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Dave Asprey

Mentioned in 39 analyzed podcast episodes across 10 shows

A biohacking pioneer and entrepreneur best known for founding the Bulletproof brand and coining the term "biohacking," he hosts The Human Upgrade podcast where he discusses longevity protocols, supplement optimization, and biological performance enhancement. He is frequently referenced across wellness and health podcasts for his extensive personal experimentation with supplements, peptides, and optimization techniques, as well as his promotion of ambitious longevity goals. He has also appeared as a panelist on technology-focused podcasts discussing AI and institutional governance.

Episode Appearances

Moonshots with Peter Diamandis

Moonshots with Peter Diamandis · Apr 11, 2026

SpaceX Goes Public, Claude’s Mythos Release, and the US Data Center Delay | EP #246

Co-host discussing SpaceX valuation, AI adoption, and one-person unicorn business models

SpaceX IPO and Starlink profitability modelAnthropic Mythos model capabilities and safety withholdingOpenAI competitive pressure and Spud release timing
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Culture Apothecary with Alex Clark

Culture Apothecary with Alex Clark · Apr 10, 2026

The Biohacker’s Guide To Sleep, Nicotine, & Weight Loss | Dave Asprey

Guest discussing biohacking movement, weight loss, longevity optimization, and health transformation strategies

Bulletproof Coffee and MCT Oil Weight Loss MechanismOxalate Toxicity and Plant-Based Diet RisksCircadian Rhythm Optimization Through Light Control
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Mind Pump: Raw Fitness Truth

Mind Pump: Raw Fitness Truth · Apr 10, 2026

2833: Why Fitness Gimmicks Keep Fooling You And What Actually Works

Mentioned as proponent of one-rep max machine technology claiming intensity-based training benefits

Fitness Gimmicks and Equipment EfficacyEMS (Electrical Muscle Stimulation) TechnologyMuscle Fiber Recruitment vs Force Generation
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Biohack-it

Biohack-it · Apr 2, 2026

Your Laundry Detergent Might Be the Most Toxic Thing in Your Life — Branch Basics Explains Why

Referenced by host as influential figure in functional medicine and biohacking movement that inspired her health journey

Endocrine-disrupting chemicals in household productsFragrance labeling and proprietary ingredient disclosure gapsPCOS and endometriosis reversal through environmental toxin reduction
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Passion Struck with John R. Miles

Passion Struck with John R. Miles · Mar 24, 2026

Why Humans Are Wired for Love but Struggling to Connect | Dr. Justin Garcia — EP 745

Earlier guest in 'Life Beyond the Script' series discussing biology and resilience

Evolutionary biology of pair bonding and romantic loveNeurobiological mechanisms of romantic attachment and rejectionTouch deprivation and physical intimacy in modern relationships
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Biohack-it

Biohack-it · Mar 19, 2026

Frequency Medicine: How to "Reset" Your Body Without Pills or Supplements

Biohacking influencer who appeared on host's vision board and became client and friend through manifestation alignment

Frequency Medicine and Sympathetic ResonanceNervous System Regulation and Vagal ToneSleep Optimization and REM Sleep Enhancement
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Passion Struck with John R. Miles

Passion Struck with John R. Miles · Mar 12, 2026

Become the CEO of Your Health Through Resilience | Dr. Tara Narula — EP 740

Guest in previous Passion Struck episode discussing biological resilience and nervous system

Resilience as a learnable skill for health outcomesMind-body connection and stress physiologyPatient advocacy and becoming CEO of your health
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Passion Struck with John R. Miles

Passion Struck with John R. Miles · Mar 10, 2026

How to Biohack the Brain to Remove Emotional Triggers | Dave Asprey - EP 739

Founder of biohacking movement; entrepreneur and author discussing emotional triggers, neurofeedback, and biological optimization

Neurofeedback and brain-state optimizationCore childhood traumas and emotional triggersMitochondrial function and cellular energy
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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+ · Mar 9, 2026

BONUS: "The Sympathetic Spiral of Doom!” – The Fastest Way To Reset Your Nervous System & End Burnout with Dr. Scott Sherr | Menopause, Perimenopause & Mental Health

Biohacker mentioned as using nicotine spray for cognitive enhancement and focus during podcast recording sessions

Sympathetic Nervous System Dysregulation and Chronic StressMitochondrial Dysfunction and Energy ProductionPerimenopause and Menopause Hormone Optimization
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Passion Struck with John R. Miles

Passion Struck with John R. Miles · Mar 6, 2026

Is Your Success Hollow? When the Script Stops Making Sense | John R. Miles EP 738

Biohacking pioneer featured in upcoming episode; discussed overcoming health challenges and rebuilding emotional resilience.

Authentic Leadership and Professional IdentityHollow Success and Achievement Without AlignmentSelf-Editing and Undersharing in Relationships
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Moonshots with Peter Diamandis

Moonshots with Peter Diamandis · Feb 25, 2026

Can AI Replace Teachers? Inside the $40M Company Using AI Tutors to Teach 200% Faster | #233

Co-host (referenced as 'DB2'); asks questions about school environment design and specialist roles

Personalized AI tutoring and adaptive learning systemsMastery-based vs. time-based education modelsLearning science and cognitive load theory in practice
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Moonshots with Peter Diamandis

Moonshots with Peter Diamandis · Feb 19, 2026

Ben Horowitz: xAI Executive Exodus, Apple's AI Crisis, The Pace of AI | #232

Podcast panelist discussing AI adoption in corporations and near-term job displacement patterns

Recursive Self-Improvement (RSI) and AI Singularity TimelineXAI Executive Departures and ITAR RegulationsByteDance C-Dance 2.0 Video Generation Technology
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Moonshots with Peter Diamandis

Moonshots with Peter Diamandis · Feb 13, 2026

The AI CEO Arrives: Sam Altman's Succession Plan, Job Loss Continues, and Our 2027 'Solve Everything' Paper | EP #230

Co-host at MIT; discussing CEO role transformation and institutional governance challenges

AI CEO Succession PlanningJob Loss and Labor Market DisruptionRecursive Self-Improvement in AI Models
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The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance · Feb 12, 2026

Turn Off Your WiFi Tonight and See What Happens to Your Sleep : 1414

Host of The Human Upgrade podcast; biohacking pioneer who coined the term and discusses personal experiences with red light therapy and EMF exposure

Blue Light Exposure and Circadian Rhythm DisruptionEMF Mitigation Strategies and ProductsRed Light Therapy Wavelengths and Applications
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The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance · Feb 10, 2026

The Secret Peptides and Underground Compounds Doctors Won’t Talk About : 1413

Host; biohacking pioneer, discusses longevity protocols, testosterone optimization, and medical autonomy

SARMs (Selective Androgen Receptor Modulators) - LGD-4033, S4, MK677, S23Peptides for longevity - ipamorelin, CJC-1295, sermorelin, melanotan, PT-141, motziapide, semorelinTestosterone replacement therapy - physiological dosing, oral vs. injectable, Kysetrex
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The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance · Feb 8, 2026

Why Your Muscles Break Down After 40 (Do This To Reverse It) : 1412

Host and primary speaker discussing mitophagy, urolithin A, and longevity protocols; takes double dose of Mitopure

Mitophagy and mitochondrial renewalUrolithin A supplementation and bioavailabilityAge-related muscle decline and sarcopenia
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The Dylan Gemelli Podcast

The Dylan Gemelli Podcast · Feb 7, 2026

Episode #89 Featuring Liver and Health Expert, SIGGI CLAVIEN!! The LIVER Episode! An encyclopedia and masterclass on EVERYTHING you need to know about your liver!

Biohacking pioneer; met with Clavien to discuss coffee's liver health benefits; revolutionized coffee industry

Fatty Liver Disease Epidemiology and PreventionFibroScan Technology and Liver DiagnosticsAcetaminophen (Tylenol) Hepatotoxicity and Liver Damage
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Biohack-it

Biohack-it · Feb 5, 2026

Stop Taking Peptides Until You Watch This. (Dr. Ivan Rusilko)

Biohacking pioneer whose books inspired the podcast host's entry into the wellness space

Peptide therapy protocols and medical-grade vs research-grade sourcingChronic viral infections (EBV, CMV) and immune system dysfunctionSleep optimization through peptide combinations (CJC-1295, Ipamorelin, Sermorelin, Cialis, Oxytocin)
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The Genius Life

The Genius Life · Feb 2, 2026

547: How to Take Control of Your Health With Low-Cost Tools and Testing | Darshan Shah, MD

Biohacking pioneer referenced for extensive supplement protocols

Bioimpedance scales for body composition trackingGrip dynamometer testing for longevity predictionContinuous glucose monitoring for metabolic health
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The Dr. Tyna Show

The Dr. Tyna Show · Jan 22, 2026

Stop Taking Supplements Blindly: The Cell Signaling Truth | Dr. Tyler Panzner

Biohacker referenced for taking excessive supplement stacks without understanding pharmacological interactions and contraindications

Cell signaling pathways and disease mechanismsVitamin D genetics and personalized dosing protocolsHistamine intolerance and dietary management
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Jan 22, 2026

When Human Biology Evolves Slower Than the World with James Schmachtenberger

Biohacking pioneer mentioned as example of high-volume supplement user and podcast host

Complex Systems Science Applied to Human BiologyGut-Brain Axis and Neurotransmitter ProductionReductionist vs. Systems-Based Medical Models
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Biohack-it

Biohack-it · Jan 22, 2026

She’s 70 with the Brain of a 30-Year-Old: The Algae Secret

Biohacking conference host; Arnston has appeared at his events 5-6 times over years

Mitochondrial Function and ATP ProductionSuperoxide Dismutase (SOD) and Antioxidant ProtectionAlkaline Diet and pH-Based Disease Prevention
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The Dylan Gemelli Podcast

The Dylan Gemelli Podcast · Jan 17, 2026

Episode #82 Featuring Sean Fetcho! The co-founder of Versea Health and MESCREEN! The World's FIRST AND ONLY at home Mitochondrial Efficiency Test!!

Biohacking pioneer; mentioned for promoting longevity goal of reaching age 140 without quality-of-life focus

Mitochondrial Efficiency Testing (MESCREEN)Preventative vs. Reactive MedicineBiohacking Industry Bubble and Market Consolidation
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Biohack-it

Biohack-it · Jan 8, 2026

The Weight Loss Lie Dave Asprey Says Is Keeping You Stuck

Biohacking pioneer and author discussing personal health transformation, consciousness work, and longevity optimization techniques

Mitochondrial dysfunction and energy production as root cause of weight gain and metabolic diseaseSupplement stacking and personalized micronutrient protocols for longevityGene therapy for longevity (senolytics, VEGF, Clotho)
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The Dylan Gemelli Podcast

The Dylan Gemelli Podcast · Jan 5, 2026

Episode #77 Featuring Dr. Rewire! How to "Rewire" Your Brain! Connecting the mind and body, Neuro flexibility, The role of neurotransmitters, Balancing the brain, Effects of stress and more!

Biohacking conference host where Dr. Rewire spoke about epigenetics and DNA optimization

Brain DNA Testing and Neurotransmitter ProfilingSympathetic vs Parasympathetic Nervous System BalanceNeuroflexibility and Nervous System Adaptation
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The Dylan Gemelli Podcast

The Dylan Gemelli Podcast · Nov 25, 2025

Episode #69 Featuring Dr. Vincent Pedre! Happy Gut Coffee, Mitochondria, Gut Health, Vagus Nerve, Mind-Body Connection, The importance of breath work, Cellular Membrane Importance and more!

Biohacker and coffee entrepreneur whose Bulletproof Coffee is mentioned as second-tier compared to Happy Gut Coffee

Mitochondrial Health and Cellular VoltageGut Microbiome and Intestinal Barrier FunctionVagus Nerve Activation and Parasympathetic Nervous System
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Nov 6, 2025

Prison, Peptides, and the Myth of Living Forever | Bizzie Gold x Dylan Gemelli

Biohacking entrepreneur promoting 'live beyond 180' longevity narrative; referenced as example of mainstream anti-aging messaging

Peptide therapy mechanisms and applications (growth hormone releasing peptides, GHRP, GHRH, MOT-C, BPC-157, TB-500, GHKCU, KPV)GLP-1 medications (Tirzepatide, Ozempic, Manjaro, Mounjaro) and micro-dosing protocolsUnderground peptide market sourcing, manufacturing, and quality control
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The Dylan Gemelli Podcast

The Dylan Gemelli Podcast · Oct 29, 2025

Episode #62 Featuring Baran Dilaver, Founder of WONDERFEEL! A MASTERCLASS on NAD and NMN! The role of NAD in overall health, The difference between NMN and NAD, The TRUE way to boost NAD and more!

Invited WONDERFEEL to speak at biohacking convention; interested in ergothioneine as standalone supplement

NAD (Nicotinamide Adenine Dinucleotide) biology and cellular energy productionNMN vs NR precursor comparison and bioavailabilityCD38 enzyme and its role in NAD depletion with aging
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Sep 25, 2025

Being Sane in Insane Places: Diagnosis is Broken & Data is the Answer

Podcast host whose audience demonstrated notably high self-awareness in Break Method diagnostic evaluations compared to other audiences

Rosenhan Experiment and psychiatric diagnostic validityDSM (Diagnostic and Statistical Manual) limitations and evolutionChemical imbalance theory debunking
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The Mello Millionaire with Tommy Mello

The Mello Millionaire with Tommy Mello · Sep 5, 2025

Health Is Wealth: Dave Asprey’s Blueprint for Longevity and High Performance

Guest discussing his 25-year longevity journey, $2.5M self-optimization investment, and creation of $36B biohacking industry

Biohacking and human optimizationLongevity science and anti-aging technologyGene therapy and stem cell treatments
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Aug 28, 2025

Faith Over Fear: When Your Health Habits Are Actually Making You Sick

Biohacking conference organizer where host presented on wellness obsession paradox

Nervous System Regulation and Parasympathetic ActivationFear-Based Health Obsession and Orthorexia SpectrumBrain Pattern Mapping and Neurological Predisposition Types
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Aug 21, 2025

MCAS Explained: How Histamine Hijacks Your Brain and Mood

Biohacking conference organizer; mentioned as trusted figure in health optimization space; host encountered HealingSana at his conference

Mast Cell Activation Syndrome (MCAS) pathophysiology and diagnostic criteriaHistamine biochemistry and receptor signaling (H1, H2, H3, H4)Low-histamine diet protocols and food triggers
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Biohack-it

Biohack-it · Aug 14, 2025

Muscle Growth, Gut Health, and Skin Rejuvenation: What You Need to Know About Peptides

Biohacking pioneer; Natalie completed his coaching certification program early in her career

Growth hormone secretagogues (CJC-1295, Ipamorelin, Tesamorelin) for muscle and fat lossBPC-157 and Thymosin Beta-4 for tissue healing and recoveryGHKCU peptide for skin rejuvenation and epigenetic gene expression
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Jul 31, 2025

The Peptide Protocol That Reversed My Autoimmune Symptoms

Biohacking conference host where host spoke on longevity and met Healing Sauna founders

Peptide Microdosing Protocols for Autoimmune DiseaseTerzapatide (GLP-1/GIP Receptor Agonist) Mechanisms and Clinical EffectsBPC-157 (Body Protecting Compound) for Gut Barrier Repair
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Jul 24, 2025

Emotional Eating: Food Isn’t the Problem - Your Brain Is.

Biohacking conference organizer where host discovered Healing Sauna sponsor

Emotional Eating and Brain PatternsSelf-Regulation vs. Co-RegulationChildhood Programming and Food Relationships
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Jul 17, 2025

The Overwhelm Trap: This is Why You Justify Self-Sabotage

Referenced as trusted figure in biohacking community; host of biohacking conference where Healing Sauna was discovered.

Emotional addiction cycles and three-part emotional patternsNeurocognitive funnel and perception-to-behavior feedback loopsEmotional literacy and precision language in self-description
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Jul 7, 2025

It Ends with Us DECODED: Lily, Ryle & Atlas Aren’t Who You Think

Referenced as trusted user of HealingSana sauna product; mentioned in sponsor context

Behavioral psychology and brain pattern mappingIntimate relationship dynamics and trauma bondingConflict avoidance and dishonesty in relationships
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Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation

Decoded | Unlock The Secrets of Human Behavior, Emotion and Motivation · Jun 30, 2025

Beige Flags: Are You Addicted to Chaos?

Referenced as trusted user of HealingSana infrared sauna; host discovered product at his biohacking conference

Beige flags in dating and relationshipsBrain pattern types and underlying motivationsSymbiotic dysfunction and toxic relationship cycles
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Maintenance Phase

Maintenance Phase · Mar 26, 2025

The Bulletproof Diet

Creator of Bulletproof Coffee and Bulletproof Diet; self-described biohacker who spent $1M+ on personal optimization and built multi-million dollar product business

Bulletproof Coffee and MCT Oil Marketing ClaimsKetogenic Diet and Intermittent Fasting EfficacyCherry-Picked Scientific Research in Wellness
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