Is Toothpaste Hurting Your Child’s Brain? | Dr. Nathan Bryan | DSH #1840

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And then how we've been able to take the science of nitric oxide and translate that in the clinical medicine product technology that actually restores the body's ability to make it. And when I think of nitric oxide, I literally picture your face now. Oh gee. That's how like. Well my PR and media and agency are doing a good job then. That's how I feel like you've positioned yourself when people think of nitric oxide though. Well look, I spent 25 years in academia. I mean I spent my entire adult career studying this single molecule. And you know I've always believed that to be successful, do one thing and do it better than anybody else in the world. So that's what we've done. Any new studies or things since the last time you came on in regards to nitric oxide? Well we're moving the field forward. We've got drugs now for heart disease that we're developing through the FDA. We've got a drug for Alzheimer's which I'm convinced will completely eradicate Alzheimer's on nitric oxide drug therapy. Wow. Because Alzheimer's is a vascular metabolic disease that leads to protein misfolding. So it's hypoprofusion of the brain. It's insulin resistance in the brain which we call diabetes type 3. And what does nitric oxide do? It dilates the blood vessels, it improves glucose uptake, it improves mitochondrial function. When you get the cells of the brain, the oxygen, the nutrients, and activate their mitochondria, then you don't get misfolding of proteins and you don't lose cognition. That's very true. That's what nitric oxide does. Because they say Alzheimer's starts when you're very young, right? Like you start building it up in your 20s and your 30s. Well I mean there's risk factors. So everything that we know, risk factors that are associated or lead to a loss of nitric oxide production, increase your risk for developing dementia and Alzheimer's. So what is that? High blood pressure, erectile dysfunction, smoking, poor diet, sedentary lifestyle, all those decrease nitric oxide production. The end result is lack of blood flow, insulin resistance, and then eventually Alzheimer's. Yeah. You're seeing a lot of Alzheimer's and a lot of erectile dysfunction too these days. So erectile dysfunction precedes dementia and Alzheimer's. Oh it does. So it's like a... Yeah, it's what we call the canary in the coal mine because think about it. Erectile dysfunction is the lack of the ability to dilate the blood vessels of the sex organs. So when we need to recall memory or have some executive function, we've got to dilate, we've got to profuse certain regions of the brain. So if you can't dilate the blood vessels of the sex organs when you're going to have sex, then you can't, that same dysfunction occurs in the brain, in the cerebral organs. So now you've lost the ability to dilate blood vessels, increase blood flow on demand. And that's what nitric oxide does. So ED is a risk factor for one of heart disease, Alzheimer's, diabetes. And it's all related to lack of nitric oxide. Yeah, that makes a lot of sense. So it's like a precursor. For sure. And there's guys in their 20s with it now. No, look, and here's the therapeutic solution is this drugs like Viagra and Cialis, the PD-5 and Hidr's. But we know that those drugs only work in 50% of the men in which they're prescribed. So 50% of the people that have ED, men who have ED, don't even get a therapeutic benefit from drugs like Viagra. And what we've discovered is that... Hiya, I'm Elena, just your average walking, talking, dancing, singing puppet. A puppet that loves an LNER train journey. It beats the CER every time. I'm free to do all the things I love, get lost in a true crime series, type away like an office ninja, order yummy food and drinks to my seat, or just have a cheaty power nap. And now, with more services and faster journey times, there's more freedom all the way with LNER. Selected routes only. Visit lner.co.uk slash timetable for details. We talk a lot on this show about taking risks and trying to get ahead. But let's be real, the world feels shaking right now. AI is changing jobs, markets are all over the place, nothing feels guaranteed, and at some point you realize no one's coming to save you. You've got to protect yourself, and one thing people forget about is life insurance. If you're new to it, you're not alone. That's why I checked out Select Quote. They've been around for over 40 years and helped more than 2 million Americans buy coverage that actually fits their life and budget. They compare policies from top-rated insurance companies and do their work for you for free. You can even get same-day coverage up to $2 million with no medical exam. Life insurance is never cheaper than it is today. Get the right life insurance for you, for less, and save more than 50% at selectquote.com slash dsh. Save more than 50% on term life insurance at selectquote.com slash dsh today to get started at selectquote.com slash dsh. Drugs like vagra are dependent upon the body's ability to make nitric oxide. So in these people who don't respond to vagra, their body doesn't make any nitric oxide to activate that second messenger system that vagra can enhance or potentiate. So that told us 20 years ago, erectile dysfunction is a symptom of nitric oxide deficiency. And we have to treat it as such. I don't personally ever want to take my agrar. Did you see Demo Zarin talk about his experience with it? No, I missed that. Oh, you missed that? But look, the goal of medicine should be to never prescribe drugs. Understand the root cause of disease and implement what we call restorative physiology. Give the body what it needs, remove the body from it, what it doesn't need. And then the body heals itself. And in that paradigm, there is no need for drug therapy. And that should be our goal. That should be the goal. Yeah. But instead we got average elderly person on what, over 10 medications. Yeah, at least. I mean, we did a COVID drug study during COVID from 2020 to 2023. And some of these patients that we enrolled in our clinical trial were on 24 different medications. Oh my God. 50 to 80 year old people on 15, 20, 20, 42. I mean, and they wonder why they're sick. When your body's exposed to 24, 25 different synthetic compounds that inhibit normal biochemical reactions, the body can't perform. Because there's a side effect for each one they take, right? That's right. So then they got to take another one. It's a vicious cycle. Crazy. 24 is insane though. Yeah. Why would you wake up and rely on 24? These people were zombie like and they wonder why they're, it's susceptible to viral disease and all these other comorbidities. I mean, we got to do better. We understand the mechanisms of these to the extent that we can eliminate drug therapy and fix it, address root cause. You know, that's one of the benefits of the A4M because we're addressing root cause and really getting to longevity medicine. Yeah. Part of me feels for them because I feel like that generation really trusts doctors. Like they really value their opinions, you know, and they'll just, as soon as they say like, you need to take this, they're like, yeah, let's start taking that. Well, now that's been the problem. We've been conditioned to trust doctors, never question doctors. And we have to question everything now. I mean, the goal of medicine should be to understand what's causing the symptoms, not treat the symptoms with drug therapy, but then correct, take corrective measures because we know diet and lifestyle is key. Yeah. But, you know, we've been conditioned to, you know, just take a pill. You don't have to change your diet. You don't change your lifestyle. We're just going to give you this pill. And that's easy. But health is not easy. I think it's simple, but it's not easy. Respect for saying that first of all, because you are literally a doctor. And we have to do better. I taught in medical school for 15 years, teaching future physicians. And, you know, we understand the biochemistry and the physiology to the extent that we have to address what's causing people to get sick. And all you have to do is look at the numbers. We have the most advanced civilization in the history of the world. And yet we have the sickest people on the planet. Americans are the sickest people. And why is that? It's because most people get sick, get symptoms and we take drugs, but we never address the root cause of why we get sick or don't optimize our human physiology. A valid point, because I think during the pandemic, didn't we lose either the most or the second most out of any country? You know, I don't even know what numbers to believe. Yeah. I don't believe anything that happened during COVID. You know, the so-called experts, you know, I think we were duped. Because they were labeling a lot of deaths as COVID. So it's hard to know. Yeah. Seasonal flu. During those three years of COVID, there was not a single death due to influenza. And every year we know 20 to 60,000 people die of influenza. But the same people who got sick and died from COVID were the same people that got sick and died from flu for the past 100 years. There's known risk factors. And what we found is that the people who are nitric oxide deficient, whether people get sick and die from flu, people got sick and died from COVID. So let's address restoring nitric oxide production, mitigate those risk factors, and make you resistant to viral infections. I've never had COVID. Wow. I had it before at times. I didn't get the shot. I didn't wear a mask. I was exposed to COVID and I've never had COVID. Were you on, can I ask if you are on nicotine? Hiya, I'm Elena, just your average walking, talking, dancing, singing puppet. A puppet that loves an LNER train journey. It beats the CER every time. I'm free to do all the things I love, get lost in a true crime series, type away like an office ninja, order yummy food and drinks to my seat, or just have a cheeky power nap. And now, with more services and faster journey times, there's more freedom all the way with LNER. Selected routes only. Visit LNER.co.uk slash timetable for details. We talk a lot on this show about taking risks and trying to get ahead. Let's be real, the world feels shaking right now. AI is changing jobs, markets are all over the place, nothing feels guaranteed, and at some point you realize no one's coming to save you. You've got to protect yourself and one thing people forget about is life insurance. If you're new to it, you're not alone. That's why I checked out Selected Quote. They've been around for over 40 years and helped more than 2 million Americans find coverage that actually fits their life and budget. They compare policies from top-rated insurance companies and do the work for you for free. You can even get same-day coverage up to $2 million with no medical exam. Life insurance is never cheaper than it is today. Get the right life insurance for you for less and save more than 50% at selectquote.com slash dsh. Save more than 50% on term life insurance at selectquote.com slash dsh today to get started at selectquote.com slash dsh. I never took nicotine. Okay, because I know there was some studies on people that were taking nicotine were a little more immune. Well, I think for us what we recognize is that the spike protein binds to the ACE2 receptor. And so in people who are nitric oxide deficient, there's an up-regulation of the ACE2 receptor. So there's more binding sites for the spike protein. People who take nitric oxide like me or who are nitric oxide replete, the ACE2 receptor is down-regulated. So we may be exposed to COVID or the spike protein, but there's no receptor for it to bind to. So we become resistant to viral infections. Wow, just by having proper nitric oxide. That's right. And understanding the signaling aspects and down-regulation of adhesion molecules, decreasing inflammation, oxidative stress, and immune dysfunction, and allowing the immune system to go. Because we've known since 2005 that nitric oxide prevents coronavirus replication. That was SARS-CoV-1. SARS-CoV-2 or COVID-19 is basically the same mechanism. So it prevents viral replication. And it's how our innate immune system works, similar to bacterial infections. If we get a bacterial infection, our immune system is mobilizing. We generate nitric oxide. It binds to the orange sulfur centers of the bacteria. Shuts down the respiration and kills it. But if you can't make nitric oxide, if you don't have a good immune system or a good cardiovascular system, the bacteria or the viruses become immune to the cardiovascular system because poorly vascularized tissues are more prone to infections. So for me, it's been all about blood flow and circulation. And that's what happened in the pandemic. Everyone's immune system was weakened, staying inside all the... And everything that the so-called experts were recommending made us more susceptible. Social isolation, wearing masks, re-breathing carbon dioxide, using antiseptic, you know, antibacterial wipes, sterilizing our environment. Can't focus, struggling to sleep, or feeling wired? This balances your brain and body fast. A cutting-edge EEG study found something phenomenal with quantum upgrade. Stress-related brainwave activity dropped by 80%. Calming alpha waves in the limbic system increased over 13x and HRV improved big time. That's just the start. 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That's always, you know, for 30-something years, I've published over 100 peer-reviewed papers, and we made this observation that there's oral bacteria that are responsible for the production of nitric oxide that are regulating blood pressure. So anything that kills oral bacteria will decrease nitric oxide production and cause an increase in blood pressure. But that's the headline grabber. Watch this causes high blood pressure. Yeah, because it's something that just everyone did grown up. No one questioned it, no one questioned brushing with fluoride grown up, or using mouthwash. I know, but you get, look, I always look back and say, why were we doing this? Why was this ever introduced? And I think it was with good reason, because 100 years ago was first this oral systemic link. People with bleeding gums, poor oral hygiene, had higher heart attacks and strokes. Incidents of heart attack and stroke. So the solution back then, well, let's kill all the bacteria. Let's use chlorhexidine, let's use fluoride, and let's sterilize the oral environment. But now fast forward 100 years, we know that there's a microbiome. There's bacteria that live in the mouth, on the skin, in the gut, and if we kill these good bacteria, it causes systemic disease. So we know better, and we got to do better. So we have to support the microbiome today. We know that. We can't destroy it. But yet, two out of three Americans still use mouthwash. Probably 99 out of 100 people are using fluoride in their toothpaste, and it's causing complete dysbiosis. Fluorides in neurotoxin decreases IQ in kids by as much as seven points. There's no benefits, it's all risk, so get rid of it. We have to get rid of it. That's terrible, seven points. Yeah, no, that study was published last year in September. Dude, that could ruin your life in certain situations. Yeah, that was it. That's a lot of intelligence gone down the drain. Yeah, in kids, early on. Yeah, that's terrible. I don't think you recover from that. It's really hard, they say, to gain IQ back, or gain IQ at all. Jesus, seven points, it's terrible. But even if they remove it from the tap water, it'll still be everywhere, right? I don't think so. When you look at risk benefit, because everything we do in terms of medicine, public policy, what is the benefit this can provide? And at what risk? And now the data are very clear, there's no benefit to fluoride. It doesn't improve teeth mineralization. It doesn't prevent cavities. Hiya, I'm Elena, just your average walking, talking, dancing, singing puppet. A puppet that loves an LNER train journey. It beats the CER every time. I'm free to do all the things I love. Get lost in a true crime series. Type away like an office ninja. Or order yummy food and drinks to my seat. Or just have a cheaty power nap. And now with more services and faster journey times, there's more freedom all the way with LNER. Selected routes only. Visit lner.co.uk slash timetable for details. We talk a lot on this show about taking risks and trying to get ahead. But let's be real, the world feels shaking right now. AI is changing jobs, markets are all over the place, nothing feels guaranteed. And at some point you realize no one's coming to save you. You've got to protect yourself and one thing people forget about is life insurance. If you're new to it, you're not alone. That's why I checked out Select Quote. They've been around for over 40 years and helped more than 2 million Americans find coverage that actually fits their life and budget. They compare policies from top-rated insurance companies and do the work for you for free. You can even get same-day coverage up to $2 million with no medical exam. Life insurance is never cheaper than it is today. Get the right life insurance for you for less and save more than 50% at selectquote.com slash dsh. Save more than 50% on term life insurance at selectquote.com slash dsh today to get started at selectquote.com slash dsh. Okay, so if there's no benefit and there's risk, what's the risk? It's a neurotoxin. It shuts down your thyroid function. It's antiseptic and it lowers IQ. So eliminate it from any source of exposure. Dennis got to get rid of it in their practices. The municipalities, 73% of municipalities in the U.S. have fluoride in their drinking water. You must remove it and get rid of fluoride and toothpaste. And then people will get better. We got uranium in our top water here. Urine? Okay. No, look, I think that's why it's so important for people to have home filtration systems to filter the water. Because look, it's not just the water we're drinking. It's the water we're bathing in. It's the water we cook in. It's a water that's extremely important. It's everywhere. Yeah, when you shower, you absorb a pint. That's even worse because you're heating it up to a hundred and four hundred and ten degrees. Now you're volatilizing it. The chloride, the fluoride. You're inhaling it, right? Yeah. That's why I don't use steam rooms anymore. I used to love them. It's the water supply. What's the biggest thing to look out for other than fluoride, do you think? I think the big culprit are antacids. Antacids? Antacids, what we call proton pump inhibitors. These are the prescriptions of Romeperzol and Pentopazol. And then the over-the-counter proton pump inhibitors are things like previsin, nexium, prolasec. These drugs are causing a 40% increase in heart attack, stroke, and Alzheimer's. And it's because they're completely inhibiting nitric oxide production. And yet there's 200 million prescriptions written for antacids every year. Two out of three Americans are using these over-the-counter. You don't even have to have a prescription for these drugs. And they're causing death and destruction. Oh my God. That's crazy. 200 million a year you saw? 200 million prescriptions just in the U.S. That's like two-thirds of the population. No, that's right. That's insane. And people have been on these antacids for years, decades. And the data show that if you've been on them for at least three years, 40% greater incidence of heart attack, stroke, and Alzheimer's. And people take these just... A candy, they're a problem. A candy every day. How reversible is that damage if they're on it for years? Well, here's the problem with those drugs is you can't just quit them cold turkey. You have to wean off of them because you're going to get a hypersacretion of stomach acid. It's going to make your life very miserable. So we have to start implementing protocols to slowly wean off because you need stomach acid to break down proteins and terminal acids. You need stomach acid to absorb B vitamins, calcium, zinc, iodine, selenium, chromium. And so you become nutrient deficient if you're on antacids. And then you're inhibiting nitric oxide production. So it's the perfect recipe for chronic disease. If I wanted to completely destroy one's life and physiology, the first thing I'd do to put them on a proton pump and hydrant. Second thing I would do was get their cholesterol below 200 and give them a cholesterol lowering medication. The other thing I would do is put fluoride in the drinking water. And that's our healthcare system. Yeah, the statins are crazy. Statins, yeah. That's the whole debate. It makes you completely dependent upon pharmaceuticals for the rest of your life. And it's a great business model. It's a great financial model, but it's at the expense of our own health. It's a great model because they always talk about the heart and everyone worries about their heart. So as soon as they're like, you got heart issues, take the standard, like, yeah, let me get that, you know. Yeah, but if you look at the data, if someone who knows how to read clinical trial data and look at the absolute risk the number of patients to treat to see an effect versus the relative risk what they report, there's no benefit to cholesterol lowering medication. Either in primary prevention of heart attack, secondary tertiary prevention, there's zero benefit. So again, it goes back to the discussion. If it's no benefit, then we'll go, okay, what's the risk? Right. The risk is muscle cramps and pains, myalgia, diabetes, these statins or mitochondrial toxicants because they're causing certain cancers. So if there's no benefit and it's all risk, that's a very easy quotient. Nope. You don't give it to anybody. The data are very clear. So cholesterol doesn't cause heart disease. Why would you target it if it's not the causal agent? And it doesn't. So that's early on in the 80s, that was the prevailing hypothesis. But again, science prevails, data are the data and it's clearly shown that lowering cholesterol does not prevent heart disease. So why treat it? So many people think the two are linked, cholesterol and heart disease. Yeah, because that's what the American Heart Association and all the American Medical Association and big pharma's ingrained in our mind for the past 30, 40 years. Cheerios. Cheerios. No. I always associate with that. There's a reason. Look, I'm trained as a biochemist and physiologist. There's a reason our body makes cholesterol because we need it. If you can't make cholesterol, you can't make testosterone. Women can't make estrogen. You can't make vitamin D. You become immunocompromised. And we have an epidemic of men with low testosterone, women with hormone disorders, an epidemic of immunocompromised people because they have vitamin D in their 30s, below 50, which makes them immunocompromised. I think my high LDL or LDL cholesterol is out of thing. I think mine was like 111. They said that was high. Yeah, but look, the standard lipid panel looking at cholesterol, LDL and HDL has zero prognostic or diagnostic value. Zero. It's not predictive. It's not diagnostic. What you have to look at are the different kind of advanced lipid panel. What's the amount of oxidation that's occurring to the lipoprotein particles? The particle size, number, intensity. Got it. Yeah, I don't think they measured that. They just give you total cholesterol, LDL, HDL, and then try to treat you to normal. Yeah, they tell you to stop eating eggs. Stop eating eggs, yeah. I don't want, if normal is the general population, I don't want to be normal. I hate how they always compare your blood results to the normal. Hiya, I'm Eleanor, just your average walking, talking, dancing, singing puppet. A puppet that loves an LNER train journey. It beats the CER every time. I'm free to do all the things I love. Get lost in a true crime series. Type away like an office ninja. Order yummy food and drinks to my seat. Or just have a cheeky power nap. And now, with more services and faster journey times, there's more freedom all the way with LNER. Selected routes only. Visit lner.co.uk slash timetable for details. We talk a lot on this show about taking risks and trying to get ahead but let's be real, the world feels shaking right now. AI is changing jobs, markets are all over the place, nothing feels guaranteed and at some point you realize no one's coming to save you. You've got to protect yourself and one thing people forget about is life insurance. If you're new to it, you're not alone. That's why I checked out Select Quote. They've been around for over 40 years and helped more than 2 million Americans find coverage that actually fits their life and budget. They compare policies from top-rated insurance companies and do the work for you for free. You can even get same-day coverage up to $2 million with no medical exam. Life insurance is never cheaper than it is today. Get the right life insurance for you for less and save more than 50% at selectquote.com slash dsh. Save more than 50% on term life insurance at selectquote.com slash dsh today to get started at selectquote.com slash dsh. But what is normal? It's a bell curve. It's 95% confidence intervals within 95% of the population. I don't want to be that. All you got to do is walk around and look, do you want to be like 95% of the people that are walking around? 95% of the people walking around are metabolically unfit. 93% of Americans are metabolically unfit. Two out of three Americans have high blood pressure. Two out of three Americans are obese or overweight. I mean, count me. I don't want to be normal. That's normal. You're out of pre-Europe base. Yeah, I don't want to be normal if that's normal. I want to be optimal. Crazy. I wonder what the healthiest country is. It's got to be like... That data's out there. I don't know what it is. Mediterranean diet somewhere in Europe, I'd imagine. Maybe Japan or Asia. I think Japan, certainly. I mean, they have the highest number of centurions. People live greater than 100. I don't know what their overall health span is. Yeah, country would be tough because there's so many different cities. Yeah, and now the whole world is a melting pot, right? We've got convergence of cultures and different ethnicities. Yeah. Still taking your pre-workout after you get to the gym? You're already late. What if your pre-workout actually worked with your body? Are you tired of artificial energy drinks? BNO beats, a beat-based nitric oxide booster that supports your body's natural nitric oxide production for increased blood flow, mitochondrial ATP energy, and endurance naturally. N101 nitric oxide lozenges is a smarter way to fuel your workout. Just dissolve it in your mouth and it starts working before your first rep. No mixing, no jitters, no crash. More nitric oxide means better blood flow, stronger pumps, and sustained energy without caffeine overload, plus it supports your cardiovascular and cognitive health too. You can support your body's nitric oxide production daily and feel the difference with N101. Just mix one packet with a little water and take it as a shot 10 to 20 minutes before training. Pop a lasage 10 to 15 minutes pre-workout and feel the difference. Train smarter with N101 at N101.com. So when you started speaking out against all this because you said you were teaching for 15 years to lose your job, what happened there? We made over the past 25 years starting to be fundamental truths. These are truths based on normal physiology. And I like this quote by Schopenhauer from 1600s. Truths go through three stages. They're opposed or they're ridiculed, they're violently opposed, and it's accepted as being self-evident. So obviously I was ridiculed early on with my academic colleagues. I left academia because I knew that I didn't want to put my technology in the hands of other companies to see it forward. So I left academia to become an entrepreneur, started companies, and then I productized, commercialized my discoveries. But I kept a, you know, kind of a presence in academia for probably five or six years. But then it's very difficult to do two jobs, be a full-time professor of medicine, be an entrepreneur running companies. So I made a decision to step aside from academia and run these companies. But, you know, as we've progressed the technology, competitors have entered the market and, you know, they've come after me. I've been sued personally. My companies have been sued. For what? For telling the truth and identifying products that don't work. Because when companies that do not understand the science of nitric oxide really have no business commercial or selling a nitric oxide product. Because they don't understand the science. It's not like a vitamin C or vitamin D. We can put in a capsule and give it to you and treat a number. Your vitamin D is 30. We'll give you a vitamin D and get to 80 or optimum. Nitric oxide is a gas. It's going in less than a second when it's produced. So unless you understand how the body makes nitric oxide and what leads to the loss of its production, then these companies out there have no business selling a nitric oxide product. Because it's a complex science. Yeah. So when I started testing products, nitric oxide products and revealing that they didn't work. They didn't like that. They didn't like that. No, because this is a big industry. I can't believe you could sue for that though, because you're literally factually testing it and showing the results. It's not like you're defaming them. No, well, there's look, anybody can sue anybody, right? But there's merit to it or not. So look, we defend, we stand on truth. We defend our science. It's a business strategy. Big companies sue little guys all the time to deplete them of the resources. It's the art of war. And it's a business strategy. We stand on truth and we've survived it and we're moving forward. I love it. Where can people watching this get some product? I think we have a discount code that we set up. Yeah, so the product technology can be found at N101.com. My company is called Brian Therapeutics and we're developing drug therapy, but we have a consumer line of products with an N101 brand. We make a lozenge. We make a fermented eat powder for pre-workout and energy. We make a complete skincare line of products. I developed a nitric oxide-friendly toothpaste, fluoride free, targeting the microbiome, improving the diversity, improving nitric oxide production. Yeah, so N101.com. That's the letter N, number one, letter O, number one. Code DSH, I believe we set up. Yeah, keep on code DSH. Perfect. And then, yeah, I've got a new book I just published in February. We launched it on Fox and Friends in New York. Nice. Brick Tower Press and my agent, Alan Morel, made that happen. But yeah, it tells the story of nitric oxide, kind of my personal journey of discovery. So I think it's a must read. People need to know what nitric oxide is and understand its importance. Beautiful. Check out the books, guys. Check out the products. I use the toothpaste and I love it, so thank you, man. Good seeing you again. Yeah, good seeing you. See you soon. See you guys.