NAD+ decline with aging and mitochondrial integrity
Discussed in 1 analyzed podcast episode across 1 show
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The Dr. Hyman Show · May 6, 2026
The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin
Geroscience hypothesis: aging as primary driver, diseases as secondary manifestationsHallmarks of aging: mitochondrial dysfunction, senescent cells, telomere shortening, epigenetic changes, proteostasisImmune aging: thymic involution, innate immune hyperresponsiveness, adaptive immune decline, inflammagingMitochondrial-inflammation bidirectional relationship and mitophagy activationUrolithin A: postbiotic metabolism, mitophagy induction, immune rejuvenation, muscle endurance
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