LONGEVITY with Nathalie Niddam

#402: Gut Reset: The SECRET Signals for Longevity Revealed | How to Heal Your Microbiome, Banish Bloating, and Build Resilience With Nat Niddam

63 min
Jan 9, 20265 months ago
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Summary

Host Natalie Niddam presents a foundational guide to gut health, emphasizing that wellness starts in the gut. The episode covers digestive optimization, microbiome diversity, gut barrier integrity, and the four Rs of gut healing (remove, replace/restore, re-inoculate/replenish, repair), along with practical lifestyle modifications and supplement strategies.

Insights
  • Gut health is foundational to longevity and all advanced health interventions; without it, other strategies have limited efficacy
  • Most people normalize chronic bloating, gas, and digestive issues as normal rather than recognizing them as signs of imbalance requiring intervention
  • Long-term PPI use (proton pump inhibitors) was designed for 6-8 weeks but is commonly prescribed for years, leading to mineral malabsorption and increased cardiovascular and bone density risks
  • Microbial diversity requires testing before supplementation; too little or too much of specific bacteria like Akkermansia can be problematic
  • Meal timing, eating state (parasympathetic vs sympathetic), and chewing thoroughly are as critical as food quality for digestive health
Trends
Shift from symptom suppression (PPIs) to root cause analysis and functional restoration of digestive capacityGrowing consumer interest in microbiome testing and personalized probiotic selection rather than generic supplementationIntegration of traditional medicine practices (Ayurvedic bitters, bone broth, fermented foods) into modern functional nutrition protocolsBioregulator peptides emerging as adjunct therapy for organ-specific rejuvenation in digestive health optimizationEmphasis on circadian rhythm alignment for meal timing as a longevity and metabolic health strategyRecognition that overtraining and chronic stress are gut-damaging factors comparable to poor dietIncreased practitioner focus on comprehensive gut assessment (digestion, barrier integrity, motility, microbiome) rather than isolated interventions
Topics
Gut microbiome testing and diversity assessmentDigestive enzyme supplementation and HCL supportGut barrier integrity and leaky gut preventionCircadian rhythm meal timing and intermittent fasting protocolsProbiotic and prebiotic selection strategiesProton pump inhibitor (PPI) long-term use risksStress management and parasympathetic activation for digestionElimination diet protocols and food sensitivity identificationBone broth and collagen peptides for gut lining repairFiber intake optimization and gradual increase strategiesGallbladder health and bile production supportLiver detoxification pathways and supportBioregulator peptides for organ rejuvenationFermented foods and traditional probiotic sourcesGut motility assessment and constipation management
Companies
Wizard Sciences
Manufactures TrankDart, a multi-pathway sleep support supplement featuring glycine, GABA, and other sleep-supporting ...
Level Up Health
Produces Complete Liver Complex for liver detoxification support and Ultimate GI Repair peptide formula for gut healing
Vitale
Skincare brand using copper peptides (GHKCU) and exosomes for cellular signaling and regenerative skin support
Vitrack
Gut microbiome testing company providing comprehensive analysis of microbial diversity; requires practitioner ordering
Just Thrive Health
Produces spore-based probiotics in gummy and capsule forms, plus digestive bitters formula for pre-meal digestive sti...
Seed
Manufactures a foundational probiotic formulation recommended as baseline gut health support
Bioptimizers
Produces Mass Enzymes (full-spectrum digestive enzymes), HCL supplements, Probiotic Breakthrough, and Gut Breakthroug...
People
Liz Parrish
Gene therapy expert previously interviewed on the podcast discussing advanced longevity interventions
Dr. Cynthia Keller
Physician expert on gut health with upcoming podcast episode (February/March 2026) discussing functional medicine app...
Grace Lu
Functional medicine practitioner referred to as 'the gut goddess' for expertise in microbiome assessment and gut health
Quotes
"Disease and or wellness starts and ends in the gut. There's so many disciplines that speak to this. Traditional Chinese medicine speaks to the gut. Ayurvedic medicine goes to the gut. Everything starts in the gut."
Natalie Niddam~8:00
"The gut is where the outside world meets the inside world, you being the inside world, the outside world being everything that enters into your GI tract from your mouth."
Natalie Niddam~8:30
"When we try something and it doesn't work, the tendency is to get disappointed and say it didn't work. But here's the thing, everything that doesn't work becomes a piece of information."
Natalie Niddam~15:00
"PPIs were developed to be used for six to eight weeks at a time to allow the stomach to heal. They were never intended to be used on the long term."
Natalie Niddam~35:00
"Digestion starts actually when you start thinking about the meal. You can feel the salivary glands starting to work when you're looking at your food and thinking about it."
Natalie Niddam~45:00
Full Transcript
Welcome to Longevity. I'm your host, Natalie Knidham. I'm a nutritionist, a human potential and epigenetic coach, and I created this podcast to bring you the latest ways to take control of your health and longevity. We cover it all, from new technology and ancestral health practices to personalized interventions and a very special interest of mine, peptides and bioregulators. Enjoy the show. Have you ever noticed how your body says, I'm tired? But your brain's like, let's lay here and over analyze everything you've ever said to anyone. You do everything right, dim the lights, no screens, chamomile tea, but your brain is still wired. And this is where TrankDart comes in. A multi pathway sleep support from wizard sciences. This is not a knockout pill. It's a gentle nudge toward that wind down zone. I take it about 30 minutes before bed. And it actually helps my body and my brain sync up for sleep. It's layered support, glycine to help cool your body temperature, GABA to press the brain's brake pedal, the laryon root for that herbal calm and five HTTP to help serotonin flow into melatonin. Even your gut gets some love with inulin and blue spirulina. If your brain's been ignoring bedtime lately, check out TrankDart at wizard sciences.com and use code NAT15 for 15% off. I've been using it for a few nights and I am loving it. January makes you want to detox, but not hate your life. Listen up. Most people think detox means suffering. But the truth is your body already knows how to detox. All it needs is the support. When your liver is overloaded from alcohol, from sugar, from inflammatory foods, it stays stuck in survival mode instead of performance mode. This is where complete liver complex by level up health comes in. January is a great month to introduce this supplement so that you can support your liver's natural detox pathways. No fasting marathons, no weird teas, and no white knuckling. This formula supports hormone clearance, blood sugar regulation, cholesterol metabolism, and fat processing. All the things that tend to get a little you know, kind of stuck after the holidays. And a supported liver means better energy, clearer skin in a body that feels ready for what's next. January isn't about pushing harder. It's about clearing what's holding you back. I love this liver complex, you guys. I do 30 days every few months every year and it never fails to deliver. So to get your hands on your own, go to leveluphealth.com, LVLUpHealth.com, and make sure to use code NAT to save 20% off your order. Hey, folks, as we kick off 2026, I thought that it might be helpful for all of us to kind of move back into, back to kind of basics. When it comes to, you know, we talk about longevity, we've talked about so many advanced concepts, right? We've talked about gene therapy with Liz Parrish. We've talked about exosomes and stem cells and advanced tech and so many fascinating, fascinating strategies that are out there. There's some incredible supplements to support our longevity. But at the end of the day, it always comes back to foundations, right? It always comes back to the things that we do every single day, those basic lifestyle habits that fundamentally support our ability to then do the more advanced things. And one of the most foundational things of the foundations, so the foundation of the foundations of the foundation, I believe, lives in our gut. It is said that disease and or wellness starts and ends in the gut. There's so many disciplines that speak to this. Traditional Chinese medicine speaks to the gut. Ayurvedic medicine goes to the gut. Everything starts in the gut. And there's a good reason for that. The gut is where the outside world meets the inside world, you being the inside world, the outside world being everything that enters into your GI tract from your mouth. That tube that starts in the mouth, goes down your throat, becomes the stomach, the small intestine, the large intestine and finally evacuates through the rectum. That everything that lives inside that tube, that is we refer to as your GI tract, is fundamentally to your body, the outside world. And our ability to manage that interface is what is critically important to our health in every single way. We have so much of our immune system lives in our gut for that reason, because it is in the gut that the body has to decide what belongs here and what do I need to reject. This is where the immune system's first job is, is determining what is friend and what is foe. And we have this massive community of common cell bacteria and pathogens, all of the gut bugs, the trillions of gut bugs that help us to manage our health. This is a symbiotic relationship. They are not us, they outnumber us. And yet they are critically important to our well-being. Not only do we have to coexist with them, but we rely on them to generate for us a lot of the nutrients, things like short chain fatty acids or certain vitamins that we need to be well. So for this reason, I wanted to dedicate this first episode of the year to gut health, because without our gut health, we got nothing. So, yeah, I'm going to try to keep this as useful as possible for you guys. This is not intended to be a master class, although, you know, it might be a good place to orient yourself. And nor is it intended to be a DIY fix your gut kind of podcast, but it is intended to get you thinking about some of these different things to really think about, is this something that you need to focus on? Do you need to go out and find a practitioner to work with who can support you in this journey if it comes to pass, that you decide that things are out of balance? And I cannot stress to you enough the importance if you have an imbalance in your gut of finding that practitioner who is going to walk with you and help to guide you. There are so many different tools out there to fix our guts. The biggest nut to crack here is understanding where is the imbalance and where to begin. So I'm hoping that with some of the things that I'm going to talk about in this episode, it's going to give you a chance to maybe knock down some of the low hanging fruit so that when you do find that practitioner or decide to go to the practitioner, you will have done some of the most foundational things at either restoring balance to the gut, or if you try a few things and it doesn't work for you, this is also information. And this is something I do want to lean into. I just interviewed an amazing doctor. Her name is Dr. Cynthia Keller just the other day. That episode, it'll come out, I believe around February, maybe beginning of March, is she is a gem. And one of the things, one of the concepts that she kind of brought back to the forefront for me is that, you know, when we try something and it doesn't work, the tendency is to get, you know, to be disappointed and I didn't work. But here's the thing, everything that doesn't work becomes a piece of information. It becomes a data point towards the step of understanding what can work or what might work or what is actually out of balance. So when you try things and they don't land for you, and this happens a lot in figuring out gut health, because gut health is complicated and it, you know, it can be many, many different things. So by no means am I trying to drill everything down into a simple, oh, well, it must be this kind of podcast, rather, it's really to say, we have to start somewhere and every data point along the way is valuable, whether it's something that worked or something that didn't work. So when you're sitting with a practitioner and you're going through with them, trying to help them to understand you and learn you and get insight into what's happening with you, please don't leave out the things that didn't work. Because sometimes that is a bigger hint to them than the things that do work. All right, plus it knocks out a bunch of stuff that you don't already have to do. Now, here's, here's some of the signs that your gut might be out of balance. Things like gas, bloating, pain, reflux. So that means when you get heartburn. So right, so there's burping can be a sign of imbalance, constipation, diarrhea, like those are the obvious ones. But the gas and the bloating is something that I want to bring your attention to because and actually even constipation and diarrhea, because here's the thing, the way that we get through our day, the way that we get to show up every day is that we adapt, right? We, as humans, we are so good at adapting. And even those of us who like to complain the most, at the end of the day, you're dealing with a lot of stuff. And what we do to get through it is we normalize. And normalization of bloating, gas, even reflux to a degree or burping and constipation or diarrhea or alternating between the two, until it gets really, really bad that we can't function, we will normalize. So if you get to the end of the day and your pants are tighter than they were at the beginning of the day, if you really think about, am I bloated and gassy often? I want you to sit back and think about that and maybe think about it through the day. Because I remember when I used to work with clients as a holistic nutritionist, and I'm starting to kind of pine for those days. So I may have to go back to that someday. But I will tell you that one of the things that was so remarkable is when we would sometimes change a person's diet or clean things up, one of the things they would come back and marvel at, and sometimes within a week was, oh my gosh, Matt, I had no idea how bloated I was feeling. I had no idea how tired I was or how uneasy I felt all the time. Sometimes we've normalized how we feel to the point where it's just the way we are. And we think that that's the way it needs to be, but it doesn't. So the gas, the bloating, the acid reflux, burping, acid reflux and burping are related, but they're not the same. Constipation, like kind of forget last time we went to the bathroom, that's just the way we are. We've always been that way. Or the loose stools. All of these things are signs that the gut is not doing. It's not well. Other signs can be things like fatigue, brain fog, things like getting sick very often or getting, you're that person that gets that stomach flu every time it goes around. That should not be the thing, right? That your gut is your defense system. So if things are constantly making you sick, then something in there is not working well. These are the signs and symptoms you want to look out for. Next, what are the things that are constantly, that are stressing our gut? Why is this such a problem? Well, we've been talking about this a lot lately. The last solo episode I did was 10 ways to manage your stress. Chronic stress is absolutely one of the things that absolutely will challenge your gut. And it will damage your gut because mechanistically, when you're chronically stressed, you shut down your digestion. We're going to talk about digestion in a minute. If you're not digesting your food properly, that in and of itself is damaging to the gut. That in and of itself is going to drive constipation and it will drive damage to the gut lining. So chronic stress, plus it keeps your cortisol levels high all the time. Excessively high cortisol levels that are high too often is going to be bad, obviously for your blood sugar. It's bad for your brain, but also that excess cortisol that is always high that never comes down is a catabolic steroid. It's a steroid that breaks things down. When you're stressed, you can't be digesting, you can't be building. So being in a chronic state of stress is ultimately a damaging thing for our gut health. In addition, poor food choices. Now, I'm not here to lecture you, but I will say, and we're coming off the holidays here. And many of us, we went into the holidays with really great eating habits. And then the things start coming into the house or you're going to parties, whatever it is, we start to slide in our habits. That is another piece of the puzzle when it comes to poor gut health, over processed foods, excess sugar, fried foods, foods that are just like packaged foods, all of these things, not only do they make us look bad because we end up getting weight from them, but more importantly, they are damaging to the gut. So this is your reminder. If you haven't already done it, a lot of people will start January, we'll turn over a new leaf and do every start doing everything the right way again. But if you've allowed the holidays to kind of leech into January a little bit, or it's a slippery slope you haven't found your way back from, this is your reminder. This is the time to reset your nutrition and get back to your beautiful eating habits. And it doesn't have to be complicated, folks. It needs to be whole foods. It needs to be as clean as you can get them. If they're not perfect, that's okay. Don't make yourself crazy. I am a really big fan of a Mediterranean style diet. It'll be different for many people just because different people's different food tolerances or whatnot. But what we're doing is broad strokes, right? And then you may have particular circumstances that changes for you. But broad strokes for most people, we're going to be eating clean protein. We're going to be eating healthy fats. And healthy fats in my world means we're looking at things like polyphenol rich, extra virgin olive oil. We might for our saturated fats, we might have some ghee, we might eat some butter, we may get some saturated fat from our healthy proteins. How much saturated fat that is a completely particular, personal, if you will, scenario because we have different needs, different stages, different ethnic backgrounds. All I'm saying is whatever fat you're eating, make sure that it is the best quality that you can afford. On the vegetables front, I'm a big fan of vegetables. I think that raw veggies can be very challenging to a lot of people, particularly in the wintertime. That's not what most of us want to be eating. So vegetables at the very least steamed is going to be easier for people to digest. And it's going to preserve a lot of those nutrients and give you access to the polyphenols and the fibers and all the nutrients that we know our vegetables are good for. And by the way, when you pair them with that healthy fat, it allows you to be able to absorb some of the nutrients even more easily. So what have we got? We've got our healthy protein, we've got our healthy fats, we've got our vegetables, we're going to prioritize for most of us, we're going to prioritize the vegetables that grow above ground, because the ones that go below ground are starch here and more dense. You can eat some, but again, this is going to rely on your state of health, on your activity levels. But again, we're still going to eat all of them. Now what about eggs? Eggs are great if you tolerate them. Dairy. Dairy is fantastic if you tolerate it. Do an experiment for me. If you find that you're bloated, cut out dairy for a week, see if your bloating goes away. I just did it the other day and you know what? I stopped putting milk in my coffee, which I don't, I didn't used to put milk in my coffee. I knew that milk made me bloated. And then you know, yeah, I had a latte and I was like, oh my God, this is so good. And so then I had another one and another one. I was like, oh yeah, I'm fine. I'm doing fine. And then the next thing you know, I'm walking around like a balloon and I'm like, what is going on? And it took me a little while to kind of say, oh right, yeah, I'm back at dairy and I took away the milk and guess what? The bloating went down. It was that simple. Can I tolerate yogurt? Yeah, a little bit of yogurt I can tolerate. Everybody's going to be a bit different. Okay, so I'm not making blanket statements here, but I am saying the most common offenders in those food choices, even healthy food choices, are going to be things like eggs, grains, wheat, dairy. These are the ones and if you suffer from bloating and you have an addiction to eating raw cruciferous vegetables, things like broccoli and cauliflower, I'm telling you now, start cooking them. You will find that you will tolerate them better. Raw broccoli and cauliflower is really hard on the gut. They are good foods, but they're better when they're cooked. There's lots of other reasons for that, but I'm don't want to go down too many rabbit holes here. So better food choices. Also, processed meats. A lot of the negative research on meat for human health, if you look at the data very often, what these people are eating is a lot of processed meat. So this is salamis, cold cuts. And frankly, if you look at a lot of the recalls in the world, it has to do with processed meats. So stay away from them, at least while you're working on your gut health. What else? Toxin exposures. So cooking in things like, I don't think anybody listening to this podcast ever does this, but if you still do this, please stop now. Reheating in plastic. Get rid of plastic containers wherever you can. Use glass. Glass is way cleaner. Yes, if you drop it, it will break. It's okay. Better that than doing anything with plastic. So keeping plastic away from your food, keeping tin foil away from your food. I am still amazed that people still wrap their food in tin foil to cook it. No, don't do it. The aluminum is really bad for your brain. And it's really bad for your gut. So if you're going to use aluminum to cook something, line it with parchment paper. Okay? First parchment, then the aluminum, your food goes on the parchment paper if you're even going to go there. Things like nutrient depletions are really bad for our gut as well when we can become deficient in zinc, for example. Zinc is a very important element for us to produce digestive enzymes. So nutrient depletion obviously is going to be a negative. It's going to be a factor. Lifestyle factors, like I said before, stress, things like exercising. Now, we need enough exercise to be healthy and to have a healthy gut, but those of you who are obsessed, those of you who are maybe training for a high rocks competition or a marathon, be careful. Overtraining will challenge your gut health, badly. And actually, even your immune health. So overtraining is a massive issue. If you don't exercise at all, that is also a problem. So get out and go walk it. But if you are one of those people that overtrains, know that there are consequences to the gut. Dehydration, we don't talk about dehydration nearly enough. Being dehydrated is a factor for gut health. It's a factor for your whole body, really. But one of the things that your body can't make when you're very dehydrated, and by the way, if you're also deficient in zinc, is digestive enzymes. And if you're not making digestive enzymes, you're not breaking down your food properly. And if you're not breaking down your food properly, it's just sitting in your stomach and it's fermenting and it's causing heartburn. And then your doctor gives you a PPI, which is a proton pump inhibitor, because he says, well, you have too much acidity. But sometimes it's because you don't have enough digestive enzymes. And if you don't have enough digestive enzymes and that food is sitting there and fermenting, and then you get a PPI, and you're on that PPI forever, which I see a lot, there are consequences to that. Because what is the proton pump inhibitor doing? It is stopping your stomach from producing hydrochloric acid, which is what your body produces naturally to break down food. Well, guess what? If you're not producing hydrochloric acid, you can't process your minerals properly, things like calcium and magnesium. And now you're not absorbing them properly. And there's been studies that have shown that people who are on long term PPIs, this is long term use, not six to eight weeks, which is what they were originally intended for. People who use PPIs for years have a higher incidence of cardiovascular disease, of heart attacks, and of bone density issues. Because it's because of those minerals, it's because the calcium and the magnesium, because they're not being chelated, they're not being absorbed properly, they can't be used by the body properly. And now this takes a toll on the lining of your blood vessels and on your bones. I think we can all agree that these are massive hits to our longevity. So PPIs, I'm not a medical doctor, and I don't know every one of you. So if you've been prescribed PPIs, just know this, they were developed to be used for six to eight weeks at a time to allow the stomach to heal, to allow for a change in circumstances so that you wouldn't need them anymore. They were never intended to be used on the long term. Now, if you are listening to this podcast, and you've been on a PPI for, fill in the blank, a year, two years, five years, 10 years, really consider the fact that it would be a good idea to work with a practitioner to get yourself off the PPI so that your body can start producing stomach acid the right way and digesting your food properly. Again, this podcast is not meant to solve all the problems. It is meant to bring attention to certain issues and then help you to point you in a direction where you can go get help to get it solved. Okay, what's next? We've talked about the signs and symptoms that your gut may need attention. Now, what are the elements of a good, healthy gut? Right? What are the elements that we're looking for? We're looking for healthy digestion. We just talked about PPI's. We want to be able to break down our food properly on our own. And what this means, ideally on our own, but as we age, that may not be possible. Now, what does this mean? It is said in the land of nutritionists where I was first trained that your body needs to be able to break down food in the gut so that it can absorb it and it can then assimilate the nutrients. You can be eating the best diet on the planet. If your digestion is not good, if you're not breaking that food down properly, you're not going to be able to absorb it and your body won't be able to assimilate it. And that means you could be spending all this money on great food and still be nutritionally deficient. That would suck, right? So we want to have proper digestion and that requires us to be making enough digestive enzymes, releasing those pancreatic enzymes. We want our liver to be processing food properly. We want our gallbladder. If we're lucky enough to still have a gallbladder, we want it to be releasing bile when it senses the presence of fat so that we can emulsify those fats and we can move things through the digestive tract properly. So proper digestion is key and I'm going to talk a little later about how do we maybe address digestion that goes sideways. So when does our digestion get challenged? Well, it gets challenged when, got that thing, that first thing that I said, stress. When we are stressed, when we sit down to eat, we will not digest our foods properly. How is that possible? Well, it's a survival mechanism. If your body thinks you're under threat, digestion is the last thing it thinks you need. And this is where living in a constant elevated sense of doom or stress is going to compromise our ability to have good digestion and to have good gut health. So what can we do about that? I'm going to, I want to give you a couple of solutions as we go along here. One of the things, one of the practices that comes from us from traditional people who are more traditional, and I'm not going to say that you have to say a prayer every time you eat, but if it aligns with you, if this resonates for you, that might be the thing that you need to start doing. And it could be, it could be 20 seconds. It could be just closing your eyes, smelling the food, being with the food, expressing gratitude for this food. That alone can be enough to get you out of the rush, rush, of your day and into a state of rest and digest. What we want to do is flip out of a sympathetic state and flip into a parasympathetic state that's rest and digest when we're sitting to eat our meals. It can look like a prayer. It can look like a blessing. It can look like four deep breaths. It doesn't have to have anything to do with prayer or anything at all. It could just be sitting in front of that food, putting your phone away, putting your computer away, and trust me, these are traps that I fall into as well. We're like, oh, this is great. I'm going to just sit down. I'm going to read my, I'm going to scroll on my phone. Bad idea. That's called doom scrolling, or reading your emails. You're going to read that email that's going to send you to the moon, or whatever, or hopefully you're sitting with someone whose company you enjoy. Take a moment, stop, breathe, relax, take a sip of water. We'll talk about some of the supplements that we might take to help our digestion if we need it a little bit further. But if you don't want to use supplements, then this might be the time if you want to have something like, something bitter, something bitter to start the meal. And this is a practice out of Ayurvedic medicine. And it's also a practice out of a lot of traditional diets. Like if you look the way the Italians eat, they'll have like a bowl of bitter greens, like arugula with some olive oil, salt, maybe a little bit of lemon. That is a strategy not only is it tasty, but it's actually a strategy to get your digestive juices going. In Ayurvedic class in school, my professor used to talk about having a bolus of ginger or a little shot of ginger before you eat your meal. But definitely having something bitter or something to start those digestive juices going might be a really great way to start a meal. But before you did that, remember, you sit, you breathe, you come into presence, you look at your food, you smell your food, you prepare your body to receive the food digestion starts actually when you start thinking about the meal, you can feel the salivary glands starting to work when you're looking at your food and thinking about it. Alright, so first thing we've calmed ourselves down. We've maybe started with something to get our digestion going. If you have blood sugar issues, you might start before your meal with a little bit of apple cider vinegar and water. If that resonates for you, that'll help to mitigate blunt the blood sugar later on. And you may be sitting there going, well, what's this got to do with digestive health? Everything. Okay, if we don't have good digestion, we are not going to have good gut health. So digestion is key. Now, what's the next step? There's a third step here that many people don't even think about anymore. But I think is something that we really all need to think about even once in a while. It's chewing your food. I'm not going to sit here and tell you to count how many choose, but I am going to say that for many of us, because we're rushed because we're always moving fast and especially if we're distracted, we often are not chewing our food well enough to break it down properly. And if it is not properly broken down and chewed, you're going to have a much harder time digesting it and extracting the nutrients out of it that your body needs. So chewing your food thoroughly is a major, major piece of the puzzle. Now, the last thing I want to bring to your attention is drinking while you're eating. And by drinking, I mean anything. I mean water, pot, like anything, not that any of you are drinking pop, maybe some of you are, but any kind of, if you drink a lot of fluids during your meal, you are essentially diluting your digestive juices. I'm personally a huge fan of hydrating in between meals, maybe having a little something to drink after my meal. And I'm not talking about alcohol here, nor is this going to be a lecture about alcohol. I don't think alcohol is our friend when it comes to digestive health. It's not our friend when it comes to longevity. It's not our friend, period. But even drinking a lot of water while you're eating is going to number one, cause you to bloat. And number two, it's going to compromise your digestion because all that water is doing is diluting the digestive juices that your stomach is producing or maybe that you're taking as a supplement. So if you're a big drinker during the meal, cut it out. Avoid drinking a lot of fluid during your meal. You might want to take a little sip of water here and there, a little sip of something here and there, but try to avoid the big volumes of like a fluid. Okay, let's face it, you can't change your biology, but you can support it intelligently. A lot of products chase surface level results while ignoring what actually drives resilience underneath, communication. When signaling gets distorted by age, stress or environment, repair becomes less coordinated. And this is important, and especially in skincare. Vitale understands this. They first earned my trust years ago with pharmaceutical grade copper peptides like GHKCU, one of the most researched regenerative signaling molecules that we can get access to that actually naturally exists in your body. Now, Vitale evolved that science by introducing exosomes, the body's native messengers. They use zero age exosomes, which means the signals driving repair are cleaner and more efficient. Paired with copper peptides, it's less about forcing change and more about supporting skin to do what it already knows how to do. If you think about longevity in terms of mitochondria, signaling and long term resilience, Vitale is skincare built for your biology. All you have to do to get your hands on some is visit vitale skincare.com and use code NAC20 for 20% off. Now, what's another element of gut health? The integrity of your gut barrier. And this is what we're trying to protect here. You've probably heard that the gut lining is one cell thick. It's super thin. Now, the good news is that renews itself really fast all the time. Every 30 days, it's turned over. But the bad news is that it's also really easy to damage. And so damaging the gut barrier is one of the challenges of all of the things that we've talked about until now, right? Whether it's eating the wrong foods, chronic stress, not chewing our food, not digesting our food, all of these things can compromise and be a challenge to the integrity of the gut lining. And the integrity of that gut lining has everything to do with making sure that the right things get in and that the wrong things stay out. All right. So that's all I'm going to say on gut barrier integrity. We want to keep it solid. And all of the things that we're talking about is what is going to support that gut barrier integrity. Now, proper liver and gallbladder health. Proper liver and gallbladder health is integral to gut health. Why? Especially the gallbladder, because the gallbladder is who is responsible for releasing bile when it detects that we're having high fat. What if you don't have a gallbladder anymore? Sadly, the gallbladder is very often treated as a spare organ by a lot of medical professionals. I was very fortunate early in the game that I was sent to a gut surgeon, a GI surgeon, because I was discovered to have a large gallstone. And I didn't know anything at the time. If he would have told me that I needed to have my gallbladder out at that time, I might have agreed. The good news is I came across a guy who looked at me and said, you know what, there are millions of people out there that take their gallstones with them to their grave. I would wish to you that you are that person or maybe that you figure out how to shrink it, which is a different story. But the good news is he advised me to keep my gallbladder and to just modify my diet. So I've done an episode on gallbladder health. I think it was last year. You may want to go check it out. But suffice to say, if you still have your gallbladder, you want to keep that gallbladder. If you no longer have a gallbladder, it sucks. But things can be managed, right? You may find that you don't really tolerate fatty meals. You may want to take ox bile as a supplement with fatty meals, which will help you to break down the fatty foods and it'll kind of replace your own bile acids. So if you don't have a gallbladder, you're going to want to mitigate for that. But we want to make sure that we maintain because they're all part of the team here, we want a healthy liver and a healthy gallbladder so that all everything works towards better gut health. Alright, what's another hallmark of a healthy gut? Microbial diversity. So this is your gut microbiome. Now, we are not going to solve all the problems of the gut microbiome here. But I will say this, if you've never had your microbiome tested and you have any kind of gut issues, take this as your invitation to find a practitioner and do a good gut microbiome test. There are some really good tests out there. One of my favorites is a company called Vitrack. Now Vitrack doesn't sell direct to consumer. So you're going to need to find yourself a practitioner who does use Vitrack and will use it to understand what is going on in your gut. But getting that view before you go willy nilly buying probiotics and prebiotics and all the things is going to be a major piece of the puzzle for your gut health. And it will affect the all of the pieces we've talked about. Having a healthy microbiome is going to affect our digestion. It's going to affect our ability to maintain a healthy gut barrier. So it is worth the investment in time and money to get that microbial diversity established and measured with a good gut test. So I mentioned Vitrack because I think these guys, first of all, they're very, it's a very well priced test. And it's very accurate. It's a fantastic view of the gut. There are others out there. There's the GI map. There's, there's so many gut tests. So the first step is to find someone who you trust. There's a few really great practitioners out there. There's Grace Lu, who is the gut goddess. She literally is the gut goddess. She's amazing. I've interviewed a number of practitioners on this podcast. Any good functional medicine practitioner at this point is assessing gut microbial health as a part of taking care of the whole human. So maybe we'll do a whole episode on the gut microbiome. But I would say that whatever you do, before you go buying a whole bunch of probiotics, even though I think there's some foundational ones out there that are pretty good, make sure that you get a gut microbiome test, especially if you know you've got some kind of imbalances. Some of the foundational probiotics on the market that you might want to think about trying out and see how you feel. There's a category of probiotics called spore biotics. There's a company called Thrive, Just Thrive Health. Those guys make a great foundational probiotic that is a spore biotic that I think is worth anybody trying out. I also like it because they make it in a gummy form. And you guys know I love a good gummy and it tastes amazing. If you don't want a gummy, it's okay. They make it in capsules too. If that makes you feel more grown up, fine with me. I me, I like the little gummy. It makes me happy. But they have a great foundational probiotic. The other one that's quite good that I think is also a good baseline probiotic, if you will, is seed. Really, really solid formulation. But beyond those, I think when you start getting into the more sophisticated probiotics, and I just think that it's a really good idea to get a microbiome test to figure out what you are lacking in before you start throwing acrimancia in there, right? Find out if you're low in acrimancia. Do you need it? Here's the dirty little secret about acrimancia that nobody likes to talk about. Too little acrimancia, no good. It actually got microbiomes that have little to no acrimancia are associated with microbiomes that cause people to become fat. Too much acrimancia, nobody likes to talk about this. It munches away at the mucin later. So there's a mucous layer on that gut lining of yours. And that mucous layer needs to be not too thick, not too thin, just right. Well, when we have the right amount of acrimancia, it helps to maintain the appropriate mucin layer of our gut lining. If we don't have, if we have too much acrimancia, well now you have too many of these guys munching away at the mucin and guess what? It can deplete the mucin in and of itself can damage the gut lining. So microbial diversity, very important. We're going to talk about, well, I'm going to talk about now, one of the ways to nurture microbial diversity is through our food and eating a variety of different foods, eating lots and lots of different vegetables. If you're going to eat some fruit and fruits, great in small amounts, make sure to stick to those berries, maybe have some kiwis, eat apple peels. Apple peels are great for acrimancia, by the way. There's, you can eat fruit, but eating fruit as appropriate for your goals and depending on where you're at in your journey, but definitely eating a variety of vegetables like vegetables you've never even heard of is crucial to maintaining good gut diversity because it's all those fibers, all those polyphenols. Now, if you're a low fiber consumer, and this is one of the big challenges that people talk about in gut health, is that most North Americans don't eat enough fiber. This is a topic I just thought of right now as I'm talking to you. So, and it's critical, right? We should be getting 30 to 35 grams of fiber a day. Most of us, if we're lucky, are getting 20. Maybe a lot of people, not even 20. You must get fiber because fiber is what feeds the microbiomes. It's what feeds the gut bugs. It's not about you. It also helps you to feel full. It also helps to keep you regular. Now, if you eat 10 grams of fiber now and you're listening to this and when you're one of those people that says, okay, not said I need fiber, I'm going to go out, I'm going to go to 35 grams of fiber tomorrow, I promise you, you will hate me because you will blow up like a balloon. So, if you're a very low fiber eater now and you want to work towards increasing your fiber, do it very gradually because if you go too hard too fast, you will suffer the consequences with a lot of bloating. Your gut microbiome will be kind of maybe happy, but it will not be equipped to deal with all the extra fiber and you're going to end up super bloated and gassy. One of the ways, one of the strategies actually that I'd like to point you towards is using a food diary, something like a chronometer to track your food for a week. This is one of the most helpful strategies I found when I was practicing as a nutritionist with my clients is getting them to track their food for a week. Everybody was surprised. Some people weren't getting any protein, other people weren't eating any vegetables, other people were shocked at how much sugar they were consuming, like way too much and almost everyone realized, oh my gosh, I thought I ate a lot of fiber, I'm getting nothing in my fiber. Using these food diaries, these food logs is a really, really great way to get an idea of where you're at and giving you guidance on how to get to where you want to go. You're going to say to me, yeah, well, when I take out, it's really hard, eat less takeout, eat simpler foods, eat whole foods and it'll be a lot easier to log. One thing I haven't talked about yet, good gut motility. This is how often you poop is really the bottom line. We want to poop every day. Some people say we should be pooping two to three times a day. You know what? I'm a little moderate on that one. If you're pooping once a day, I think you're doing really, really well. Your poop should not take effort. It also should not fall out of your body like liquid. You want to be in that world where it tells you exactly what texture and what form you're looking for. If you're pooping little hard chunks like a goat, you're constipated. If you're pooping liquid, you have diarrhea. Check out where you are on that scale. That is going to be really great information for any practitioner that you're working with. Any good practitioner is going to ask you for this information. If there's food in your poop, if you can see food in your poop, that means you're not digesting your food properly. You may not be chewing it and you're definitely not digesting it properly. So food, discernible food in the poop is definitely a sign of poor digestion and that you have work to do. Good gut motility is crucial. Interestingly enough, when people start taking digestive enzymes and using things like ox bile and toot gut to support the liver and the gallbladder, we start to see better motility. When I used to get really constipated, if I started to support my gallbladder, my liver, and take digestive enzymes within a day or two, my constipation was almost resolved. So definitely, if you're constipated, you want to think about these things as possibility, possible ways of addressing it in addition to hydration and proper fiber and healthy fats and all the other things. Also, cutting dairy. Dairy can make people constipated. Okay, so let's review. The lifestyle habits that lead to good gut health is exercise. Not too much, not too little. Sleep. Good sleep is going to be important for our gut health. And you know, it's not that... I mean, well, first of all, when you sleep enough and you sleep well, there's time for your body to repair and restore itself, and your gut is part of that repair and restore project. Sleep deprivation is a killer for gut health. It's a killer for everything else. It's definitely a killer for gut health. So fixing your sleep, managing your stress, eating healthy foods, making sure that you're in a parasympathetic state when you're eating, being hydrated, but not during the meal. I know so many rules. I get it. I know, but it's not that complicated. Once you build the habits, it's easy. Hydration. Really important. What you eat, how you eat, and when you eat. And of course, your state when you eat. Now, when you eat is important. That is one thing I haven't talked about yet. And that is respecting your circadian rhythm by meal timing. So for most people, and we're going to talk a little bit about intermittent fasting here, but for many people, intermittent fasting has become a very convenient way for them to manage their lives because it takes breakfast off the table. They don't have to think about eating until 12 o'clock in the afternoon. And it can work for a lot of people. But I will tell you that it's not going to be ideal every day for everybody. For most people, it's not going to be ideal, especially for women. We do better if we eat a good solid protein meal first thing in the morning. Research shows that if we eat a good solid protein meal first thing in the morning, we are less likely to overeat later in the day. And I will also tell you that in a world where we're not hitting our protein goals to begin with, that first protein meal is really important. Because now we've upped the ante, we have less hours to get our protein in. So good good health requires that we eat solid meals at good intervals of time and preferably that we stop eating at least three hours before bed. Why? Because while you're sleeping for starters, your body has other things to do. If you have a full stomach when you go to bed, all that repair and rejuvenation and restoration that's supposed to happen is going to get pushed aside because your body's got a nondial with this food in your stomach while you're trying to sleep. You will notice for those of you who measure your sleep scores, you will notice that your sleep scores will never be great when you've eaten too close to bedtime. So you need to give your digestion a rest. You need to give the digestive system a rest. And the best time to give it a rest is overnight. And even better time, if you're going to skip a meal, it turns out that the best meal to kind of skip or go very light on is dinner. The problem is that socially it's hard to manage, right? So do the best that you can, but no matter what, try to be done with food by 7pm at night by the time the sun sets. Now if you live where I live, that's four o'clock right now. But I'm not gonna, I don't stop eating at four o'clock most days because for my family, we're gonna have a meal around six or seven o'clock at night. But definitely try to finish your last meal around six, seven at night and then don't eat again until the next day when you wake up, let's say seven or eight or nine in the morning. You've, look at that, you've got a beautiful 12, 13 hour window of no food, which gives your digestive tract a beautiful break to do the repair work that it needs to do. And that way you can start fresh the next day. I'm not a big fan of snacking through the day. Some people with hypoglycemia issues may need to do that. That's a whole other podcast unto itself. I typically prefer people to eat three meals and skip the snacks if they can. There are situations where snacking might be indicated. I'm not gonna go there now. I will say that if you're eating balanced meals, you're getting enough calories, you're getting a good balance of protein to healthy fat to those low glycemic carbs, you should be able to make it easily three to four hours between meals. Meal timing check is done. We've already talked about sleep. All right. I want to close with a concept of gut healing that I learned when I was in nutrition school. And we call it the four Rs of gut healing. And many of you may have heard of this before, right? What are the four Rs stand for? And this is a brilliant, brilliant strategy. Somebody just said to me the other day, oh, I have four Rs of healing. It's this magical template. And I'm sitting there going, yeah, but I learned about that in school. I don't think you came up with it. But you know, who knows, everything that's old is new again, sometimes. Here are the four Rs of gut healing. First are is remove. Remove the offenders. Right. So we've talked about what they all are. It could be eating the wrong foods. It could be alcohol. It could be bad lifestyle. It could be excess stress. It could be not chewing your food. It could be eating foods that don't agree with you. So foods that are otherwise healthy, but don't agree with your system. Whatever that is, get it out of your diet. The obvious things that most nutritionists or dietitians or health practitioners will remove from a person's diet when they're not sure what's going on is the first thing we're going to go after is eggs because eggs are very, very allergenic for a lot of people. Wheat, most grains, but not all grains, but definitely wheat, dairy, sometimes nuts. It's a good idea to get rid of nuts at first. And we can always bring them back. And when people are despairing in front of me, I'm like, look, we're just doing this as an experiment. Let's see how you feel. And then we'll reconsider. And of course, alcohol. Alcohol, if you're having gut issues, guys, alcohol's got to go. The other one that sometimes has to go for people and brace yourself, you're not going to like this is caffeine. And especially on an empty stomach, caffeine can be really, really irritating to a gut that is already in trouble. So you may need to cut the caffeine for a period of time, or you may need to make sure that you get something into your stomach before you have your coffee just to buffer it. Okay. So that's removed. The next R, and there's actually two of them, we sort of cheat a little bit, is replace restore. So this is where we want to restore digestive capacity, for example. And so we're may this is where we're, first of all, replacing, we're bringing in a nutrient dense anti inflammatory diet. So I just talked about a lot of the things that we remove. We might also take out nightshades if nightshades, if inflammation's a problem. So nightshades is things like white potatoes, peppers, tomatoes, eggplant, goji berries, all of these, all of these foods can be inflammatory to certain people. And then we're going to restore digestive capacity. And this is where the conversation around digestive enzymes comes in. Digestive enzymes can be incredibly helpful for people. We've got something like HCL, which is a digestive enzyme that we use particularly around protein, like animal protein foods. And then there, and then we have broad spectrum digestive enzymes. I really like mass enzymes by, by optimizers, because it's a full spectrum digestive enzyme, I think it's really good. They have the HCL separate. And just those two products alone taken with your food can be really, really powerful at helping you to break down your food properly. That's the one brand that I use. I really like them. We'll put links and codes to stuff in the show notes. I'm not going to clutter the content here with it. But I really love their stuff. They actually also have, now that I mentioned it, I know that I mentioned seed and just thrive probiotics earlier. Bioptimizers has a really great probiotic, maybe called probiotic breakthrough. It's a really interesting, very intelligently designed probiotic. It might be one of those ones that you might want to try. But I digress. The other way to support digestion, I may have mentioned it earlier, just is having bitters before the meal. That might be too much work for some people. So just Thrive Health actually has a digestive bitters formula that is a pill. It's a one capsule. You pop it 20 minutes before your meal, and it'll stimulate your digestive system to get going and prepare to receive the food. So those are some products that can be really helpful. And that's what we're doing in the replace and restore kind of stage of gut healing. Next, re-inoculate and replenish. Now, this is where the probiotics, prebiotics, fibers, all that stuff comes in. But I'm going to say this again. Yes, there are a couple of foundational probiotics that you can try out. But if you're really having digestive issues, you want to get tested. You want to get that microbiome tested so that when you're replenishing, you are doing it, especially with probiotics, you're doing it with the right stuff. Now, other things you can re-inoculate and replenish with are fermented foods if you tolerate them. So things like good quality yogurt or kefir. Now, that's dairy. You can get yogurt that's made with coconut milk. Goat's milk can be much easier to tolerate for a lot of people. Of course, stay away from the sweetened stuff. Go for the really high quality yogurts that are unsweetened, that come from grass-fed cows. Be selective. Things like sauerkraut, the kind that comes out of the fridge, not the kind off a shelf. Kimchi can be great. There are some really nice traditional foods that have natural probiotic in them that can be really, really healthy. The other thing that I like, and actually, it can come in the replace, restore or re-inoculate light or even in the next repair section. And that's something like bone broth, which I can't believe I haven't mentioned bone broth yet. And I've done a whole episode on gut health. Bone broth is going to be particularly healing to the gut. It's got all the nutrients, all the delicious nutrients that you need to heal that gut lining, especially if you're using gelatinous bones in there. And I like to put in, sometimes I'll put in some turmeric root and ginger root in my bone broth while it's cooking. It gives it great flavor and it also gives us some really nice nutrients. And it's really great for calming down the gut, right? Because ginger and turmeric are anti-inflammatory. So this brings us to the last stage, which is repair, repairing the gut. And this is where we're going to use things like alglutamine, zinc, omega-3. We want to make sure vitamin D3 is up. Aloe vera juice can be very, very, this is the aloe vera, the gel, not the leaf, leaf is bad. The actual gel from aloe vera can be very soothing to an irritated gut. If you get heartburn, deglycerized licorice lozenges can be really helpful. Things like demulsant herbs like marshmallow root, so marshmallow root tea can be really smoothing to irritated tissues from that reflex. And then we can get into the more advanced stuff. So things like peptides, there are some really great gut healing formulas out there. My favorite, you guys have probably heard me talk about it before, ultimate GI repair by Level Up Health. Yes, it's a bit of an investment, but it has everything that you need in it. So it is a very powerful tool. You could just do 30 days of that and probably if you've done all the other things we've talked about, if things are not too bad, it can be a really powerful tool to helping to heal the gut. And if you don't want to use peptides, because you know, peptides are still a new frontier for a lot of people, bioptimizers also has another product that is a powder that is fantastic. It's called Gut Break, I think it's called Gut Microbiome Breakthrough or Gut Breakthrough. We'll put the link in the show notes. It's a little jar, they've got it both in vegan formula and non-vegan formula. You taste really good. One of them is vanilla, the other one's chocolate. You take a scoop, you mix it in water and you drink it. It's delicious and it has everything you need in there. Again, just no peptides to heal the gut lining. So you don't have to be into peptides. If you're not into peptides, no worries. There's other solutions. People have been healing guts since the beginning of time. So I am a fan of peptides, but I also recognize that either people can't afford them or they don't want to go there. And if you're not comfortable with going to peptides, there are definitely some other fantastic options. Bioptimizer's Gut Formula is one of those strategies that I think is next level. And of course, I can't really finish this episode without talking about do bioregulators fit into the gut discussion? And they most certainly do. Now, bioregulators, for those of you who don't know what they are and haven't caught, as a matter of fact, last January, I released, I re-released a Bioregulator 101 episode. You may want to go back and listen to that. But before you do that, there are bioregulators that are specific to gut health. There's a stomach bioregulator, there's the liver bioregulator, there's a pancreas bioregulator. And we would, of course, always underpin them with a blood vessel bioregulator. Now, why do I think that bioregulators can be helpful for gut health? Well, think of it this way. If the stomach bioregulator is going to help the stomach to resume producing digestive enzymes the way it used to, that's going to be a plus. If the liver bioregulator helps the liver, which rejuvenates anyway, but basically helps to support the rejuvenation of the liver and restore proper function, that's a win. And then the pancreas, which is working so hard to generate all the insulin, generate the pancreatic enzymes, maybe it needs a hand. Maybe you've been using a JLP1 for a while. Maybe the pancreas could use some love. So supporting the pancreas, the liver, and the stomach, doing a 30-day run of those three bioregulators would, I think, is an incredible strategy. And I would do that once a year, twice a year, even three times a year for 30 days, just two capsules a day of each one for 30 days, every few months, I think is a beautiful way to support gut health. And it's not going to replenish the microbiome, but it is going to bring some attention and some love and some rejuvenation to those critical organs of digestion. Now, we'll put the link in the show notes of where I get my natural bioregulators, if that's something you're interested in. But like I said before, there's many different ways to skin this cat. What's most important is that we remember that we need to remove the things that are damaging the gut, and we need to be able to restore ourselves to a nutrient-dense, beautiful diet that is going to feed us properly. All right, that's it for gut health today, you guys. Hopefully, you got some value out of this episode. Let us know in the questions. Let me know in the comments, in the questions, wherever you're listening to this podcast, or come check me out on Instagram at Natalie Nittum. We'll be posting there. You can put it in the comments there. Or if you want to hang out with me and you want to continue this in any other conversation, you can come join me in my membership community. And we do live office hours in there. I have experts come in who talk, who've been on the podcast, and there's some crazy incredible practitioners that are already group members. It is one of the most supportive, incredible, knowledgeable communities I've ever been a part of, if I do say so myself. I learn stuff in there every single day. Now, if you're interested in the membership community, all you got to do is go to natnittum.com, my website, and you will see at the top of the page, there's the Longevity community. You can click on that tab, and that'll take you down to see what your options are in terms of joining the community. So thank you so much for being here, folks. I am so grateful for you guys. I'm so grateful to be able to do what I love every single day thanks to you. And let me know how your guts doing. Have a great year. Happy 2026. Hey, folks, just a quick reminder that all of the information presented in this podcast is for information purposes only. No medical advice, no diagnosing, no treatments suggested here. Before you try anything that you hear about or learn about here, make sure that you check with your medical provider.