Biohack-it

The Anti-Aging Masterclass: Regenerative Aesthetics, Peptides, Microneedling & More

52 min
Nov 13, 20257 months ago
Listen to Episode
Summary

MJ, a regenerative aesthetics expert and founder of Tonic, discusses alternatives to traditional fillers including stem cells, peptides, microneedling, and Renewva. The episode emphasizes that true anti-aging results come from cellular health optimization, combining internal protocols with external treatments, and proper patient education on ingredients and realistic timelines.

Insights
  • Regenerative aesthetics (stem cells, exosomes, Renewva) require 8-16 weeks to show results versus immediate filler effects, demanding patient education and realistic expectations
  • Hormonal optimization and nutritional supplementation are foundational to aesthetic outcomes; women over 40 often need testosterone and vitamin D rather than SSRIs for mood/energy issues
  • Genetic testing for personalized supplementation based on DNA methylation and epigenetics is emerging as superior to standard blood work for nutrient absorption optimization
  • Pre-procedure preparation (peptides, red light, hyperbaric oxygen) significantly improves surgical outcomes and reduces downtime by up to 50%
  • Beauty and functional medicine must be integrated; aesthetic results fail without addressing inflammation, hormonal balance, and cellular health
Trends
Shift from filler-based aesthetics to regenerative medicine using amniotic fluid stem cells and exosomes for tissue repairPersonalized peptide protocols becoming mainstream for sleep, cognition, appetite control, and nervous system regulationGenetic/epigenetic testing driving customized supplement formulations instead of generic multivitaminsPre- and post-operative optimization protocols becoming standard in elite plastic surgery practicesIntegration of cardiac imaging (Cleerly heart scans) into preventive health screening for aesthetic patientsWomen's hormone optimization (testosterone, vitamin D) gaining acceptance as alternative to psychiatric medication for burnout/mood issuesMicroneedling with RF and chemical peels being repositioned as foundational treatments requiring 6-12 consistent sessionsFunctional medicine practitioners building aesthetic practices rather than traditional dermatologists/plastic surgeonsTransparency in supplement sourcing and third-party testing becoming competitive differentiatorWearable technology and personalized data driving future of peptide dosing and cycling protocols
Topics
Regenerative aesthetics and stem cell therapy for under-eye treatmentAmniotic fluid exosomes versus traditional dermal fillersPeptide protocols for muscle gain, sleep, cognition, and appetite suppressionGLP-1 agonists (semaglutide, tirzepatide, retatrutide) and glucagon combination therapyMicroneedling with radiofrequency for collagen induction and neck rejuvenationRenewva adipose matrix for fat pad preservation and regenerationMicroneedling with topical tranexamic acid for melasma treatmentNAD+ injections for mental clarity and energy optimizationGrowth hormone peptides (Ipamorelin, Tesamorelin) for muscle preservation and sleepNervous system peptides (Semax, Selank) for anxiety and benzodiazepine alternativesGenetic testing and epigenetic supplementation protocolsHormone replacement therapy for women in perimenopause and menopauseCleerly cardiac imaging and soft plaque detectionRed light therapy for circadian rhythm and collagen productionTopical retinol formulations and double-bonded retinoid technology
Companies
Tonic
MJ's regenerative aesthetics and functional medicine practice integrating cellular health, peptides, stem cells, and ...
Function Health
Comprehensive biomarker testing company that MJ's lab now competes with, offering 135 biomarkers at comparable pricing
Jeviti
Mobile phlebotomy service that sends technicians to patients' homes/offices for blood work collection
Cleerly
AI-powered cardiac imaging company providing 3D heart and artery visualization with calcium score and plaque density ...
Renewva
Adipose tissue matrix product derived from human tissue bank used for fat pad regeneration and facial volume preserva...
Sculptra
Poly-L-lactic acid injectable that builds type 1 and 3 collagen for skin elasticity rather than volume
SkinBetter Science
Topical skincare brand recently acquired by L'Oreal; MJ uses their products in practice with 5-year formulation prote...
One Skin
Peptide-based skincare brand with clinical research backing; MJ recommends their OS-1 serum and body lotion
Young Goose
Biohacking skincare brand featuring double-bonded retinol that doesn't cause peeling and NAD/peptide-infused formulat...
Agent Nateur
Clean skincare brand offering hydration products; MJ recommends for accessible, non-prescription skincare
Boncharge
Red light therapy device manufacturer; MJ partners with them for travel-sized red light devices
Clean Label Project
Third-party testing organization that tested 160 protein powders and found nearly half of top sellers contained high ...
Jackson Memorial Hospital
Miami trauma hospital where MJ worked in trauma and critical care before transitioning to regenerative aesthetics
Kendall Regional Medical Center
Miami trauma hospital where MJ worked in trauma and critical care before transitioning to regenerative aesthetics
People
MJ
Regenerative aesthetics expert and founder of Tonic; former trauma/critical care physician now specializing in cellul...
Liz Kennedy
Friend who introduced the host to MJ; described as having exceptional skin and serving as case study for regenerative...
Miguel Mascaro
Plastic surgeon who integrates functional medicine protocols (peptides, red light, hyperbaric oxygen) into surgical p...
Ivan
Functional medicine doctor who introduced the host to peptides and helped treat burnout through hormone optimization ...
Quotes
"You cannot be great on the outside if the cells are not doing good on the inside. They just go hand in hand."
MJEarly episode
"No cream is going to save you at the end of the day. And if you're chronic inflammation, you're kind of fucked."
HostMid-episode
"Regenerative aesthetics is all about your before and after. Because the results are not there in Sydney, like filler. We're talking about 12 weeks, right? 16 weeks sometimes."
MJMid-episode
"We are building a next generation of clinics. We want to be the future. We want to show people that health and beauty belong together because it starts from a cellular level."
MJLate episode
"Peptides are short chain amino acids that send different signals to your body. So you can take a peptide for gaining more muscle mass, having deeper sleep, better cognitive function, better recovery after working out."
MJMid-episode
Full Transcript
So guys, I'm going to date myself every year, but if you are, you know, a late millennial, you know about the Archie comics, and there was this beautiful character in it called Veronica. Well, my friend Liz looks like a real-life Veronica. Her face is perfect. She's beautiful. She's got great skin. And so when she moved to Miami from LA, she goes to me, I have this incredible injector. You need to meet her. She doesn't believe in traditional fillers. She does everything like with rejuvenating aesthetics. And I'm like, wait, what? Who is this girl? And so that's how I met the amazing MJ. And MJ, I was so excited to sit down with you and tell my audience all about where the beauty industry is going, what are the alternatives and how can we age gracefully? Yes. So let's throw fillers out the door and let's welcome regenerative aesthetics. Regenerative aesthetics has been, well, a game changer in the industry in general. I think when I first started people are like, are you crazy injecting stem cells under eye? I'm like, but what are we going to do? Blow them up with filler? Listen, I want to talk about the stem cells piece because you told me about it. Clients are ordering it. So they're mesenchined stem cells, correct? They're amniotic fluid. Okay. Like basically pure amniotic fluid. And what they've done to regrow the way they can repair the under eye, the fine lines that tissue, the hollowness has been incredible. It's one of our favorite. Yeah. It's something that we always do in the practice. And when it comes to that, where are you sourcing the embryonic stem cells? Well, that's from a lab here in the States. Okay. A company dear to me that I work with. And that's kind of top secret. Yeah. And of course. And are they testing the product before it's getting sent? Oh my God. Yes. Oh my God. I'm really going to test it. We want to make sure we're not injecting something. What if somebody carries this or in a marker or a disease or something? Of course. Of course. Not only that a big thing to look for is stem cells is finding patients who are not previously vaccinated. That's been huge. The shortage on stem cells. And I think that that's what makes our stem cells so expensive. Right. To find that little niche, to find that is quite difficult. Yeah. Because just so people are listening, even if you haven't been vaccinated, but you take in a stem cells or something else from somebody who has been vaccinated, you can still get the spike protein. And there's this whole theory out there as well about vaccine sharing. I'm not going to tell you guys about it. You can go look into it yourself. But it exists and people are seeing it and researchers starting to show it more and more as well. So you really have to be discerning when you're getting something which is from somebody else donated, even fat like Renewva, which is the product that I love. I love. I love I can't live without Renewva. So how long ago did you start doing stem cells for the under eyes and seeing the results in me like this is amazing. So maybe four or five years ago we started stem cells under the eye. I think four or five years ago stem cells were still so hush hush. Like it was like, what are you doing? And why are you doing it? I think we've come to a point where people are more open to human tissue because that's essentially what it is. I always joke I'm like, if anyone sees the back of our office and all these medical freezers they're like dead bodies. What are they? What are she housing here? But it's all Renewva and it's all stem cells. And I'm Yonic fluid and it has been a game changer in the regenerative space. Do people get bruising under the eye when you put it in or can you get like, it can happen. Bruising can happen. I think anytime we're working with a needle, the entry point is primarily where they would ever get a bruise. We do use the cannula always under eye. Just, you know, no sharp objects. We don't need to burst any tiny veins that we have there. And that helps minimize bruising. It's really rare. I don't think I've ever had like a huge black under eye. And generally because I will show people around any of our neighbors, right? What are some of the things people are seeing right away from using something like stem cells under the eyes? So that's great. I have people come into my office all the time and they're like, we don't see it. I don't see it. It regenerative aesthetics is all about your before and after. Because the results are not there in Sydney, like filler. We're talking about 12 weeks, right? 16 weeks sometimes. So we have the patient usually on day one that you do the procedure. We already schedule you for eight weeks. I'm like, don't call me until eight weeks because nothing is going to happen. Your under eyes are not going to be better. Your knock on a sea results come back eight weeks, 12 weeks. Let's take pictures. Let's reassess and then go from there. And it's like time and time again. The patients are like, we don't see it. Oh, there's the before and after. Oh, there it is. You got to wait for. Yeah. And how much does treatment like that generally cost? And how long does it last? We do the stem cells under the eyes for 2,500. We do our IV stem cells for 6,000. And the IV stem cells are exosomes. The IV stem cells we go back to the amniotic fluid, we I really love what the amniotic fluid. And yes, essentially, there are exosomes. They're all, you know, yeah, they're all essentially exosomes. But the purness of the exosome or the stem cell, I think is where. Well, yeah, makes a difference. It's all made of the difference, right? Like how many times they're, you know, they make them in the lab and then they multiply them? How many times was that multiplied? What's the strength? So you want something that's more multiplied or less multiplied? Less multiplied. Oh, yeah, because it's still higher. You don't want to think hyper, hyper, hyper, hyper. I know how hyper it's either. MJ, I also want to go back a little bit. So how did you get started in the, you know, kind of the beauty space? What was your background? OK. It all started. My medical, like my medical background started in trauma and critical care for years and years. Being here in Miami, I worked at Jackson and Kendall, those are the two trauma hospitals, yeah. And we love that, but that's very, I love the quickness of trauma, you know, the critical thinking, but high cortisol levels. So after some years of not having a lunch break, I decided that I wanted to make women feel happy and confident and change from this sometimes sad setting into a more positive, positive. So we started aesthetics and quickly I was bored. Yeah. So not to challenge any or not to downplay an aesthetic injector, but I, there was no more lab reviews. There was no more of that critical thinking. So I started thinking, OK, how do I merge these two worlds that I really love without killing myself? Right. And I think the answer was cellular health. That was the answer. Still practicing medicine, because what I do in my practice today is every day I'm looking at labs, I look at images, rather it's MRI brain scans, that we send patients to do clearly hard scans. Why am I MRIs and brain scans? Well, we want to get the full picture. And I think that's the big difference with tonic. We're not just doing regenerative aesthetics, like on your face. It's your whole body. It's your systemic, we are our cellular health. So if you're great on the outside, you can't be, well, actually, actually, rephrase that. You cannot be great on the outside if the cells are not doing good on the inside. Right. They just go hand in hand. How long has beauty and medicine been separated? It's like, here's a medspa on here's your provider, your primary. Why? It all starts with cellular health. You know, it's so funny you're seeing that, because everyone always tells me, hey, you have great skin. And I was like, it's not a cream or a topical down putting on my face. I really take care of my inside. You know, I'm having enough healthy fats. I'm taking phospholipids. I'm making sure I'm getting enough sleep, water, lacidration, all of that stuff that makes a difference to my skin tone, texture, how I look on the outside. And I always say, no cream is going to save you at the end of the day. And if you're chronic inflammation, you're kind of fucked. Yeah. Well, topicals are a whole thing in themselves. But yes, cellular health comes first. If your hormones aren't optimized, if you're not sleeping, if you're not getting the right nutrition, and if you have no muscle mass, forget it. That's not even going to be a muscle mass. Because you also do peptides, and we're going to get into later into the episode as well. So what is the one most underrated biohack, you think? Okay. Well, it's not really a biohack, but I think it's just the most underrated regenerative treatment. And that's micronedally. You know, you told me about, did you do micronedally? I was like, I just got a fat transfer back later this year. I don't want to melt the fat on my face. So tell me a little bit of my micronedally. Well, that would be RF micronedally radio frequency. But just let's go back to basics, micronedally. I think it's a golden standard that is so overlooked and under treated and prescribed incorrectly to patients. Okay. There's this whole 400 percent increase in collagen with each micronedal treatment. That's what you read on Instagram. But that and TikTok, we love TikTok for medical advice. But when you get into the actual medical study and you start reading, I think, well, first of all, it was six treatments back to back monthly that caused the 400 percent collagen increase. Back to back, meaning once a week, once a month, once a month, once a month consistently. So when we're looking for regeneration and especially on the neck, this is the number one thing people come into my office for, the thinness on the neck, you need to be micronedally and you need to do it correctly, which is six to 12 sessions. Minimum in my office, I make my patients commit. You know, because I'm 42 now. So this was the first time ever I'm like, dude, what happened to my neck? And obviously I'm not a candidate for a neck lift or anything like that. But I was like, what can I do? Just start preserving my neck and making sure this little lines don't get really prominent. Okay. We're going to take some before and after. We are. We're going to do some monthly micronedaline. And we're going to reassess that in a year. And when it comes to somebody like me who's like, hey, MJ, I want to keep the fat on my face. I want to keep the volume on my face. I do not want to damage my fat pads. What do you recommend for us, for somebody like me, when it comes to my micronedaline, what is the technique, the duration, the type? Well, someone like you who tends to be on the thinner side and can lose fat pads, it's still renewable. We want to keep regenerating that fat pad. That's the first thing. We want to repair, regrow and regenerate it. I want to tell people what is renewable. I love it. Okay. Renovas, one of my favorite products, guys. We love renewable. We absolutely love renewable. We swear by it. We swear by it. Our face is filled with tiny little fat pads. And when you're a child, you look so youthful and full and plumpy and just want to hug you. Yeah. And then what happens is that those fat pads get smaller and smaller with age. And we look like a little skeleton. So what we're trying to do is preserve those fat pads as much as possible, especially in your case, someone who is thin and tends to burn so quickly, we want to keep that volume. So renewable isn't adipose fat matrix, which will integrate with your actual fat pad. So it comes from a tissue, a human tissue bank. And again, same thing that we discussed before, it's tested for everything. All of our, anything that comes from human tissue bank is tested and comes with its own paperwork, you know, no HIV, no hepatitis C, no hepatitis B, all that stuff comes alongside it. And it just re-grows your re-grows and integrates with your fat pad. And for people that you've given, put renewable in their face for, have put renewable in their face, how many, how long does it take to see results from the day you put the renewable to when you actually see the fullness and the plumpness? Oh, I love this question because renewable is instant. The fat is there. It's a volumeizer. Okay. It's there. But the full result you don't see right away. See, at the minute you inject it, then it kind of goes down. Yes. And then it goes down and then you're kind of waiting. And it's about 12 weeks, I would say is your end result. Okay. And I still think even renewable needs to be built a little bit. Like, yeah. Two or three rounds sometimes. Again, 12 weeks apart, I'm really scared of blowing people up. Yeah, yeah, because when I ever test you, like, no. Still sculpting. Yeah. Yeah. Everyone wants to be like, I want to do it now. Like, can we let this regenerate and see what it looks like before you look like a blowfish? Yeah. 17 vows of sculptural. Because it's not something you can dissolve. It's not a filler. So, yeah, it's not going to dissolve. That's important too. It's going to integrate with your tissue. And that's important for safety. Yeah. People need to know that they're going to a provider who knows where to put this product because it's there and it's not going anywhere. And then when it comes to renewable, unlike sculpture where you need to build multiple times, right? Like, I mean, I personally have not loved sculpture because I think you'd have such a thin face. It takes so much sculpture to even, like, get to that point. But, Renewa, I've absolutely loved. What's the difference between the two for anybody listening? I think my personal opinion, are you waiting for sculpture to fill your face because it's never going to do that? Yeah. So, but I think you love Renewa because it does give you a little bit of volume. Yeah. It's replacing the fat pan. Sculpture, all sculpture does is build type one and three collagen bands. So people think that it lifts and pulls because we put it behind the line of ligament and it does give a slight little tug. But the tug is from the tightness of the collagen bands that now help with the elasticity. That's why when we do sculpture in the practice, we record the patient's elasticity. Not where the face is sitting. We want to know is those collagen bands making that skin stick back to place? You know? Back to place, yeah. I think if patients don't understand the sculpture is primarily for collagen production, type one and three, for elasticity of the skin, for skin quality. And if they're waiting for volume from sculpture, they're going to be disappointed every time. So, if somebody comes to you, how can you tell if they're patient, they're a candidate for sculpture over Renewa? Is it the end goal? Is there how they want to look? It's usually both. Okay. It's very rare that it's not both in my healthy aging plan for them. Because again, one addresses fat pads and the other one collagen. And those are both things when you think of regenerative aesthetics that you want to keep going. Yeah. And you cannot do Renewa under the eyes, correct? No Renewa under the eyes. Could it be off label? Could I have a might of done it before? Yeah, maybe. Has it worked for people? I think it works. I feel colonists. I feel colonists. Yes. In an extreme, tiny amount in the right plane and very hyperdiguted, tiny amount. Okay. And just underneath, not on the top, let or anything. No, no, no. Okay. I haven't done it on the top. When you guys get patients in, especially in your LA practice and stuff, and obviously you're expanding, I'm excited that you're going to be in Miami more, when you get patients in, what, when you're looking at their labs, what are the first type of markers you're looking at and trying to assess? Before you even want to touch their face and get them started? Yeah. We do have a full panel and it's actually, I can't even say this because, okay, we actually are competing with function health. Yeah. Okay. It's amazing. But why do you work with him? Yeah. So you're competing with full panel. Okay. Okay. So we now have a new full panel that competes with function health because, for quite some time, our patients were coming in with their own labs and our lab just wasn't able to do that amount of biomarkers for that price. So I think after much negotiating my lab, and I think the owner getting tired of me calling him, we finally negotiated a full lab panel. So we try for the patient to do that. Again, it's the same price as function. It's very well priced for the amount of 135 biomarkers. And we try to start that and that's the whole health. So that's what you start with and then you're looking at some patients and doing like body scans and MRIs and stuff before you sit to the point and start injecting them. No, we don't have, we don't make patients do a whole markup. I have patients who just see me for peptides. I have patients who just see me for stem cells. I have patients who just see me for GI for gut issues where we do gut maps and figure it out. I think it's very much based on the patient's needs. Sign symptoms, yeah. Let's talk about peptides as well because let's take peptides from you and she loves them and she spares by them. What are some of your next? Yes, I love peptides. I love them. I always cycle in them and out. I love them. I started peptides six years ago and people are like, you're crazy and I'm like, this is going to be the new thing. And it is, you know, and so for anybody listening, what are peptides? Peptides are short chain amino acids that send different signals to your body. So you can take a peptide for gaining more muscle mass, having deeper sleep, better cognitive function, better recovery after working out. You have peptides at GHKCU for, which is a copper peptide known as a beauty peptide. We're also realizing more and more that peptides beyond just the service can be tied to things like fertility, longevity, so many different things. And essentially it's a, it signals to your body to do certain things. So it's a chain, amino chain is normally 12 to 26, correct? That's how long the chain is. Thank God, I know my shit. And different ones need to be stacked in different ways. And the best thing to do with peptides is obviously you cycle them in and out. So you take a protocol, you do it for two months, you stop because you always want your body to not be reliant on something that is external. You want your body to also be remembered how it's supposed to function internally. Yes. So there are some, there's a whole debate on peptides, there's a whole debate on bio-regulators. Oh, yes. And NAD. Yeah. There's a base on how long you should take these and cycle them. I think when it comes to let's say NAD, NAD for me has been a complete game changer. With my brain fog, mental clarity, like I can physically feel it after subcutaneous injections for three months. There's this whole thing of do you have to cycle it, do you not have to cycle it? I don't cycle it. Some patients though do do better with a motzi cycle in the middle. Okay. So it's so peptide is not this standard protocol. It's, we're still so individualized. Of course. Even those receptors are individualized. So I really think the future for peptides is more personalized data. I think in the future we're going to have more personalized, like wearable, wearable and track it. Yeah. Wearables that will help us better understand. Understand. Understand what those short chain amino acids are doing in our body to be able to live. What are some of your favorites? Ooh. Hmm. I can't live without my NAD. Yeah. I can't. I cannot live without my reddit trotide. Reddit trotide changed my life. What is that? Reddit trotide is the third GLP1 agonist that tries appetite. It's stronger than trotide. And I should say stronger has an extra agonist. Okay. So we have trotide is GLP1 and GIP. And reddit trotide is GLP1, GIP and now we added glucagon, which is a hormone in the liver. That helps support the pancreas. And for me, who I was so frustrated seeing patients come in and out of my practice, just living optimally better health, more muscle mass. And I was on some of gluteide. I was on trisapotite. So this wasn't working. It wasn't working. It was the muscle mass essentially. This one also doesn't make you lose muscle mass. But it wasn't working for my metabolic health. And it was working for everyone else's. And that was so frustrating. So when what a trotide came out and something actually worked for me after 3,500 on my patients, it was working. I was like, thank you God for glucagon. What are the ones that are you loving? I do love any of the growth hormone type of peptide. At the Marlin TGZ. I think everyone can benefit from a little growth hormone stimulation, better sleep, better recovery, maintaining muscle mass. It's a huge mistake, I think, to throw people on GLP1s and not to put them on a growth hormone. Of course. Because the growth hormone increases the granite, which does increase your appetite. You want to balance it. You don't want the patient to not eat. You need them on a high protein diet. If you are taking protein powder, you definitely need to hear this. The Clean Label Project tested 160 different proteins from different vendors and brands across the US. And you're going to be shocked at the discovery that they made. Nearly half of the top selling proteins in the US tested high for lead. And if you're somebody who consumes protein powder daily, this is something you have to be concerned about. And to make matters worse, most brands do not value transparency and will not reveal their test data online. And I want my community, like myself, to always make an informed choice of what they want to be exposed to and how they consume their daily protein. And that is why I love puri. I also sat down with the founder and had a full honest transparent conversation with him about how they source, how they educate their consumer, and also what their products offer on the market, which sets them apart. Their puri PW1 protein tastes absolutely exceptional and you know you're not getting the gunk of heavy metals in it to start your morning with. And that is why I absolutely love puri's PW1 way protein. That is how I choose to start my day every morning. Every single batch is third party tested by the Clean Label Project and no product is ever sold unless it passes these tests. And puri is one of the only brands in the US that has the Clean Label product certification on their products. And that is only possible because they make all their third party testing completely transparently available to the consumer through a QR code where you can track the exact journey of the batch of product that you're purchasing. So you guys can see for yourself exactly how clean the PW1 that you're consuming in the morning is. Every single serving gives you 21 grams, a minimally processed high quality bioavailable protein. It comes from pasture raised cows, no GMOs, no hormones, no herbicides, no pesticides, and definitely no heavy metals. So this means I can start my day with confidence knowing I'm having something super clean to support my skeletal muscle mass. My personal favorite flavor is the Berber and Vanilla, no artificial flavors and no funky aftertaste. To make sure your daily protein powder is not hiding any nasty chemicals and they're not being open and transparent with you. So if you want something clean, delicious, and bioavailable with the transparency, go now to get this amazing discount. P-U-R-I dot com puri dot com slash bio hack it. Switch over to puri's PW1 protein and you can thank me later. How many of your patients like women, if they show low testosterone levels, are you putting them on testosterone? Yes, no women. Cream or injections, both. Okay. And I think it depends on the patient's lifestyle. What are they open to, right? But both testosterone and women, like, why is it taking us so long? I don't know. And it's pretty cool. What's going on here? It's wild. So I basically, 2025, like, we should be on. Women needed. So for example, I came back from the summer. I've been an extreme burn out. I use this. They're also a competitive function. How does it called Jeviti? Okay. It's an incredible blood work company. They actually come to your, they send the flambotinous to your house or your office or wherever you want them to come. So do we? Yeah. Look at that. Right? It's annoying. It's annoying. It's annoying. I don't want to go to a quest and sit there and queue, right? I need you to come to me. So I really like this company. I did my blood work and I wasn't feeling well and it came back. I was in full burn out. I was in a regional fatigue, no vitamin D, even though I was in the sun all summer in Europe. Testosterone was totally shot, all of that stuff. In a dear friend of mine, he's a functional medicine doctor. Ivan and I said, he's actually got me into peptides years ago. I said, girl, you're going to have to go on testosterone injections. And I was like holding on from an, I'm like, Ivan, like, what do you mean? He said, you have to start injecting vitamin D testosterone. MJ, I will kid you fucking not. I started doing it in three weeks later. I'm like sitting in the car and I'm like, I felt like myself. I knew I was having, I was chronically crying. I would burst into tears. My poor podcast producer was like, literally, I'd get off a show and start like bawling. I was completely unregulated. I was like, what's going on with me? And I see this amazing therapist. And therapists, you need to go on SSRI's. And I'm like, I'm not going on SSRI's. When I know in the health and wellness space, it's my hormones. My, my, I'm having my bodies not observing nutrients correctly. I'm going to do this my way. I kid you not within three weeks of me doing certain IVs that I did with, with Ivan. And then starting on peptides and starting on vitamin D and testosterone, I started feeling like a new person. And I was like, this is what happens with the traditional medical field. Like, your therapist can be amazing, but they don't know about nutrition. Yeah. They don't know about supplementation. They're not reading your blood labs. They don't know about the inflammation in your body. They do not know what your, why you're having this deficiency. Okay, if you're having burnout, what's going on to support your adrenals? What's going on to support your liver? What's going on to support your thyroid? And I was like, thank God, I know so many people in the functional space that are close friends of mine that I can go to and say, hey, I'm having this problem. Can I come see you? They're like, yes, we're going to fix you. And yesterday I went in because I hate injecting vitamin D myself, because I drive to the clinic and my police inject me. And the dog, he saw me. Ivan, he said, how are you feeling? I said, I feel like myself again. So, so great, so great. But this is what happens with a lot of women after 40, because you start going into paramedics and you're hormones start fluctuating. And that is why I think the research I saw was like one in four women or one in eight, I have to get the exact quote though, a number are put on SSRIs because their hormones start fluctuating. Yeah. And then they start, they think they're going nuts. They're not. It's just hormones. But there's something that you touched on that I think is so important. I want to jump back into it. And that was nutrition and supplementation. We are so old school in treatments. It's kind of crazy and I think it's traditional medicine spot. We now do genetic testing for supplementation. Wow. So, yes, in our practice. Okay. So, you know how I'm sure your counters full of vitamins throw them all away. Let's test your DNA. Yeah. Let's look at your epigenetics. And then we create a special supplement based off your genes. And you work with a lab to then do that based on your needs. Yeah, why work with a company who does that? Amazing. And girl. And you know, you want to talk about feeling brand new because our blood work changes. We're so used to treating. Of course, it's a job. Yeah. Exactly. We're so used to treating all my magnesium level based off of this blood work. But where's the genetic deficiency? That's what we need to repair because we don't know if you have methylation. We don't know if you're taking 27,000 vitamins. You're not absorbing them. So, what are we doing? The epigenetic supplementation game is a game changer. So, somebody comes to you. How do you test them? We swab. We do a cheek swab. It gets sent to the lab. It gets run through a testing process. They bring it back. They give you your whole DNA results. They tell you this is this and this is the nutrient that's missing. And then they can formulate for you either capsule or powder, which I love because I'm over capsules. I prefer to have a heartache. Yeah, a powder. They especially formulate that for you. And we retest every six months just to make, I mean, genetics are forever, but we do want to show you the difference. Yeah. They're absorbing, responding to it and stuff. Correct. And besides, that's amazing. I didn't even know that. And so, we're going to get you on it. Yeah. I want to do this like genetic testing for my macronutrients and bioavailability. But then, basically, when you're getting somebody, so this is what I'm thinking. When you're getting somebody who's chronically inflamed, uninflamed, you're improving their mental health break. Because women are like spiraling. Hormones might be deficient. They might need vitamin D. They might need testosterone. And when you start treating them aesthetically, they're probably much happier, A, with their results and the results last longer. Because their body's not so much in fight or flight. And they have a better relationship with themselves. In my practice, education is key. When we can empower the patient with education, like on this whole testosterone, I want to be a bodybuilder thing, it can, it just empowers them to make their own health decisions. Right. And that's, I think, the difference. For so long, we've been separating beauty and health. No, it's the same. And they're one in the same. It starts at the cellular level. And I think when women start feeling better on the inside, they glow on the outside without a laser treatment. They just feel so much better and they have more confidence. And that's really, it starts at the cellular level, the cellular health. And then when you are treating these women and you're getting them bounced out and they're feeling better and stuff, do they, they obviously must like their results more because they're in a better space mentally. You know, some women, I've seen the same with friends, they're like, we want more of this, more of this, more of your like, girl, you don't need more of that. You need to like reframe her, you're looking at yourself in the damn mirror. Yes, sometimes I'm like, it's, sometimes we have to, we just have to say no. No. It's a breakup girl. Like, cry it out, it's not lip filler. The filler is not going to affect you. The girl, it's not, it's not that, it's not that. Cry it out, it's, you don't need more lip filler. Sometimes it's no, and it's mental. Like, you know, mental health and there's so many times patients come to my office, I think to talk. Yeah, yeah, they're like, we like a friend. Yeah, they're like, I think I need filler, but really, I just need therapy. Yeah, yeah. What are some of the treatments people are coming to you for the most right now? We're, we're doing a lot of stem cells. We're doing a lot of runova. Love me, some runova. We're doing a lot of peptide protocols. And for some reason, there's a spike in clearly hard scans. We're doing so many of them. Don't tell me that. Tell me, tell me what's up. What is that? What is the, the heart here? So clearly, hard scans. It's a CTN, Joe of your heart that helps you figure out your calcium channel score, which I'm sure you're familiar with. Yeah. Yeah. And then they also have a third, it's like an AI that takes images of your heart, but we can now visualize your heart and your arteries in a 3D. Okay. So I can now scan your artery almost like a straw, like if I'm looking into it, I can see the wall from top to bottom. And you can see your practice? Wait, wait, wait, no, we sent them to an imaging center. Don't worry guys, but I do, even though a radiologist reads it, even though the AI reads it, I actually am so old school. And I think this is from trauma because you have to review your patients chest x-rays every morning. Absolutely. You review their labs every morning. I actually review every heart scan. And they make fun of me in the office. But I actually, my trauma training is coming through guys. Leave me alone, I need to know if it's soft plaque or I just need to review the scan one more time. But wait, this is incredible for cardiac health. If you can drop dead of a heart attack and have perfect labs because soft plaque, what is soft plaque? Oh, okay. We want to know. Oh, okay. So there's no density plaque. There's soft plaque. Stenosis comes from heart and plaque, right? That's not dangerous. It's dangerous in itself, of course, it can close the more dangerous as the low density and the soft plaque. That's what could dislodge, not the hard plaque that stuck to the side of the walls. So when you're looking at stenosis, you have to then break down that stenosis, which the AI does, of the clearly. And it will show you exactly the percentages of what is soft plaque, what is low density plaque, and what is stenosis. It's just, it is such a smart scan. Amazing. It is such a known. And if you, well, we have one patient who had a horrible scan, started some medication, some protocols, some peptides, and scanned again, almost a perfect scan. Really? Yes. So I have to give you the before and after. Yeah, I want to, I want to use the before and after to layer over actually the show. Yeah. Yeah, because that was impressive. For you building something that is so kind of new age, because this is still very like new age, people are now starting to kind of get educated about it. Peptides are now kind of becoming a thing. What were some of the challenges for you to build tonic? What worked? Well, didn't work? What has been hard? What has been easy? Getting patients, I think the biggest challenge is I, I think they see me on Instagram and they don't know my trauma background. So they're like, oh, another nurse filling lips, you know? And then they come to my office and I'm like, where are your labs? Let me see your labs, pull up your images. And they're like, wait, I didn't come with all of that. And I'm like, yeah, I know. But this is how it works for me. Yeah, this is more than lip filler appointment. This is more than a peptide protocol. This is not a green market where you're, you know, just fine. And injecting crazy things like, no, we do things here very organized and scheduled with labs. And I think people have taken beauty so lightly and then medical so separate from that. So putting them under one roof, it's hard for people to grasp the concept. But I always tell my employees, like, we are building a next generation of clinics. We want to be the future. We want to show people that health and beauty belong together because it starts from a cellular level. And looks it's way up. Yep. And we want you to, we want you to decide how you age. What is beauty, you know? And when you think about beauty, right, and Jay, in your opinion, what is beauty to you? Beauty is external, but beauty is also internal. Beauty is so many things, right? Your mental clarity is beautiful. How you present yourself and with confidence is beautiful. Are you healthy? That's beautiful. Muscle mass is beautiful. Do you take care of yourself? Beauty can be so many things. I think, I mean, I love the external stuff of it. I'm a woman. In my 40s, I really appreciate age and beauty. And you're beautiful. Thank you. So I think beauty for me, if I think about that, is really about having this grounded confidence within yourself and having what I'm trying to currently work on is regulating my nervous system. It's just safe in my body. Yep. Trust my decisions. It's to have confidence in the decisions that I make and know that I'm okay. And I think that for me, with all the external help from you, Miguel Muscar, who I love, my favorite plastic surgeon, obviously all that combined helps, but I think it really also comes from the inside out. And more I know about my body, my chronic inflammation, but my mental health and having a regulated nervous system has a lot to do with how I show up externally. Because you can have all the beautiful skin and the fillers and the Botox in the world. But if you're erratic and not confident and you cannot show that as a woman, right? Of course. And that's internal work. And we have peptides for the neurotic women. We have peptides. We have peptides. C-max and slank. Let's work on your nervous system. Girl, we have peptides for that. And why do you love those two and how do each one of those work? Ooh, I love them. I love them. First of all, I love them together. Okay. And they've actually helped so many of our patients even come off benzos. Wow. Even, yeah. They're really, they're really, really, I think, underrated or not talked about enough, right? Right. Like, all we hear about is Tessel Morlin and... Appa Morlin and stuff like that. Yeah, yeah. Tell me about these two and how each one of them works and why should they be combined. Okay. C-max and slank should be combined. And I think they can be easily given, right? Not injected. They can be given in an nasal spray. Okay. A lot of people turn away from peptides because of injection. I, I, yeah. I like, I can't do it. I'm like, you can do it. Your health... It doesn't hurt at all. I'm like, your health deserves it. Like, it's a needle scare. Yeah, yeah, yeah. And then we are like invested in these tiny little, I mean, they're tiny. They're tiny, it's like that. Yeah. We buy the most expensive needles for our patients, because we're like, it's not scary. But I think helping people learn how to control their anxiety, because anxiety is within. Absolutely. But if that peptide can help assist that person, rather it's come up, Benzl, sleep better, study, be more focused, which all of that, a slank and C-max can help with. So if you're struggling with anything, neural, like just talk to us, because there is a peptide for everything. That's the most amazing and, ooh, amazing and incredible thing about peptides. How long can somebody be on a C-max or slank? Is it to have to cycle it, to the knob to cycle it? You know, because with growth hormone stuff, we have to cycle it. Yeah, we're still cycling it. Okay. C-max on slank. I recently read a study that you don't have to, but I think, anytime we're talking about receptors, can a receptor get tired? Like, we don't want to be stimulating. Right. And we need to take them in. And we need to take them in. Yeah. Yeah. So I think taking a break, anyways, I is still my favorite. And I just see you and founder, how do you manage a company and also keep balance in your personal life? And how do you, I want to ask you this. If I had access to all the shit that you've access to, I'd be doing something every single day. How do you knob? Because I'd be in there testing everything on myself. Thank God. Oh my God. We don't work in regenerative aesthetics. Let me tell you. It's my patient's fault. It's the 3,500 patients that I see that I do full labs for review scans for. That's a lot for one provider over a year. But I don't have that much time. I'm very disciplined with my time. So what's your, when's your birthday? May 24th. I'm a little Gemini. You're Gemini. Yeah. I'm pretty disciplined with my time. And I try to pick the peptides that fit best for my lifestyle. I don't really have too much time to do too much to be honest with you. Yeah. So get on the plane, sleep. You got to like train yourself. It's time to sleep. Yeah. You wake up in the morning. You do your NAD and you go to work. You maybe get to train you're between. You see patients in Miami. You work. You get the night flight. You go to LA. You land. You're like, it's now it's late at night. You're confused. But you can use the peptides to help assist. And what about the beauty stuff? Because I would be taking my stuff with stem cells and exosomes every month. OK. I would have all of that. Yeah. Well, in my personal life, resistance training, muscle is medicine. That is like the number one organ for longevity. Yeah. So this is medicine. Man, consistent red light therapy. Why do people, why is it underrated? It's like micronedity. So incredible for you. A general why? Circadian rhythm, college and production in Laudcocity. Everything. It's underrated because people are not consistent. Totally. That's why it's underrated. What do we do when we travel? Because like, I'm gonna the Middle East for a month. I love my red light device. What do I do? What do you mean? I normally stand in front of it every morning. Oh, what do you do? But you don't have the little tiny cube that you could travel with. But I should get one. Yes, there you go. That's what you do. You take the smaller one. A brand that we worked with and partnered with is actually Bonchart. They have incredible red lights. We're actually going to reach out to Bonchart and be like, give me a red lights travel with. A smaller one. Yeah, because it's smaller too. For anybody listening, red light is incredible to also help with your circadian rhythm. The more we learn about our body, the more we understand inflammation and markers you need to balance and regulate your cortisol production. Your circadian rhythm has so much to do with that. So getting like natural light in the morning, if you cannot get natural light first thing in the morning, then doing things like red light therapy really helps your body. Of course. It tells your body when to wake up, when to go to sleep. It helps ground you. It helps regulate you. Obviously, it produces, I think, 30% more collagen have done consistently is that. Yes. And the word consistent me is the key here. Yeah, because every single day. Yes. My patients always send me devices this, that, and I always the new face. The red light mask. You're like, how often are you going to do it? That's my first question to them. Are you going to use this consistent? If not, then forget it. If you're going to microchannel your face twice and throw it in the, forget it. Do me a favor, buy another peptide and save a whole new device. So consistency is definitely, it's the key. It's the key to longevity. It's everything, right? Consistent working out, consistent red light, consistent peptides, consistent, consistent, consistent. So I want to get three tips from you to the audience with that they can apply to their life, both from a beauty standpoint, personally, professionally, three tips. OK. Three tips in the regenerative, aesthetic space. The first tip is to micro needle your neck from now until you die. Just a start. The second tip is, and this is a big one for me, it's topical creams. Learn your ingredients. We didn't touch upon topical creams. So can we talk about that for a minute when we thought topicals? What are some of your favorite brands, products? What's really working? What's bullshit? Yeah. We've been with Skimbetter for quite some years. They were just bought by L'Oreal. Formulations might change now. Right. Which was my first question. But for now, we still are using Skimbetter Science. I think they're in a five year, like, can't change any formulations, can't cheapen it down, you know? I mean, that's what the bigger companies do. But I think my biggest pet peeve, and what I hate the most, is when patients come in, and we do a skin assessment, and they're like, well, I don't want to buy that, because I have all this stuff at home. I'm like, perfect. Do me a favor. Go home, send me pictures of everything. Let's go through the ingredients. They never know what anything is. They never know what it works. If it works or it doesn't. And they'll literally have 17 moisturizers. And nothing to work on the pigment. And melasma, and they're in my office for pigment. I'm melasma. Yeah, you're like, hello? Did you read the ingredients to no one ever go through it with you? Every patient? We'll go back to education. Every patient who comes into my office, if you're there for skin health, not only am I talking to you about products, I'm talking to you about ingredients in the product. Correct. And I don't care if you buy it from me or not. If you have a hydroquinone at home, send me the picture. I just want to make sure it's not expired, and it's OK. And if you want to use that one, use that one. But you can't expect outcomes if you're using the wrong topicals. And unfortunately, it's so misleading. But the patients are not educated. What is, I know a lot of people have this question. What is the number one thing you recommend in your office for melasma? And the number one thing you treat patients at home with for melasma? OK. Or hyperpigmentation. Yes, because we are really, really good with melasma. We put patients on an annual plan. That's how we're different than every other clinic. OK. Tell us about that. Yep. There's an annual plan for melasma. We basically map out your year with you. We're like, what are your vacation months? Where are you going to be in the sun? Where do you live? And then we can do a baseline protocol. Some months, they're on a hyperpigmentation cream. Some months, they're on oral trinoxemic acid. Some months, they're on a micro needle trinoxemic acid. And there's a whole, because melasma is forever. Yeah. So what is the formulation and how are we controlling those melanocytes? What acids are we using? What percentage is? That's the trick of it. Because I came back from the summer and I had melasma. And my nose that I'd never had before in a little bit on my cheeks. And I came to see you and your micro needle dead with the acid. And it went away. Well, it's still there a little bit, but it got a lot better. Well, we only did one. And what did I teach you about my greening? We're going to do it regularly once a month, all the time. We do this afternoon again. We're going to do it today. Yeah. So that was amazing. And I was like, wow. And then I sent one of my best friends to you, because she had a baby. And she's melasma on her cheeks. And I was like, wow, the results I saw from this were insane. And let's talk about your best friend who had thousands of dollars worth of amazing moisturizers and nothing at home to work with pigment when I told her to send me a picture. And I feel bad. I feel so bad for my patients, because they're spending all this money. And they're not getting results. And I'm like, the protocol is not properly put together. Because I need to be working every single day, especially as we get older. I mean, we live in Miami to things that help even out your skin tone. Always, always, always. Yeah. And those things, just like anything, just like peptides, they're cycled. Yeah, of course. So sometimes the hydroquinone, sometimes it's trying to see make. Sometimes it's cold. It's cold. Sometimes it's a nice cinema, prescriptions. But we're always changing. But what stays the same is protecting the melanocyte. And you have to have these ingredients that kind of put a coat on the melanocyte. So you can't hyperpigmit. And when patients are just coming home with peptides and stem cells that are 12, you know, 1,000, 200 dollars from another dermatologist, those are great. They're fine. They're great additives. But you're not working on pigment. Correct. So now we need to have a poll on you. Yeah. All right, sucks. I have to buy a whole bunch of skin care. But I'm like, this is how we get it done. Yeah. And listen, like if you want to get it right, you got to put together the right protocol, whether the inside, external, all of those things. What about, what is it that they're typically this way? Stop being scared of injections and start some peptides. Because they are a game changer. They're the future game changer. So I'm also really passionate about peptides and skin care in the right and dose. There are a lot of brands that will bullshit you. And I'm like, oh, yeah, peptides and skin care, the dose is not even high enough. Two brands, I personally think a little bit more commercial, but they're doing it well. And I've been using them for years. And I really like them. One is, what is that one called? Is that alai? No. Something alai. Ryan, what's the one that I, one skin? Someone that I love, one skin has a lot of my research. A lot of my research. They always want peptide. They're before and after. They're clinically research studies. They're showing their research and data all the time. I think it might have also gone acquired recently. But they're really good. OK, one skin? Call me because I didn't know they had clinical studies. Yes, fully back with clinical studies. And they're doing their own clinical studies all the time. Their body lotion is amazing. I'm like, I really love it. And they have this OS-1 serum that I love. Using it for two years, I cream for two years, love it. The other brand that I like, which more of this, one of these biohacking brands, but their retinol is incredible. It doesn't make you peel. It's called Young Goose. OK. Again, a lot of peptides, NAD, their vitamin C is incredible. And their retinol is like nothing I've ever experienced because it does not make you peel. It's probably double bonded. Yes. And it's gentle. And you can use it five, six days a week. And it's amazing. And so these brands are something that are maybe a little bit more commercial, but aren't doing it well. And I've seen great results from them. And I think that that's great that you shared those brands because not everyone can afford or some people aren't Idaho where they don't have a cold-hipped dermatologist. They're not in Miami. And they'll be able to like, easily access these things that are not prescription online. And they still work. And you can, they have an Amazon storefront. Make sure you guys do not just buy from Amazon. Make sure the brand has a storefront or you might be getting scammed. Right. And then you can also just get it on their websites and they ship all over the country. And so I was like, these are two great brands. I like them. I use them. Another brand that I really like that's easy and clean. It has great hydration products. And stuff is agent nature. Jenna's great. I like some of her products. But these are accessible to people. And they're not necessarily medical office rated, but they've been great for my skin. And I do have hyperpigmentation. And let's thank God for science. Correct. Every time a patient comes in my office and they're like holding this tube of Trent Noyan, I start shaking. I'm like, OK, are you peeling? Are you? I mean, it works for some people's skin, for sure. But I'm like, have you ever heard of a double bonded retinal that you might not freaking peel with? Because I hate the peeling. It takes the... I'm on camera so much. I don't have time to peel. No, I don't. Right up here. Yeah. Alpharet from Skinbetter flies off my shelf. I can't keep my stock. Which one is it? Alpharet. And it is their double bonded molecule. But it just takes the retinal deeper. So you're not doing the cellular turnover. Like, everyone doesn't need to look like an ugly duckling anymore. Like, let's use science to our advantage. Everyone should be on a double bonded retinal. MJ, I just adore you. I'm so glad Liz introduced us. And guys, you need to go look at Liz Kennedy's face. She's one of the most beautiful humans. And not because she's a close friend, she's just gorgeous. And magnetic. And magnetic, yeah. She's just a great person. And her skin is incredible. And she swears. She's like, MJ is responsible for my face. And believe me, Liz, let's incredible. And so I'm so glad we became friends. And I love educating my audience on beauty. I'm no gatekeeper. I'm so open about the treatments that I do. I was like, we should all age how we want to age and look great while doing and support each other. So thank you for coming on the show. No, thank you. Thank you for letting me talk about regenerative aesthetics. I hope that the future of everyone's face, it has to be. It's not fillers. It's repair, regrowth, and regeneration. And you know what's beautiful is even plastic surgeons where I love and adore are starting to do hyperburet oxygen treatments. Rod light therapy, when they're doing fat transfer is like, Miguel Mascarras totally integrated the stuff into his practice. And I think that is the future of medicine. So if you're seeing a surgeon as well, and they do not look at things from a functional lens, then do not be going to that surgeon because your recovery and how the procedure holds up will make a big difference on how you choose to recover. Oh my god, yes. Can I just say one thing on that topic before you close? It's insane. The amount of patients who come in now from a couple of surgeons that we've been working with, it's not about the post. It's about the pre-procedure. Pre-hyperbaric B4. Red light B4, a peptide protocol B4. You need to prepare this cell. There's a higher replacement therapy before. Yes. Prepare the cell to be optimal prior to injury. They're better outcomes. You're down times in half. In half. When I did my episode, I brought Miguel on twice as a guest because my audience is loved him. Miguel said his women who come in for facelifts in their 40s and 50s, who are on-hermer replacement therapy versus not the results are like night and day. He's like the women who are on-hermer replacement therapy have much better results than outcomes and the procedure like the facelift, neck lift, whatever it is will last so much longer than women who are not. Well that's interesting because my take and the reason we do pre-impose, right? Peptides red light is for healing. Yeah. But to know that the results can actually last longer, like where's the test? I'm starting now. I'm preparing for my face. That's what you do. And for example, when I did my fat transfer with him in February, I was on recovery peptides. He made me do red light therapy. He made me do hyperbaric oxygen. He was so consistent with me about that stuff. He made me run all my peptides through him. And so I had a better outcome and the fat actually stuck versus when you do a fat transfer, you can lose a lot of fat. But my fat actually stuck on. And even now a text of me is like be quiet. Give it a year. And I'm like fine. You're like the regenerative patient, aren't you? I don't see it yet. I'm like you were here yesterday. Yeah. I'm sick. Can you give me a little time? I just want to be plum. You are plum. You're plum. You're beautiful. That's it. That's what I want. Thank you, my love for coming on the show. And I'm so excited to teach my audience about ways to age gracefully and empower you women and make you feel and live your best self. Thank you for tuning in to Biohacket. If you've enjoyed today's episode, please don't forget to subscribe, rate, and leave a short review. It really helps us reach more listeners just like you. Follow us on Instagram at biohack.it for inclusive content and the latest updates. Remember, your health is in your hand and curiosity heals.