, driven by bodybuilding and longevity communitiesReframing of 'performance-enhancing drugs' as legitimate health tools when used properly, challenging stigmaLow-dose nicotine adoption for neuroprotection and cognitive benefits despite smoking stigmaCarnivore and high-fat diet adoption as alternative to calorie-restriction and plant-based approachesMelanotan and PT-141 peptides for libido and circadian optimization gaining mainstream biohacker adoptionMedical autonomy activism: resistance to pharmaceutical mandates and advocacy for self-directed treatment protocols
Topics
SARMs (Selective Androgen Receptor Modulators) - LGD-4033, S4, MK677, S23Peptides for longevity - ipamorelin, CJC-1295, sermorelin, melanotan, PT-141, motziapide, semorelinTestosterone replacement therapy - physiological dosing, oral vs. injectable, KysetrexGrowth hormone optimization - MK677, peptide alternatives, glucagon testingNicotine as neuroprotective compound - Alzheimer's prevention, mitochondrial uncouplingCardiovascular health optimization - LP(a) reduction, plaque reversal, ejection fraction improvementDietary approaches - carnivore diet, high-fat nutrition, calorie optimization for performanceExercise physiology - zone two training, HIIT vs. steady-state cardio, strength vs. muscle massRegulatory landscape - FDA approval processes, research chemical legality, medical autonomyNeuroscience integration - Apollo Neuro, neurofeedback, mind-body connection for performanceBiomarker testing - at-home labs, hormone panels, cardiovascular imagingCircadian optimization - sunlight exposure, melanotan timing, oral testosterone dosingSupplement stacking - multi-compound protocols for synergistic health outcomesMedical autonomy - personal experimentation, self-directed treatment, resistance to institutional gatekeepingBiohacking community - Beyond Biohacking conference, tribal knowledge sharing, cross-discipline integration
Companies
Unlimited.life
Dave Asprey's medical partnership offering personalized health protocols and peptide/SARM guidance
Air Doctor
Air filtration company using ultra-HEPA filters; Dave uses in multiple rooms for mitochondrial health
Our Place
Toxin-free cookware manufacturer offering PFAS-free pans; Dave uses for 6+ years
Stem Regen
Stem cell mobilization supplement company; Dylan attended Stem Regen conference, Dave uses product
Axo.health
At-home lab testing company owned by Dave Asprey for hormone and biomarker analysis
Insider Expeditions
Expedition company offering Antarctic voyage with longevity experts; Dave promoting March trip
Palo Alto Medical Foundation
Traditional medical institution Dave fired for dismissing vitamin C supplementation
Mayo Clinic
Dylan visited for cardiovascular health; recommended statin therapy over PCSK9 inhibitors and Vascepa
Apollo Neuro
Wearable neurotechnology company; Dave is advisory board member, Dylan wearing device during interview
People
Dylan Gemelli
Guest; former bodybuilder transitioning to biohacking, discusses SARMs, peptides, and personal health optimization
Dave Asprey
Host; biohacking pioneer, discusses longevity protocols, testosterone optimization, and medical autonomy
Dr. Dave Rabin
Neuroscientist advisor to Apollo Neuro; taught Dylan about mind-body connection and neurological health
Lane Norton
Health content creator; Dave references friendly rivalry and donated profits from True Dark Glasses coupon
Peter Attia
Longevity physician; Dave references his fear-based approach to bioidentical testosterone
Frank Zane
Former Mr. Olympia bodybuilder; appeared on show discussing spiritual practices and flute playing
Laura Hoff
Expert participating in Antarctic expedition discussing human evolution and longevity
Dr. David Perlmutter
Neurologist participating in Antarctic expedition discussing brain health and longevity
Dr. Alberto Villoldo
Shaman and healer participating in Antarctic expedition on human potential
Ali Bogard
Expert participating in Antarctic expedition on resilience and longevity
Benjamin Rush
Founding father; Dave references his warning about medical autonomy in Constitution
Shailen Shaw
Kysetrex developer; Dylan consulted with him about oral testosterone replacement therapy
Monica Branch
Former Miss Olympia; co-hosted Mr. Olympia event where Dylan spoke
Christian
STEM Regen sponsor contact at Mr. Olympia; connected Dylan to biohacking community
Quotes
"I say it's cheating to put yourself at the level you're supposed to be at so you can actually be who you're supposed to be. Tell me how that's cheating."
Dylan Gemelli•Early in episode
"If you think I'm cheating, that's because you're losing. I will not ask for a permission slip to take care of myself. It's a fundamental innate right."
Dave Asprey•Mid-episode
"There's no such thing as cheating. Everything we are doing right now, including broadcasting this live so people don't have to fly here and drive here to hear us. Is cheating."
Dave Asprey•Mid-episode
"29 pounds of muscle in about six weeks. Yeah. With no change in diet or exercise... this is how powerful these are."
Dylan Gemelli•Discussing SARMs results
"The bottom line is, if you want to live a long time, you want to feel really good, you're not the most profitable consumer. So you got to do that work for yourself."
Dave Asprey•Closing segment
Full Transcript
Let's talk about some of your favorite sarns and my backstory for this so people know. I used a combination of these things, this was 10 years ago, on 29 pounds of muscle in about six weeks. Yeah, with no change in diet or exercise, I did tear ligaments in both shoulders because ligaments don't grow like muscles. I say it's cheating to put yourself at the level you're supposed to be at so you can actually be who you're supposed to be. Tell me how that's cheating. The idea of cheating is absurd. You know what always makes me mad? The people who talk most about cheating, they actually drive to the studio to talk about that. You mean we use technology to make life better? There's no such thing as cheating. And if you think I'm cheating, that's because you're losing. I will not ask for a permission slip to take care of myself. It's a fundamental innate right. You're listening to The Human Upgrade with Dave Asprey. Picture Antarctica, the edge of the world. Want to go with me this March? On the 8th through the 17th, a small group is boarding the World Explorer for nine nights at the bottom of the Earth. And you could be one of them. You'll leave the noise of everyday life behind and experience part of the planet few people ever will. Every day, we'll step onto the ice via zodiac landings, take polar plunges, and have conversations that challenge everything you think you know about human potential. You'll come back with a new perspective on everything. We'll explore human evolution, resilience, and longevity with legends like Laura Hoff, Dr. David Perlmutter, Dr. Alberto Violdo, and Ali Bogard. all in a breathtaking environment of ice, wildlife, and silence that sharpens your mind. This ship fills fast, and once it's gone, it's gone. And because you're part of my community, you get a $1,000 discount with code DAVE in all caps. Act now if you're ready for this once-in-a-lifetime experience. This is your moment. Don't miss it. Reserve your spot now at insiderexpeditions.com slash future. You eat clean, you train hard, you sleep well. But if the air you breathe is toxic, none of it matters. You take around 20,000 breaths a day. Each one delivers oxygen or pollution straight into your bloodstream. Most homes carry mold spores, VOCs, wildfire smoke, and microscopic particles small enough to slip past ordinary filters. Once they're in your body, they trigger inflammation, stress your mitochondria, and drain your resources long before you even feel it. That's why I use Air Doctor. Its ultra-HEPA filter traps particles down to 0.003 microns. That's 100 times smaller than what standard HEPA filters catch. Built-in sensors track your air quality in real time and adjust automatically when your environment changes. Plus, it's sleek and quiet. Clean air isn't optional if you want to perform at your best. When your air is clean, everything works better. It's why I have an air doctor in every room in my house and in my office. It's that important. Go to airdoctorpro.com slash Dave Asprey to breathe like it actually matters because it does. So Dylan, second time on the show. I didn't ask this the first time. Now, since that time, one of the things I appreciate about you is we might hang out in some similar corners of the biohacking world, but you maybe talk about it more than I do. the world of research chemicals and underground stuff. I mean, I rebuilt my health using underground stuff and I brought a lot of it out from the underground over the last 15 years, even some of the early peptide stuff and things like that. But the number of peptides has just exploded since I wrote my book. I've got a dozen of them I'm using right now. And there's probably another 500 that are interesting that I may or may not use at some point. And then there's all the research chemicals so where should we go first are research chemicals more powerful than peptides or are peptides more powerful than research chemicals or are they mostly the same thing well it's funny because peptides actually fall into research chemicals technically right so when i think of research chemicals i'm looking at sarms i'm looking at peptides and nootropics because a lot of those aren't technically legal so the the term research chemical is really just of legality, right? I mean, they're not illegal. No, it's a gray area. I've been, I got introduced into that market in 2012, right after I got out of trouble and went straight into a gray area, but it was more discussion based. And then going into understanding what is not for human consumption mean because they have to write that to sell it. They can't market it. And as a use for you. So if they market it and they put on there, Oh, you can get this amount of muscle or lose this amount of weight they're toast they can get fined or shut down isn't it so weird that glyphosate says not for human consumption but they spray it on our food and then we eat it yeah amazing isn't that funny how that works yeah and that's not illegal right huh but they maybe they don't have any regulatory control over what i put on my body because it's my body i thought kind of weird yeah that's where i've been living forever man yeah i i think we have some new friends at the FDA who are very peptide friendly and they're fast track friendly and there's value to an FDA approval of something. Yeah. Hopefully more value now because unfortunately the FDA has approved like an Alzheimer's drug that provably didn't work and they admitted that they approved it because they just needed a win even though it wasn't a win. Like that is not okay and it cheapens what ought to be a gold stamp of approval but I'm surprisingly I never thought I'd say this in my life. I'm more trustful of what I see coming out of the FDA now because I got to interview the commissioner and I asked him the hard question, like what big pharma company are you going to go to work for next? Wow. And he just laughed because I'm a surgeon. I never worked for big pharma. I took an oath I won't. And then the whole conversation was about like fixing things. And just the other day he's like, oh yeah, testosterone doesn't need to be scheduled. Like it's a controlled drug because some weirdo in the nineties used it wrong. Yeah. So like, let's be rational about this. And so he's fixed women's health with hormones. He's fixing men's health. I'm like, I think we have someone who understands how it works. I've never been more excited about that. I never thought I would say that. So anyway, I'm digressing a bit, but I'm hopeful. Are you? I am. I'm hopeful. I think there's always going to be some sort of control there in a way, but I think that we're moving in the right direction. Now it's just hoping we keep them there okay i found that once people use these and they see the efficacy and how they work and what they do and they have an understanding that they're not peds they're not performance enhancing drugs if they're used properly then they have multitudes of benefits what's wrong with performance enhancing drugs well nothing i mean nothing in my view but i mean everyone listening to the show it probably wants to perform better at some aspect of their life and if there's a pharmaceutical has little or no downside or a natural compound and lots of upside. Isn't that what ribeye is? But here's the problem. You and I understand what performance enhancing drugs mean, but in terminology out there, it's a steroid or something that does something harmful or illegal, so to speak. But even steroids, if used properly, don't have to be nearly as destructive as they have been. And I mean, I would argue that steroids have saved more lives by a hundred times because hydrocortisone or cortisol is a steroid they give you in the hospital yeah in fact i take a little bit of it almost every day oops helps with stress management yeah right we have these weird conversations where people think coffee and caffeine are the same thing they're not they think tobacco and nicotine are the same thing they're not and they think drugs are bad and the reality is every substance including water has benefits and it has a downside and putting them in these artificial buckets is for simpletons. Well, I ask you this question back to you. What's more harmful? A steroid like anivar, like an anabolic steroid or oxycontin? Which one's going to be more harmful? Which one makes more money? I got to think like, well, true. True. Exactly. I mean, you have to think like an overseer. Yeah, exactly. I got to wrap my head around. Or alcohol for that matter. True. Like, so if alcohol is legal, they have no say over research chemicals period i agree i always argued that marijuana was far more beneficial and less hurtful than alcohol i argued that for since i started smoking pot it's also not good for you no let's face it yeah all right are you into the enhanced games oh so so tell me your take on that oh i don't know i'm anything enhanced wise i'm i'm really for it as long as it's not going to kill you and the the spray that you gave me by the way nice it gave They give you a one milligram microdose of nicotine. And I had never taken any. Oh, no wonder you're having a good time. Yeah, I know. And your dopamine receptors are firing like no one's business. And running on low sleep and everything, but feel phenomenal. And it's, you know, I was amped to be here anyway, but that gave me an extra amp. Sweet. Thank you. And just a quick aside there. Nicotine is exactly what we're talking about. Yep. It's one of these things. It's not tobacco. and since 1986 we've had medical research published that shows it prevents or reverses Alzheimer's disease it's neuroprotective it uncouples your mitochondria it's been used for almost a thousand years to treat certain medical conditions but because smoking causes cancer people throw the baby out with the bathwater so I've been using nicotine for 10 plus years written about my longevity book and in low doses it actually has a net benefit like drinking coffee so it's addictive yeah well coffee is addictive three days of headaches and but you know what else is addictive sleep yeah exercise right water i live there with the exercise especially so i know man i know there's good addictions and bad addictions just like there's good and bad of anything exactly let's talk about some of your favorite sarms and my backstory for this so people know i use a combination of these things 10 years ago okay Put on 29 pounds of muscle in about six weeks. Really? Yeah. With no change in diet or exercise to the point that I was going on stage for Tony Robbins at UPW and I take out the shirt and I put it on, the button's all ripping. I'm on stage with this ugly blue shirt. I bought it like Kmart next door or something. I don't know, Walmart. Somebody bought it for me. But it was like, this is terrible because I had to go to an XL and I did tear ligaments in both shoulders because ligaments don't grow like muscles. So don't do that. But this is how powerful. 29 pounds of muscle is not trivial no no and that is a difficult task but can be done with the right ones yeah on the right diet now depending upon which one see when i started there were two well there i take that back there were three but mk677 is not technically a SARM my favorite but it's not sorry yeah exactly talk about that one first mk677 what is it it's a uh well it's just a really and and it stimulates that ghrelin it's it people use it to eat a lot i like it because it helps to get that hgh release and and i compare it to and oftentimes recommend it over using hgh because it's safer bodybuilders use it so they can eat a ton and a lot of people that struggle with appetite will shift to that which is great and fine when it first came out it was going for like three and 400 bucks a bottle nobody bought it it was mk2866 and s4 that was it that's all you could buy and then it started to evolve into gw501516 lgd 4033 and now we got s23 which is basically a steroid that is termed male contraceptive because it completely obliterates your natural testosterone but it'll blow you up wow so if that was just a word full of or a mouthful numbers for you. These are research chemical names for compounds that mimic the effect of steroids in the body. Yep. And what I was taking back in the day was LGD. I was taking GW501516S4 and MK677. That was the other one I took back then. Yep. And just if you're saying, well, what are all these things? These are things that are documented over the last 10 years that have massive improvements in certain aspects and they have some risks. Yeah. And for people who have muscle wasting disease, people who are really unfit, you can throw a switch more powerful than peptides with these research chemicals. Yeah. And let's talk about MK677. So I don't know if I've shared this on the show. I was very fat. I've had all kinds of problems with my health and I've reversed them all. and my body oh 10 years ago was making zero growth hormone and i had this tested with the glucagon test like the proper test not just looking at insulin levels and insulin like growth factor so working with the medical doctor i went on human growth hormone physiological replacement not the kind of stuff to get jacked did it for five years like oh if you go on this you can never do it again like peter atia fear style and uh like he's the guy who's afraid of bioidentical testosterone so like but my body has none so then i said you know it's time to taper off it and i did and my growth hormone levels were fine i rebuilt my biology so i turned on my own growth hormone then last year i went through a period of extreme travel and some other biotoxin stuff and my growth hormone levels plummeted again so i could have taken growth hormone i could have taken the peptides that caused you to do it like ipamoralin yep cjc or i could have done mk677 so i did mk677 just for last three months and well you know my levels of human growth hormone went back up to normal that's right no doctor's going to tell you this actually you're working with me and my team at unlimited.life we would tell you to do that but most doctors aren't going to tell you to do it no we can't prescribe it now we can mention it's possible then if you do it on your own that's your own thing that's right and and oftentimes because i was with the bodybuilding sphere for however many years and i i started bringing that up and i used to get the hardest time from the meatheads oh it's not the same it's not the same and then now if you go and talk to anybody that owns a research chemical site that's always a top seller yeah because everybody knows now and i just used to get just people beating my head down over it it's really funny because when i started the biohacking movement i've been running a longevity non-profit group in palo alto for i don't know six years i was also in the gym a lot right and these bodybuilders know stuff longevity people should know and vice versa. And then the neuro guys and then the meditation guys, they also, so I wanted to bring it all together under one umbrella so we could at least talk. That's it. They all go together. If everybody would just stop thinking they know everything or that there's not alternative methods. Oh, you mean like the Lane Norton effect? Oh shit. Here we go. So I was talking to BioLane's mom the other day. I love health bullies. He's my favorite health bully. I don't get it. I just don't get it. I don't get why people have to do that. I don't either, but man, it's so good for sales. Because last time he was like, Dave, you're wearing piss stained glasses and I didn't like something you said. And I just reposted it. And then I ran a coupon code for True Dark Glasses. I remember. But here's what you don't know. So because I ran that and it was sold like tens of thousands of dollars. So I'm taking the profit from that and I'm donating it in his name, in Lane Norton's name to a nonprofit for victims of childhood bullying. I love it. We're just going to say it like it is. So Lane, if you're listening and we know you are, and we know your mom's listening too. I just, I just got to say, man, like take a deep breath, maybe like make out with Peter Tate, whatever you're into, man. I'm not going to judge you. Right. Like you, you are enough. You are enough. I'm sorry. I got it. No, but there's, I'm glad you brought that up because, you know, I went through that for years when I was doing what I was doing. I had this one side that absolutely loved me. And then I get guys like him. Yeah. Oh, you're not 300 pounds. So why are you talking about steroids and how to how to use them properly and everything Oh yeah because the guys that are 300 pounds that don know what they doing that just take everything under the sun and that are killing themselves that who you want to listen to Yeah You can really harm yourself And I'll just say, if you're angry all the time, either you have an imbalance in your biochemistry, could be too much tea, could be a bunch of other stuff, neurotransmitters, or you just have a lot of childhood trauma and they're both imminently hackable. Right. So let's assume there's someone listening to the show like i have research they don't know what we're talking about yet so completely unknown let's say that this is someone between 40 and 60 and i want an answer for women and i want it for men that are different absolutely okay what are the two research chemicals that are most likely to make them lose fat and gain muscle i'll tell you where i like is s4 because men and women can both use it and it has this really nice effect of muscle hardening which i'm all about the aesthetics right and lean muscle gain little suppression for men women don't have to worry about testosterone yes exactly and very few side effects there's a vision thing that people panic about and it's very simple to overcome okay so what happens is is let's say you use 50 milligrams of s4 standard dose yeah uh yeah you can take it either capsule or like the the liquid okay and so So basically, if you are in a dark, like the setting we're in now, and you look at this light and then you look, you're going to see this yellow flashing. I thought it was great when I was driving a car the first time and I saw it. I was living in Maui and they had these non-lighted streets and I was like, oh, this is crazy. So it's not so bad. But other than that, very little side effects and the muscle hardening, it blew me away because I'm already pretty vascular, but I was seeing veins across like a rope around my abs. I've never done that. I have some ab veins most of the time, but like, yeah, they're a little bit lower down. But if you're getting upper ab veins, that's insane. It was insane. What's your body fat percentage? Right now, about 7.2 last time I checked. I stay pretty 6 to 8 range, but it gets too low. It's unhealthy. Yeah, I was getting down to 6.5. I didn't feel as good. It was hard. I think I'm around 7.5 right now. Probably, just seeing the skin. I got a lot of extra skin from when I was fat, too. So that kind of changes things. But you know what? I always say when I looked my best, I felt my worst. Every fitness competitor, especially women says that. Yeah. Yeah. Like I, like I have no libido. I'm tired all the time. I'm anxious all the time, angry all the time, almost like a vegan. And it's true though. It's true. You know, I didn't ever mean to do vegan, like never intended, like no fear of, of, of eating animals or anything like that. But I did looking back on it. I was doing that and I was the most miserable I've ever been in my life yeah me too 18 months of just hell and first three months I was like I got the glow and the glow is anxiety to go hunting and like oh but don't you feel like you just I for me I couldn't stay focused on her 20 minutes no it makes you flighty yeah I'm grounded yeah yeah just all over the place I start working and I get up and walk around or do something and go oh shit I don't want to do this and you get like muscle pain and joint issues I got autoimmune issues it was terrible yeah that's why I see these young people who get into bio, I go, I'm going to go vegan. I'm like, man, there's no health reason to do it. There's no animal cruelty reason to do it because you kill more animals cutting down your wheat and soy than you do from eating a cow. That's right. Right. And there's no environmental reason to do it because we need poop as much as we need milk and beef. So I'm like, I don't get it, but I did do it. And so I've felt for that. And you're burning out like 10 years of useful life if you don't repair it. I agree. And same with like the protein powders and everything that are pea protein and rice protein, I won't touch them, man. You know, I think there's a role for human kibble. Yeah. I love talking to you, man. I'm trying to be polite and all that stuff. I just got, you know, I just got to say it like it is. No, I went, when I rewatch our show when you came on mine, there's so many things that I rewatched. You have the kind of humor I enjoy. I enjoy that Chevy Chase 1980s, like dry humor that you have to be really smart to get. Are you just saying I'm old? No, no, no, no, no. I feel triggered right now. I identify as triggered, actually. That's even better. That's what you identify? Yeah. And you know, I was laughing here because I had a feeling at some point you were going to ask me when I changed from bodybuilding to biohacking. And I was like, I transitioned. And I was like, man, I can't say. I started that clip. There'd be a ringtone, you call me. But I got it now. You said, I transitioned. And I was like, oh shit, he'll kill me on that one if that comes up. When did you move from bodybuilding to biohacking? So I was I got my big opportunity to actually speak with doctors and practitioners at Mr. Olympia two years ago. And what's crazy is I actually I went up there. I tore the house and I was prepared. Yeah. Fifteen years of preparation. I was prepared. Well, I got asked to co-host with Monica Branch. She's a former Miss Olympia. He was being sponsored by STEM region and the Mr. Olympia. So when I met Christian over there and them, they watched me speak and talk. And we hit it off. So I made all these contacts. I was all excited. Went home, got COVID immediately. Oh, no. Yeah. So, and I'm a spiritual guy. No, not everybody is. That's fine. But I'm all very open about that. Can we judge and shame the non-spiritual people? We can, sure. I don't know if it goes well with the spirituality. I'm just kidding. Well, so, because I went to the gym when I got home because I can't miss a day. And I got done and I called my wife. I said, I'm going to CVS. Something's wrong. Got a COVID test. Anyway, I couldn't get out of bed the next morning. I normally do this woe is me thing when I'm laying there like, why? And I decided, okay, God, I'm going to trust you, right? I don't know why. And I'm laying there and I can't move. And I started to look at Stam Regen on Instagram. And then that's when I really found you too, because I was going through all their stuff. And I said, I'd heard biohacking before and I didn't know what the hell it was. and I'll tell you what, three hours of me inundating myself with nothing but info. And I called my wife in and I'll remember this conversation. I get chills. And I said, you're going to have to trust me. I have been, I've been miserable talking of all the stuff I've been doing. I'm unhappy. She knows it. I said, we're making a move. This is where I know I'm supposed to be talking about this stuff. And from that moment on, I started, I went to eudaimonia with STEM regen and that was my first conference. And from then I started the biohacking type of podcast and here we are a year later welcome to the team biohacking man it's where it's at it's funny because it's really change the environment around you and inside you so you have control of your state that's it is your cookware actually poisoning your food most non-stick pans contain pfas or forever chemicals as they're known manufacturers add them so the pans will be slippery but get this a recent study found a single scratch on a non-stick pan can release about 9,100 plastic particles. Then you get to eat them. And those chemicals don't break down, and your body stores them. And studies show they can contribute to immune problems, insulin resistance, even cancer. A company called Our Place makes high-performance, toxin-free kitchen wear, and I've been using it for years. Their products have zero forever chemicals like PFAS and PTFEs. You can cook amazing food without wondering what's in your pan except for what you're cooking. Their cookware set will upgrade your entire kitchen and your meals. The set includes two multifunctional always pans and two perfect pots in many and full sizes, and those replace a bulky, expensive stack of cookware. It's just four pieces, and it lets you sear, saute, fry, bake, boil, roast, steam, and whatever else you can do with a pan. Our place designed their products for performance and long-lasting quality, and I've been using my frying pan for about six Sears now and it's still perfect. So stop using Toxic Cookware and upgrade to Our Place today. Go to fromourplace.com slash Dave and get 10% off everything. Plus you get a hundred day risk-free trial and free shipping and free returns. So you can just give it a try and there's no risk. That's fromourplace.com slash Dave. This upgraded my cooking. Your body makes less stem cells every year. If you ignore that, you start recovering slower and you age more quickly, and it starts earlier than you think. By your 30s, the number of circulating stem cells you have drops hard. Stem cells handle repair, recovery, and tissue renewal, and fewer stem cells means fewer repairs. Maybe you feel like you do everything right, yet soreness lasts longer, injuries linger, and you don't bounce back the way you did in your 20s. Stem Regen targets the issue at its source. Every time you take it, it signals your body to release 10 million of your own stem cells into circulation. Stem Regen also directly supports circulation, so those cells can actually reach your tissues that are stressed. And these cells already know what to do. They respond to damage. They support repair. Stem Regen helps your body do the work that nature designed it to do. And I actually use it and I actually send it to my parents. So if recovery and longevity matter to you, act now. Go to stemregen.co slash Dave30 and we'll give you 30% off your next order. Bodybuilders are some of the best on earth at changing their state. The mental state, sometimes you need to do some work, but even guys like Frank Zane came on the show. That guy is a semi-enlightened being. He's like, oh yeah, I play the flute for an hour a day just for my interview. I'm like, this is the most interesting guy ever. And so like the old school bodybuilders who've lived, most of them have an incredible spiritual practice as well. Yeah. Because your physical body controls your emotional and your psychological, even your spiritual body. They're connected. You know what I realized is I learned about peptides and SARMs in 2011. I've been doing and tweaking and doing these things to myself forever. It's not polarizing. There's nothing crazy or strange about the term. It's very simple if you just understand what it is. Yep. And once I, I watched a lot of your stuff and a lot of other things there and I, I listened and I told you before the struggles I had with eating and how I was under eating. And I, I took so many pieces of your diet. I put a little bit of what I was doing. I wrapped it together and I'm telling you, man, my whole world just opened up. You know, happy that makes me like that. That's why I did it. Cause I was feeling the same way. I was wrecked and I just couldn't unpack it. It took a long time to make that diet and it's helped a lot of people. And you don't have to, it's not the same for everyone. It's like, do these for most people. These are suspects. Like you got to know if you're nightshade sensitive, you will get arthritis and autoimmunity from eating chili, which is my favorite food. And I have the gene. I don't eat chili anymore. It's not that hard. But if I didn't know, I was just in pain all the time. And I was reading it and some of the things when there were things, all the things I was eating. And I was like, you know what? I'm just going to do it. And if it doesn't work, I know how to fix it. I know I can go back to living in hell again if I'd like to. And I'm telling you, I went in that kitchen one day because I'm the type of guy where cars just show up. Shit just shows up. My wife is used to it. And I walked in there and I said, listen, we're going to go to Whole Foods today. We're going to buy all these foods I said I didn't like. I didn't even know if I liked them or not. So avocado, salmon, fresh grass fed beef. And now I'm eating every kind of beef under the sun. And like now when we're done before my flight, I'm going home. I've got avocados ready to, they're chopped. I've got all my stuff cut up, the eggs. I eat, I was eating 1,600, 1,700 calories a day, like I told you. Wow. Now I'm doing 3,000. You feel so much better, don't you? I look better too. Yeah. But I was eating like 20 grams of fat. Now I'm doing 130. And you're at least as lean as you were before. I'm leaner than I was. But fat makes you fat. Right. I mean, Lane told me. Right. So does a lot of dipshits. Yeah. it's just not how it works and when i was really my heaviest gym rat times i was my early 20s i was on a low fat low calorie diet 90 minutes in the gym six days a week without fail even if i was sick like if i could walk i went to and couldn't lose a pound right couldn't lose a pound and felt like crap and all that stuff and i just was what is a calorie measure energy yeah and you know who's even worse than, than a lot of men is women. The number of women who are starving from their freaking salads all the time, like, please eat a steak and they eat a steak and like their eyes light up and like, Oh, and they make like happy sounds. And if they do it for a week, they're like, I'm not cold all the time. And I feel so much better. My anxiety is down. And so this like fear of being seen eating, we just have to do away with that. Like eating is a sacred act of nourishing yourself at every level. I, you know what? I wouldn't touch a salad if you paid me. I won't even go near them. I don't touch them. And I'm telling you, even arugula, you want to touch that stuff? Well, I'll eat that. That's it. I'll touch. Arugula and lettuce, I'll touch, but not for nutrition, just for like, oh, that sounds crunchy. Yeah. There's no point to it other than that. You know why I get angry now is all the years I missed of cooking in butter and, and thinking that that was going to make me fat or gain weight. And I mean, sometimes I'm not even going to lie to you. I take a little bite off the stick and just eat it. I mean, I do because I miss it, you know, and I literally cannot tell you how much my whole life changed and opened up. It's just insane. This makes me so happy because I, all the content I was, if someone had just told me this when I was like, save me a million dollars, it's like two and a half million dollars on reverse of my age, but the first million was just to get well. Right. Right. and if I'd have just known. So the fact that you could throw the switch that fast? I'm that type of guy where if I want to do something, I can just do it. But I have to make myself do it. See, we talked about prison. One of the things in prison is your whole life is based around routine. And I've already been a structured guy my whole life. And so one of the things I'm good about is, okay, when I go on a trip like this, I'll say, well, things have to change and I do it. And then I go, well, I just did that and I was fine. And then I'll go home and do it. And then you'd make a new routine. It's very simple. Even if you're structured, you just got to try, you know, and we get into our own ways. I've been a nutritionist 15 years and I was doing the low fat thing going against what I was coaching. Wow. Because I'm the exception. That's what I was telling myself. Yeah. Only nobody's the exception. Well, I don't know if I agree with you there. like you look at these epidemiological curves and they always set stuff for like the middle yeah but if you have the weird genetics there are people who should not be eating more butter true because of their APO yeah for double all that kind of stuff so eat more olive oil right people with no gallbladders but there's always like quarter cases but there is no one who's always the exception that's what that's that was my thing yeah because I I had myself convinced of that and didn't even try. Yeah. I just told myself that you got to try. So many listeners are going to benefit from that because, you know, the worst thing that happens if you've tried something new for a week or two is that it won't work. Yeah. Well, that's what I said. I know how to lose weight. Yeah. If it doesn't work, I'll just make it work. Yeah. You know, I'll cut this out. And that's another thing that I want to bring up is a lot of times you try to do everything at once, then you don't know what's working and what's not. Yeah. You know, and that was one of the things I dealt with with bodybuilders that wanted to take five things at once. And I'd say, well, then how do we know if something, if you have a bad side effect, I don't know which one it is. Yeah. Because many of things have the same kind of problem. So I am a, and I'm so dialed in with the diet and everything. I'll put one thing in, see how it works, try it and then that's it, you know. We're kind of the opposite that way. So when I first started getting really serious about losing the weight and fixing my brain and all this. I did all this research. I fired my doctor who told me that vitamin C would kill me. Literally, Palo Alto Medical Foundation. Thanks, guys. Yeah. And it turns out, you know, if you're doing 100 grams orally every day, you'll probably get oxalate toxicity after a while. So there are, you know, everything has good and bad. But vitamin C is not going to kill you at normal doses. I order like 10 supplements. I go, I'm going to try each one for a month. And then I looked at my list of things to try And I looked at the number of months in my life I like I not going to even try everything for one month And so then I just thought about it Like it impossible to do that So I going to pick a goal and I going to do everything that I can afford all the same time that logically lines up to reach that goal. And once I reach the goal, then I'm going to take some things out because usually life is a recipe. Yeah. Right. So if you were to take this approach if I'm trying one thing at a time, like I'm going to invent bread. I baked the water. I baked the yeast. I baked the flour. Ah, there's no other thing as bread. So sometimes you got to fix your thyroid and your testosterone at the same time to get results. Yeah. So my approach is, you know what? If you want to get a goal and you're not a research scientist trying to isolate variables effects, who cares? Do all of it, do all of it this month and you set aside $500 or whatever your budget is. Like I'm going to go in. And at the end of the month, like my brain is so good my eyes are shining my skin is better i've lost you know 20 pounds and something in there is working right right and then okay next month like don't only do half of it right and this is my computer science mind it's like bubble sorting is what we call that so the thing is though getting the results without undue risk is the goal not figuring out which one it is yeah because i have the most expensive pee on the planet right now i'm pretty sure my plants love it right it's fine I love it. You know, I did that when I found out that I had plaque in my arteries. I did everything. Yeah. Everything. That's interesting. And did it work? To a point. But then I started to get some higher liver values from all the niacin, for example. And I knew it and I cut it out. And then I started just taking minus and some things out. And then I found what really worked together for me personally, that wasn't causing me heart palpitations or making me like not sleep, for example. So soft plaque or hard plaque? hard okay so you were calcified plaque calcified that's actually less dangerous than soft absolutely absolutely and you got that down i have what i feel is pretty reversed it now because i went in i i had the calcium score first step one what was your score 120 oh dude freaked me out then i found that i had an extremely high lp little a 330 that's very high too hacked that down to 90 which i was told was impossible long story short i went to mayo clinic yeah supposed to be the best of the best of the best which was what i was told and i went in there with the idea that i wanted to use rapatha pcsk9 inhibitor i wanted to use vasepa and i did not want to use a stat and they told me that prescribing a pcsk9 using vasepa was bad practice this was their words and that using a statin which i know will increase my lp little a yeah and i'll i'll leave the other stuff out right now. That's what they wanted me to do. There wasn't enough research on LP little a, which I found crazy because I had inundated myself with research. So I got in a fight with my mom and my wife on the way home. And I said, who are you two? You're listening to these morons. I'm going to do what I want to do. So that was the start. I did the niacin for quite a while, but that started to make me feel not so good, but it did drop my LP little a. I was doing grams of flush niacin. That's a lot of niacin. Yeah, it's too much. But pomegranate juice is another one that can reverse plaque. It can. And anyway, I had a different episode of like high heart palpitations, which I panicked, which I think was due to a loss of electrolytes. Yeah, most likely. And I went in and they did the catheter up my arm because I had a CT angio that said 35% blockage. Well, then this was a year later and he said, I don't see any plaque in there. You have no blockage of any kind. And I was like, okay, well then I found I had a low ejection fraction, which may have been due to the eight times I've had COVID. And let's explain that for people. So ejection fraction is how much blood can your heart move in one pump and healthy, strong, young animals can go from chill to in one heartbeat, slam that blood through. But people who do chronic cardio exercise, they train their hearts to actually be weaker by having a small ejection fraction. So I have a very large ejection fraction. My cardio of 90 to 120 minutes a day for 20 years probably hurt that. So what happened was I got put on Jardians and I was put on Entresto, which is a bad move considering my normal blood pressure is like 96 over 62. Oh, you're a low blood pressure guy. Yeah. Yeah, that's going to mess you up. That's why your heart was racing too. Yeah. So I stopped that. Anyway, within three months of Jardience at a low dose, D-ribose powder and high dose ubiquinol, which I came up with, I went from 44 to 50. I have to go back in again now. So 55-70 is normal, as you know. I want to be hopefully in that 55-60 range. Wait, which metric? 55-70? 55-70. On your ejection fraction. Yeah, ejection fraction. Yeah. And so I went from 44 to 50 in three months. So good. I didn't realize I was training in zone four so long for so many years. Yeah. Bad. Yeah. I used to do long distance cycling when I was overweight and I even did a couple of races. It's not really a great idea to race when you weigh 280 pounds because somehow going up the hills is not easy, but it was, it was not a productive thing to do. No. And I've, I'm a big fan first of high intensity interval training 15 years ago. I'm like, this is better. And now I, I just get re-hit and I've never been healthier. Yeah. So that's something that, that for, for listeners, there are a class of like 1970s researchers and even some longevity doctors that like zone two is where it's at. You got to do zone two, eight hours, eight hours a week. I have teenage kids. I have nine companies. I have this podcast and I have friends. I'm not doing eight hours of zone two. That's insane. Right. You could also like fast in a monastery for three weeks a month or something. It's not going to happen for the vast majority of people. No, it's difficult. So you got to find out how to do it in a meaningful amount of time. You know, I have found, and I used to just brown upon it. I walk on my non-workout days. I do four or five miles of walking every day. And my workout days, I do three. I do it every morning. And then after I eat, I go bike about 10, 15 minutes to move. I have found that to be more productive for me because I don't know. you do feel heavy after you right after you eat and you walk and so i do the biking and i do it steady not i'm not racing just on the path enjoy the scenery i'm by mountains now and just feel free clear my head say some prayers come home get right back to work and we call that movement it's so good for you and it's sunshine too right yeah you're doing it without sunglasses i'm guessing oh yeah good deal yeah that circadian exposure too yeah i i listen and every time i give a talk, I preface it. I'm not saying do three hours in the sun because people freak out about the sun. You got to have the sun. The sun is one of the most underrated nutrients there is. One of the reasons I moved to Austin from Canada, I just, I'm not feeling good. And I came down and I got much healthier. And some people say, oh, you get all the vitamin D you need from the sunshine. What's your take on that? I think you get a good amount, but I still, you know, I like to supplement and eat good foods and everything. I think you get a good majority though from the sun. I think without it is the problem. Well, if you're taking vitamin D, you still need sunshine or at least UVB to activate it. Yeah. And I did a test a while ago. I lived in Hawaii for six weeks and I said, I'm gonna quit taking vitamin D. I'm gonna get my three hours a day in the sun. You know, I got some sun damage from it. I had a great tan and you did all the, I actually never burned because I didn't know how to eat right, but I did just get some sun damage from it. And I measured my levels, there were 36. really yeah i also have genetics where i don't hold on to vitamin d and i use it real quickly and so there is no way i'm going to get it up there without self-moans and sunshine yeah i agree i lived in maui yeah so when i got out of prison i got sent to maui because my parents live there okay and i took melanotan too i love that stuff dude i was so dark i was embarrassed because you take it and then you go sit you're supposed to go out in the sun a little bit not in maui man Bad idea. Bad idea. I was so ashamed of how dark I got. I had to stay home a couple of days and get off of it. Cause you're like too tan. It was, it was really bad, man. My wife's from the Philippines and I was way darker than her cause I met her. That's funny. So you were, you were really dark. It was embarrassing. So melanotan is a peptide you can take that stimulates melanin in, in your skin. And it's really good if you just do one or two courses beginning of summer, cause now you have built-in sunscreen. So last time I used a round of it was at Burning Man. So I just injected in the morning and walked around naked for an hour and I had a tan for the rest of the week. It was great. Increase in libido. No tan lines. Yes. And the libido increase was pretty damn sweet on that too. So let's talk about that for listeners. So Melanotan has a side chain called PT141, which you can buy separately. Right. You take Melanotan or studies also show if you just sunbathe, it makes you horny. It releases nitric oxide, but there's a libido that's separate from nitric oxide. So you do melanin 10. I remember it was like when I was 19. Yeah. Oh, like, yeah, that is noticeable. And at the time, there wasn't a ton of literature on that part of it. And so it caught me. I read it, but it was not really talked about. And I was like, okay, okay, this is amazing. And I was pretty, I was 30 at the time. You just got out of prison. Yeah. Oh, yeah. Yeah. So I was like, okay, this is great. But you know what, Dave? I tried it three different times, different companies, and I know it was good. Lowest dose, and I couldn't take the nausea for me. It made me too nauseous. Some people get that. Yeah. And melanotan one probably has better cognitive benefits. It doesn't darken as much as well. So that might be a better one. You're talking about you tried melanotan or PT-141? Melanotan. Yeah. And some people get nausea from PT-141, so you titrate the dose down. Yeah. And there's other libido hacks that are out there I've talked about in other episodes. I took it right before bed to try to help. with the thing and it just made it just as bad. I would get so sick. And not only that, melanotins is a circadian hormone. You take it in the morning or maybe at noon. I know. And you take it at night, you're telling yourself to stay awake and you're going to be pitching a tent all night long. You're not going to sleep at all. You can't even roll over without breaking something. But there was, like I said, it was at that time, it was like, that was more of a trial and error time of stuff. And knowing what I know now, I was like, man, everything I was doing was backwards oh this is so funny yeah but it was really really there was like seven peptides you could choose from at the time yeah it was it and it was really just gh ghrh and and like so ipamorellin hexarel and sermorellin cjc and melanotan there really wasn't anything now there's thousands yep and i'll talk about a couple and i want to know your favorites yeah tell me about your newest ones so my favorites is motzi apv i like c max and selenck i'm a i'm really kind of gotten more into the understanding of the importance of the neurological side yeah and i've really done more of mind body connection that's thanks to dr dave rabin he's my boy yeah i'm an advisor to apollo neuro yeah i love dave yep and uh so you don't know this i'm on the advisory board now too with dr dave oh right that's right that's why i'm wearing this right here. But he taught me a ton. And I put together that understanding now of how important the mind is to actually affect our fitness and our health. And honestly, I put that higher understanding now how drastic like my anxiety was and the stress and what everybody else goes through now. And piecing that together, I feel has made me a more complete knowledge base for others to help stimulate myself. And I'm sure you would agree on the neuro side. It's incredible. it's really funny uh some doctors will talk about muscle mass is the most important thing in vo2 max you know i'm talking about yes so here's the thing though studies actually call it with muscle strength more than muscle mass which is based on neural drive you look at the shaolin monks who are doing these incredible feats that you can't do or i was gonna name who's the guy who goes to gyms and looks like he's a janitor oh shit i i don't know his name but i love his videos he's great uh i'm forgetting it's i'm drawing a blank but i want to call him pavel but that's not his name no but i see what i see his videos so there are these guys who are massively stronger than people with twice the muscle mass like that's interesting so it turns out strength is more important than mass but you want a good amount of mass yeah that's important and that's because of neurological health and because of mind-body integration which is just terribly important And then on the VO2max side, it turns out all of the studies that measure VO2max were not actually measuring VO2max. They're inferring it with a broken algorithm. So the data is all junk, but you can still stand there and say, you know, I'm a longevity doctor who says you can't live longer. You should do a lot of VO2max training based on studies that aren't real. And you should have a lot of muscle mass ignoring strength. And I don't think that's how it works for longevity. I really don't. And I could be wrong. and I'm willing to be proven wrong. But I find that, look, there's no doubt the importance of muscle and sarcopenia is a very real thing. But getting too big for too long is very unhealthy. It's too much strain and stress on your heart, ligaments, joints, like you were talking about earlier. There's a fine line. Yeah. And I think a lot of like the bodybuilders, especially they don't have any concept of that long-term. All they care about is getting big right now. They don't worry about tomorrow or the future and carrying too much weight for too long and eating too much is not good. It's not. No, it's actually bad for you. And even when I was stress testing the Bulletproof Diet before I wrote the book, I went 4,500 calories a day. That's high. And I cut my sleep to usually under four hours a night. I'm like, I'm gonna gain like three pounds, but the calorie math is gonna say 20 pounds. And I actually got leaner and I felt better. And I just kept going for like a year. It was not good for me from the longevity perspective. But like I can do this. I'm kind of liking it, except I just got tired of just forcing myself to eat more steak and butter. It's hard. Like once you get over a certain point, man, it's like forceful to eat that much. You can smoke pot all night and make yourself as hungry as you want. It's still hard. They just it's like you just don't want to do it. No, I found for me like that 3000 range, even though I'm on paper, it says to eat like 3600 to maintain for my output. I can't do much more than 3000. Yeah. It's hard. And then it's not good. It doesn't feel good. You feel heavy and, you know. And overeating any kind of calories, even relatively good ones. Actually, I've never seen a paper that says that makes it by type of calorie, but we just know overeating in general is not good for longevity, right? But also under eating isn't good either, unless you're one of those, like I eat 35% less calories than I need and I'm miserable all the time. I don't think that's a good plan either. No, I know. It's funny because when we were talking about the fat, you know, does it make you fat and everything? If I was to tell you the five foods I can't live without, they're all like higher fat. I have eaten unlimited fat. I eat butter. I eat sheep's cheese and sheep yogurt and I eat tallow and I eat two ounces max of olive oil every day. And I've done that for 15 years. Wow. And my blood is just fine. Yeah. My HDL went up 40 points 40 the protective cholesterol yeah who would have thought and your your testosterone went up too absolutely yeah i mean i'm on ert but you know it's still it's last time i checked it i was like what happened here it was way too high and i take it like 100 milligrams a week and i was like well over a thousand and normally i'm like seven eight hundred right around there there's nothing wrong with being a little over a thousand no but i i was like whoa what happened here i just got prescribed kaizotrex I going to try and see how that goes But I have waited about a year now to see research and data on it But I sick of injecting now for so many years So I'm going to give it a shot. I've been on Kaiser Trex for the last 18 months. Really? Yeah. And guys, that whole episode, DaveAsprey.com slash testosterone. I'll tell you about it. Yeah. And here's the deal. I have been injecting testosterone since I was 26 years old. Because at 26, my longevity doc is the only one in the Bay Area. was like, uh, Dave, I hate to tell you this. Your testosterone is lower than your mom's. And my mom was his patient. And well, that will explain why I'm really fat. Yeah. And there's toxic mold involved and sleep disruption, all kinds of stuff. So I went on it under a doctor's care and not physio, not above physiological. I've been on it most of the time. I went on for a couple of years when I was developing the Bulletproof Diage and I could get myself up to 700 if I did everything right. But for me, a thousand is the right number. Yeah. And, and guys need to understand this. there is no right number. Your range could be anywhere from like maybe 500 all the way up to 1500. And that might just be your normal. Right. And unless you're really healthy as an 18 year old and you measure the numbers, you're never going to know. So you kind of have to see how do I feel on these? Yeah. And the reason this new oral testosterone is interesting is if you inject testosterone, what is the side effect? Well, high estrogen for one, you're going to crush your FSH and LH, zero, gone. So that's going to be a problem. If you do too much, there's potential heart risk. I mean, you got to go heavy on it, but that's definitely a problem. But when you shut down that LH and FSH, that's a lot of the reason for the fertility issues. But there's, I see high blood pressure. I've seen it all. And you know, the one thing you didn't mention is your balls shrink. Yeah. Oh yeah. And that's because LH and FSH get suppressed when you inject testosterone. So guys, I'm just going to tell you, I have, at least I had small balls. Right. And it turns out they're harder to kick. I don't know why it matters, except you need to have LH and FSH. That's right. So most guys who go on testosterone experience ball shrinkage unless you take the things that block that effect. And there's lots of ways to do it with pharmaceuticals or natural substances. by switching from injectable testosterone. And I've injected it so many times in generally the same spot that when you do an ultrasound, you actually see fascial disruption from 500 needle punctures into the muscle. So I can do better. So Kysetrex is this oral form and you take it and it doesn't cause ball shrinkage. And you get a brief peak every day. When you and I were injecting once a week, you get a big spike and then it goes down. But testosterone is also circadian. That's right. So I think it works really well. I notice it. And, you know, the cool thing about having an oral testosterone pill, if it's date night, like, I'll just have an extra. Yeah. And then it hits you in, I don't know, I forget, it's an hour or two. But you're like, all right, I'm at my high testosterone right when I needed it most. That's right. And it's just another thing in my supplement stack now. It's a lot less work than traveling needles and all that crap. Oh, I hate it. You know, I put myself on it like a moron, which I don't ever advise, but I did exactly what I don't advise. You do too advise. Yeah. I started it because I ran steroids. And then instead of running a post cycle, I just stayed on it. I've been doing that for, let's see, 12 years now like that. And then I found out about Kaisotrex right when it was coming out, before it came out. And then I just talked to Shailen Shaw about it several times. A show a couple of times. Yeah. And he's great. And he said, I'm going to get you on it. You try it and let me know. And I just got it. And I'm giving that a whirl now. It's funny. people have a lot of judgment about testosterone, even though it lowers all cause mortality. I know. And to have adequate testosterone and just about no one alive has adequate testosterone because of the stuff we did to the environment, because of lighting systems. Thank you. So like, if you want to show up in your life, testosterone drives dopamine, dopamine drives motivation, new things that matter. It's important on your workouts work better. This seems like a low pain way to do it without the downside of the way I did it before. Yeah. And there's some else. I'm just going to say this right now. If you're 19 or 29 and you have no money, that's actually how it was when I was 19 to 29. Actually, no, I made $6 million at 26. I just lost it when I was 28. So by the time I was 29, I had no money. So I had a brief period of wealth in there. But the bottom line is, you know, when I was 22, I was sharing a one bedroom apartment in a slum. Yep. Trying to pay for college. Right. and I welded Toyota truck frames and scooped Baskin-Robbins ice cream and did all the stuff right if you run an at-home lab test right and there's plenty of those online one of my companies does it Axo.health but you can get those anywhere and it's going to cost you a couple hundred bucks and your testosterone levels are really low do the biohacking stuff to raise your levels if they don't go up there is nothing wrong morally with you deciding to treat yourself like you don't need a permission slip from your government your insurance company your doctor, from God, from anyone. You get to do that. And if you put yourself on it, don't be an idiot, right? Do the work. And I would prefer you see a doctor. And if you don't have the money for a doctor, I would prefer that you be healthy. And that's the world we live in right now. And it's okay to say, you know what? I did all my research. I asked a bunch of people, I did the best diligence I was capable of. And I ordered this drug from India and it cost me $32. Would it cost me $600 by the time I went to my doctor, which I don't have covered by insurance and blah blah blah no like you gotta live and yeah just sometimes people do that and and and it's okay and it's not as good as going to a doctor and maybe we'll build a system where like health care becomes affordable again yeah maybe yeah and you don't have to beg for permission to get what you're going to get anyway you know my health insurance went from for me and my wife on a company thing from twelve hundred dollars to eighteen something in this this trans the transitional year here and it was a little bit lesser of a plan that's a house payment i know in a lot of the country it is yeah it absolutely and what value do you get from it shit i will tell you if they say bill insurance i'm like no i'm just paying yeah and most of the doctors that i see and i a partner in a medical thing but none of them take insurance anymore because insurance companies are useless i know unless you have a massive car accident it's useful so i oftentimes advise people, you know what, don't be like, oh, I can't get it because it's not, no, that's not how it works. Just buy catastrophic healthcare insurance and everything else, put it in your FSA and FHA. Yeah. One other thing I was going to say about the testosterone. So I will get this concept of it's cheating. Now that's whether it's an athlete or for whatever the case. And I say it's cheating to put yourself at the level you're supposed to be at. So you can actually be who you're supposed to be. Tell me how that's cheating to make yourself perform how you're supposed to perform. So really all I'm doing is putting myself at the state I'm supposed to be at. So it's cheating. How? The idea of cheating is absurd. I agree. You know what always makes me mad? The people who talk most about cheating, they actually drive to the studio to talk about that. Yeah. They're using a car. They should be walking. Right. Like seriously, the car is cheating. Oh, and so are the shoes. So take those off. Oh my God. You mean we use technology to make life better? So there's no such thing as cheating. Everything we are doing right now, including broadcasting this live so people don't have to fly here and drive here to hear us. Right. Is cheating. Exactly. So stop it. We're talking about effectiveness. We're talking about efficiency. We're talking about quality of life. And if you want to put shame and guilt on that, get a therapist. It's not okay. I just don't need anybody ever telling me what is what and what is not what like that when I'm trying to take care of myself. Yeah. I don't need that. Yeah, absolutely. And just straight up. yeah guys I'm cheating I'm cheating every which way I can right I do everything to make my body healthier my mind healthier I use neurofeedback instead of meditating because it's more effective per minute I use breath work instead of meditating or with meditation because it works better yeah right and I use performance enhancers because I like to perform well that's right it's okay and I use ones that I don't use Adderall this is terrible for you yeah I don't use cannabis I drink like once or twice a year if it's older than me because it's not good for you right but there is, I'm on modafinil right now. I've been on modafinil for 25 years, every day, almost every day anyway, about a hundred milligrams, sometimes 50. Yeah. And you know what? It is one of the most effective and studied pharmaceuticals for cognitive function. And I have no problems talking about it. And if you think I'm cheating, that's because you're losing. Maybe you've tried modafinil. Well, and just because some doctor tells you that this is what you're supposed to take. If you look into it and you find yourself getting worse off when you're taking it and you got to take more to compensate for that, to compensate for that, to compensate for that. I ask you, does that sound correct? How does that sound right that you have to take this to offset this to offset this to offset this? Next thing you know, you're on 35 different medications. I know how to fix that. Let's mandate that people be forced to use medications so they don't have any choice at all. That's a good idea, isn't it? Yeah. Oh, yeah. Now, I spit in the face of that, literally. Yeah. I mean, that's why we do what we do. It's exactly why we do what we do. And I will not ask for a permission slip. No. to take care of myself. Me either. It's a fundamental, innate right. And it's funny, Benjamin Rush, one of the founding fathers on the Constitution, he was like, guys, if we do not put something in the Constitution about the right to medical autonomy, that we will have medical tyranny in the country. And that happened. And there's even a Broadway play about it. But man, we could just do that right now. And I almost feel like there might be enough after all this COVID nonsense, there might be enough press. There'll be some people still wearing masks with blue hair who are angry about that, but they're going to be angry anyway. Who cares? I was on the plane and this lady was sitting next to me with her mask on and then takes it off to start eating. And all I could think about was, you know, COVID just stopped working and it stopped moving around when you decided to eat. You know, you could sit down and you could eat. Now it was all good, but as soon as you put that mask back on, you were safe again. It was probably a bag of chips, right? Oh, that was the thing. I actually, I was, I had the internet hooked up and I was texting my wife and I said, this woman is eating dog shit next to me and thinking she's protecting herself. She's feeding herself all of this toxic crap that they hand out to you and then breathing in all the air that everybody else is when she takes it off to do it. I can't believe, and I could never wrap my head around how many people just fell in line with that and acted like that was sensical. Like that was okay. I just am lost and then when like when when the curfews would come in because covid just uh you know it it only goes at nine o'clock at night or whatever they were doing it you know i i just i can't wrap my head around any of that and in fact she admitted he made up the six foot thing yeah and i still see signs about that somewhere i take them down when i see him but i'm like he admitted that and he's not in jail what happened to that guy i am so lost yeah i am so lost i i like i can't wrap my head around a half of it. The bottom line is, if you want to live a long time, you want to feel really good, you're not the most profitable consumer. So you got to do that work for yourself. And there are plenty of physicians, a lot of functional medicine. That's right. They're down to help. And there's guys like you and me. And we'll share what we know. We're not doctors. You don't need to be a doctor to manage your own health. The vast majority of this is lifestyle. There's some tech you can use. you got your Apollo Neuro on mine's charging right now sorry Dave and that's just that's how it is and yeah there might be some pharmaceuticals there might be some whatevers but nobody gets to tell you that's the most important thing I agree 100% and that's why we do what we do and I always tell people if you disagree go do all of the shit that you want to do take all the vaccines take whatever you want but don't mind me because when I'm healthy and I'm living happy. I'm going to tell you what I do and you can take it for what it's worth one way or another. And that's it. And the reality is if you can tell me what I have to do, then I can tell you what you have to do and you can pound sand with your face. So let's not go there, right? Because the sand is going to hurt and I'm not going to eat kibble. It's just not going to happen. No, no, no, no. And it's a, it is so nice to know, like when I found you that people like you were there that I could look at and go, okay, they got it. And I know I'm not nuts by any stretch of the imagination we just needed a name for what we do so we could have community that's it that's why the that's why i do the biohacking conference in our 13th year now 5 000 people beyond biohacking.com i'll see you there for sure favorite event of the year man it is so good now we i did a mini documentary of going through there last year i have online it was the it's such a phenomenal time and you know what i love about it is there's so many people in there even with differing opinions that are there for the same reason yeah to fix ourselves and help others do this yeah like you can be carnivore I don't think it's gonna work long term no you can be vegan and come and it we might not have food for you but that's your problem you're not eating food anyway but you know that that's just how it's like everyone's welcome and and you don't have to agree and that is one of the spaces where I don't care about your politics I don't care about your your nutritional stuff as long as it's working for you and then we can be curious about each other and I just like to learn from people even with the most complex or differing opinion because then I either learn something to try or I say, man, I know what not to do, but you're still learning something, you know, and it's, it's a beautiful thing and what you do and the things that you've done over all the years. And, you know, people take their opinions however they want, but I can tell you this for me and from people like me that came in, it's beyond appreciative and you help shape a lot of the things that I do. Oh man. Thank you. Yeah. And it's, it's something that I always come back to. and then I take what you've done, try to mix it with what I've done, come up with the greatest things possible. You've done massive and you still do. And it's for me coming from where I came from, it really helped me to grow in a variety of ways. That's what I'm here to do. And it's a movement and we're all evolving it together. And I'm grateful to be able to lead it, but I don't own the word biohacking. I didn't trademark it on purpose because that was for all of us. we needed a name for for what we do and now we have a tribe well just know just from somebody like me the the amount of effect it doesn't end you know it only gets bigger and it's helped me to get my knowledge base bigger to help my audience and to keep sharing it and that's that's what it's all about i appreciate it thank you so much thanks for going on the show absolutely and they can find you on instagram at dylan gemelli is it gemelli gemelli yeah dylan gemelli biohacking is the name of your Instagram. So guys, make sure you give them a follow. Appreciate it. I appreciate it. Thanks, brother. See you next time on the Human Upgrade Podcast. The Human Upgrade, formerly Bulletproof Radio, was created and is hosted by Dave Asprey. The information contained in this podcast is provided for informational purposes only and is not intended for the purposes of diagnosing, treating, curing, or preventing any disease. 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