The 5 Pillars That Will Transform Your Health In 2026
69 min
•Dec 15, 20254 months agoSummary
Dr. Mark Hyman outlines five pillars for transforming health in 2026: nutrition based on whole foods, sleep optimization through circadian rhythm management, stress reduction via exercise and mindfulness, strategic supplementation, and a 10-day detox protocol. He emphasizes that food functions as medicine more powerful than pharmaceuticals, capable of rapidly reversing chronic diseases through gene expression and epigenetic changes.
Insights
- Food acts as informational code that regulates gene expression and biological software in real-time, not over weeks or months, making dietary choices more impactful than most medications
- Sleep dysfunction and stress are interconnected through cortisol dysregulation; addressing circadian rhythms and stress response is foundational to weight loss and disease prevention
- A 10-day elimination diet can produce 70% symptom reduction across multiple conditions by removing inflammatory foods and resetting the body's detoxification and immune systems
- Exercise addresses multiple hallmarks of aging simultaneously—telomere length, mitochondrial health, inflammation, and epigenetic age—making it comparable to a multi-drug intervention
- Nutrient deficiencies are widespread (90% of Americans deficient in at least one nutrient) despite adequate calorie intake, requiring strategic supplementation even with optimal diet
Trends
Functional medicine shift from symptom management to root-cause elimination through dietary intervention and lifestyle optimizationGrowing consumer awareness of nutrigenomics and epigenetics as drivers of health outcomes, moving beyond calorie-counting modelsPersonalized nutrition and biomarker testing becoming standard practice for health optimization rather than disease treatmentTime-restricted eating and circadian rhythm alignment gaining clinical validation as longevity and metabolic health strategiesWhole-food, plant-forward diets (80% plant-based) emerging as evidence-based approach for reversing metabolic disease and autoimmunityStress management and nervous system regulation recognized as equal or superior to exercise for chronic disease preventionSupplement industry consolidation around foundational nutrients (magnesium, vitamin D, omega-3) rather than exotic compoundsCentenarian research and blue zone studies driving mainstream adoption of movement-integrated lifestyles over structured exerciseFood quality metrics (regenerative, grass-fed, wild-caught) becoming primary health markers rather than macronutrient ratiosDetoxification protocols and elimination diets gaining clinical legitimacy for autoimmune and inflammatory condition reversal
Topics
Nutrigenomics and Gene Expression Regulation Through FoodCircadian Rhythm Optimization and Sleep ArchitectureCortisol Dysregulation and Stress-Induced Metabolic DiseaseElimination Diet Protocols and Food Sensitivity TestingMicrobiome Health and Prebiotic/Probiotic FoodsTelomere Length and Exercise-Induced LongevityMitochondrial Health and Energy ProductionPhytochemicals and Polyphenols for Disease PreventionTime-Restricted Eating and Metabolic FlexibilityRegenerative Agriculture and Food Nutrient DensityFunctional Medicine vs. Conventional Disease ManagementSupplement Protocols for Stress and Sleep OptimizationBlood Sugar Regulation and Insulin SensitivityAutophagy and Cellular Repair MechanismsEnvironmental Toxins and Detoxification Pathways
Companies
BioOptimizers
Magnesium supplement sponsor; produces Magnesium Breakthrough with seven forms of magnesium for absorption
Function Health
Real-time lab testing and personalized biology insights platform; Dr. Hyman is Chief Medical Officer
Cleveland Clinic
Where Dr. Hyman ran functional medicine programs including 'Functioning for Life' group that achieved rapid disease r...
Ultra Wellness Center
Dr. Hyman's clinical practice offering functional medicine services and patient care
People
Dr. Mark Hyman
Host and primary speaker; functional medicine physician discussing five health transformation pillars
Rich Roll
Podcast host and friend mentioned in discussion about 100-year-old guest discussing diet importance
Victor Frankl
Auschwitz survivor cited for philosophy on stimulus-response gap and personal choice in stress management
Robert Sapolsky
Primatologist and stress researcher; author of 'Why Zebras Don't Get Ulcers' on stress physiology
Dan Barber
Chef and founder of Row7 Seeds; breeding crops for flavor and phytochemical content
Gabor Maté
Trauma researcher cited for concept that trauma is meaning-making, not just events
Rick Warren
Referenced for advice that 'everybody needs a buddy' for exercise motivation
Pietro
95-year-old Sardinian shepherd example of functional longevity through daily movement and lifestyle
Quotes
"What you put at the end of your fork is more powerful than anything you'll ever find in a prescription bottle. It works faster, better and cheaper."
Dr. Mark Hyman•Opening theme
"Food, I don't even think we should call it medicine. It's like a miracle cure because it's so powerful."
Dr. Mark Hyman•Mid-episode
"Between stimulus and response, there's a pause, and in that pause lies a choice, and that choice lies your freedom."
Victor Frankl (cited by Dr. Hyman)•Stress management section
"The smartest doctor in the room is your own body and that's what you want to focus on."
Dr. Mark Hyman•Program conclusion
"If you don't move, you won't. Literally, you'll be dead."
Dr. Mark Hyman•Exercise section
Full Transcript
Coming up on this episode of the Dr. Hyman show, what you put at the end of your fork is more powerful than anything you'll ever find in a prescription bottle. It works faster, better and cheaper. Food, I don't even think we should call it medicine, it's like a miracle cure because it's so powerful. Before we, the holidays are supposed to be joyful, but for many of us, they're stressful. Between travel, family, busy schedules, and late nights, our bodies burn through magnesium fast. Magnesium is responsible for over 600 processes in the body, including sleep, muscle relaxation, mood, and stress response. Most of us are deficient without even knowing it. That's why I take magnesium breakthrough from bioptimizers. It has all seven essential forms of magnesium in one capsule, so your body can actually absorb and use it. This holiday season, give your body what it needs to feel calm and sleep better. Visit bioptimizers.com slash hyman and use code hyman to say 15%. To jump into today's episode, I wanna share a few ways you can go deeper on your health journey. While I wish I could work with everyone one-on-one, there just isn't enough time in the day, so I built several tools to help you take control of your health. If you're looking for guidance, education, and community, check out my private membership, the Hyman Hive, for live Q and A's, exclusive content, and direct connection. For real-time lab testing and personalized insights into your biology, visit Function Health. You can also explore my curated Dr. Trusted Supplements and Health Products at drhyman.com. And if you prefer to listen without any breaks, don't forget you can enjoy every episode of this podcast, Add Free with Hyman Plus. Just open Apple Podcasts and tap Try Free to start your seven-day free trial. What actually is a good diet? And I've written a lot about this. I wrote food, what type should I eat? The vegan diet. There's no guessing what I think. But essentially, it's whole real food. I used to do a lot of speaking in churches with the Daniel plan I did, and I used to say it's really easy and fair to eat. And I just asked you to have one question. Did God make this or did man make this? Did God make an avocado? Yeah, did God make a Twinkie? No. Did man make an avocado? No. It's pretty easy. Even a kid in kindergarten could figure out what to eat. So ask yourself next time you go buy something, who made this? Was it coming from nature? When God, or was it just coming from a factory somewhere? And then you should probably stay away from the stuff that's not actually made by God or nature. So you wanna eat whole foods, real food. Lots of plant foods. 80% of your diet should be unprocessed whole plant foods, vegetables, fruits, nuts, seeds. Obviously some grains and beans are good, some aren't. Like gluten is a problem, especially modern wheat. You might probably wanna stay away from that. You need to eat foods that have good fats in them, avocados, nuts, olive oil, fatty fish, like sardines, mackerel, herring. You also wanna eat a lot of fiber. So that's gonna happen naturally as you eat a lot of plant foods. You wanna make sure you have prebiotic foods, like plantains and artichokes and asparagus. And I even sometimes add that from a microbiome. You also want polyphenols for your microbiome. Things like cranberry and pomegranate and green tea and all these prickly pear and olive leaf extract and all these different things that you can use to actually increase the growth of the good bugs in your gut, because that determines so much of health. You're not only feeding yourself, you're feeding all those guys in there. And then you can also take fermented foods, things like tempeh and sauerkraut and miso and kimchi. These are all foods that are traditionally made in Dots because we had to preserve our food in the past. We didn't have refrigerators. So we had a way of preserving all this stuff. And also protein's important. Now, especially as we get older, now you don't want too much protein, but you want enough protein. And you want the right kind of protein. And I've written a lot about this, especially in my book, Young Forever. But there's basically, the cruel is a palm-sized, full-sized amount of protein at most meals. And this can be, you know, plant proteins, but often need a lot more. Nuts and seeds, grains and beans are okay. But they're lower quality. They don't have all the amino acids you need for, or in the right volumes for building muscle, particularly as you get older. So I like grass-fed meat. I like pasteurized chicken. I like pasteurized eggs. I like small wild fish. I like goat whey. These are my kind of go-to proteins. So that's what I think tofu, tempeh are probably the most dense plant-based proteins. But you want to eat the right protein. Now, what should we not be eating? Well, it's stuff that's not food. Obviously, there's another thing is junk food. There's junk and there's food. So obviously, if you see a label with 45 different ingredients, don't eat it. If you can't pronounce the ingredients, don't eat it. If you don't recognize what the ingredients are, don't eat it. You know, you can shop around the outside of your grocery store. There's a few key tips that you should just stick to. 100% never fall off of this. There's no high-fructose corn syrup every period. Why? Well, one is sugar. And two is a special form of sugar that does a lot more damage and is a lot more likely to cause harm. The next is hydrogenated fats. Never eat anything with that. And it's supposed to be not safe to eat according to the FDA, but it's still everywhere in the grocery stores. I don't know how they'd get away with this, but seven years ago, they said it's not safe to eat and it's still in the grocery stores. You can go figure. Anyway, I won't get into that. Refined vegetables, I just want to stay away from that. Stay away from additive chemicals, preservatives, pesticides. I mean, if you wouldn't sprinkle it on your salad or on your vegetables at night, well, why would you eat it? I mean, who has butylated hydroxy toluene in their cupboard? But that's a common preservative found in most processed food. Also, artificial sweeteners are really bad. They tend to cause bacterial overgrowth in the gut. They actually increase the risk of obesity and diabetes. You don't want to do that. And they'll wreck your health. So what's the number one take home philosophy? Just that simple question. Did God make this or did man make this? And ask yourself that next time you pick something up at the grocery store. Okay, so why is food the most important medicine in your medical toolbox? Why is it the most important thing you could be focused on for your health? And, you know, I actually was watching a podcast that I say with Rich Rolls, a friend of mine. And there was a guy who was 100 years old on there. And he's like, the most important thing is diet. And he is right. Now, it is the most powerful tool you have to change your health. What you put at the end of your fork is more powerful than anything you'll ever find in a prescription bottle. It works faster, better and cheaper. It has the power to influence and improve the expression of tens of thousands of genes to optimize tens of thousands of protein networks to balance your hormones, improve your brain chemistry, to upregulate your immune system and even to enhance your microbiome. And it works without any side effects, except good ones. So this is really a drug. And I know I was giving a quick story. I told the story before, but it's so important to understand how quick and fast this is. I had a patient, this patient illustrates this more than anything. She was part of our program at Cleveland Clinic. She came to one of our groups called Functioning for Life. She was 66, she had heart failure. She had angina, had multiple stents. She had type 2 diabetes on insulin for years, hypertension. I mean, you name it, she had it. Her kidneys were failing, her liver was failing, her liver was failing, you know, one liver, right? I do remember that from medical school. And she was so sick and she was this big. Her body mass index was 43, 30 is considered obese, 40 is severely obese and she just was enormous. And she took insulin shots every day. She came to CS and she changed her diet. And she did exactly what I'm gonna tell you to do today. And within three days of changing her diet, she was off insulin. And by the way, she was in a pile of pills that cost $20,000 a year for her co-pay. In three days, she was off insulin. In three months, she was off her medications. Her A1C, which is your average blood sugar, went from 11, which is like almost hospitalized, to five and a half, which is normal. Her heart failure reversed, her kidneys normalized, her liver normalized. She got her blood pressure pills and she lost a bunch of weight. And after a year, she lost 116 pounds and had none of those conditions and was off all of her medications. There is no drug on the planet that can do that. All those drugs were managing her diseases. Food, I don't even think we should call it medicine. It's like a miracle cure because it's so powerful. And I've seen this over and over and over in my practice. And I honestly, as a doctor, I've been doing functional medicine for a long time, okay, decades. And I think I was the first one to say, you are not allowed to see the doctor in my practice unless you also see the nutritionist. Because if I'm a doctor and food is medicine, then how am I gonna practice without a nutritionist? That is fundamental, fundamental to the premise of functional medicine. And there's five nutritionists that work with me in my practice. They're awesome. So anyway, let's get back to it. So what is food? You know, okay, it's protein, it's fat, it's calories, it's carbohydrates, it's fiber, it's vitamins, minerals. But it's so, so much more. In everybody's food, there's only thousands of informational molecules, like code that can upgrade or downgrade your biological software with every single bite. Literally, you change your biological software, you change your genetic expression, you change the way your hormones work, the way your immune system works, you change which bugs you're growing in your gut, depending on which foods you eat, literally in real time, not over decades or days, but literally within minutes. So it's so powerful, and we have the ability to speak to our genes through food. And I think this is why it's so important to understand how to use food as medicine. But by the way, okay, by the way, it's not suffering here. I'm not talking about eating wheatgrass shots and a bunch of oat bran or something. Like I'm talking about yummy, delicious, tasty, amazing, gorgeous food. I had a party for my office staff last night, and we had the most unbelievable array of vegetables and foods and dishes and flavors. And I mean, nobody went away going, oh, this was healthy food. They're not thinking, oh, this is healthy food, because it just tastes so good. So if it doesn't taste good, no one's gonna eat it, right? But actually food tastes good. And by the way, you might not know this, but flavor in food, and the reason why the food industry puts so many chemicals and additives and colorings and flavorings and sugar and salt in food is to make it taste good. How do you take processing ingredients and make them taste edible? You have to add all this crap. But if you eat real food, inside the food are the molecules that give food its flavor. So think about this. If you ever grew a garden or had a fresh tomato grown in your organic garden, and you went like a cherry tomato or something, you went at the end of the summer in August and stuck in your mouth. It's like an explosion of flavor. Whereas if you take a tomato, it was like grown in some hot house and shipped across the country, and it was designed to be fit in a box in a certain size and square and not squish. I mean, it looks like a tomato, but it doesn't taste very good. And the reason for the difference in taste, the reason is the phytochemicals, these plant compounds that produce the flavor. But guess what? Those phytochemicals that produce the flavor are also the medicines in food. So flavor and medicine in food go together. Not the flavor that you added about kinds of crap, but the actual flavor of the food, right? Think of a ripe peach at the end of the summer that melts in your mouth and squishy and juicy. I'm drooling already. Okay, so it is in the summer, it's peach season. So you wanna just understand that you wanna seek out flavor. And Dan Barber actually did a company called Ro7Cs where he created a company to improve the flavor of foods by breeding them to produce more flavor. But as a side effect, the way they get the flavor is through the phytochemicals. So I wanna sort of help you really understand this is so important. Now, the next question I wanna answer is what is this whole field of nutrigenomics? You might have heard about personalized nutrition, our nutrigenetics, nutrigenomics. This is the science of how food regulates your gene expression and your epigenetics. When you eat, it's literally sending messages to turn genes on or off. I'm gonna turn on the antioxidant genes, or I'm gonna turn on the anti-inflammatory genes, or I'm gonna turn on the genes that cause cancer, or I'm gonna turn off the genes that cause cancer, or I'm gonna turn on the genes that cause heart disease, or turn off the genes that cause heart disease. So we really think of them as like the food as the little signals and the code that is regulating your biological software. And you want a new operating system that's an operating system of health and well-being while you have to put in the right code. And the right code is the right food. So what messages are you sending to your biology when you eat a double cheeseburger fries and a Coke? What messages are you sending to your body if you're eating like we had last night, this watercress salad, we had this incredible watermelon gazpacho with mint. We had, oh my God, so many different things. Eggplant with all kinds of spices and sauces on it. It was so delicious. And spices also are full of these phytochemical flavor things. So there's so many ways that we should be thinking about how we regulate our body. What if you had, you know, fresh wild salmon and wild berries, maybe wild strawberries. Every time you have a wild strawberry, it's bursting with flavor. And fresh wild greens like they had in Icaria where they lived to be a hundred years old. And that's a very different set of molecules that you're putting in your body that regulate what's going on. So this is really about personal nutrition. It's about understanding how genes are affected by what you eat. And then also we have to think about how each of us are different. So, but as a whole framework, the power of food as medicine is huge. This time of year can be packed with connection and joy, but it can also be hard on our health. Stress goes up, sleep goes down, and we often feel tired, tense, or overwhelmed. One simple reason why most of us are deficient in magnesium. Magnesium is involved in energy production, calming the nervous system, regulating mood, relaxing tight muscles, supporting digestion and improving sleep quality. But most magnesium supplements only include one or two forms which your body can't fully absorb. That's why I take this as a reminder. Which your body can't fully absorb. That's why I take magnesium breakthrough from bioptimizers. It includes all seven essential forms of magnesium. So it gets into your cells where it actually works. I take it every night to support deep sleep and help my body manage stress, especially this time of year. If you wanna feel calmer, sleep better, and support your overall health during the holidays, I highly recommend trying it. Just go to bioptimizers.com slash hymen and use code hymen to get 15% off your order. So we know that poor sleep makes us less productive, it makes us tired, hard to focus. Basically having sleep deprivation is basically equivalent of being drunk. In terms of your performance, I read a study once where they were snipers who were excellent shots and that they had eight hour sleep, they were like 100% accurate. If they had seven hour sleep, they were like 95% accurate. If they had six hour sleep, they were like 70% accurate. And if they had a six hour sleep, they were like 70% accurate. And if they were like less than six hour sleep, they were basically like 50% it's like almost a hit and miss. So not good even when you're an expert in something you can't function when you're tired. So next to sort of nutrition exercise, and maybe even before it's somewhat argue, sleep may be the fundamental foundation of health and disease prevention and even weight control. So why is it so important? How does the sleep dysfunction lead to change as well? Is a very important hormone called cortisol, which is your stress hormone. And it helps when it's in balance to go up in the morning to get you energetic and focused and do the things you need to do for the day. And at night it's supposed to go down and you're supposed to calm down and relax. Now a lot of people have an inversion where their cortisol is on the morning, they can't get out of bed and at night they're tired and wired. Sound familiar? I've had you, some of the experience that I certainly have at different moments in my life when you get down in a bed you're exhausted but you can't fall asleep because you're just wired. That has to do with your adrenal glands. And they're designed to keep things in balance to regulate your weight, to moderate your stress response, to control blood sugar, regulate inflammation and regulate sleep and wake cycles. So when we're constantly in a state of stress we're actually often struggling with sleep because of the way in which it affects our sleep. So when you're thinking about it, when your cortisol is high, you're running from a tiger, you're in danger, you don't wanna be sleeping, you wanna be alert. And that's the problem. So if your cortisol levels are balanced and they're high in the morning and then low at night and your blood sugar stays even, we'll talk about why that's important. Because fluctuations in blood sugar often will cause midnight or middle of the night, awakening, but when your cortisol and your body's stress response are balanced and your pineal gland produces something called melatonin that pulses really strong in the afternoon and the evening which gets you ready for sleep and let your cortisol drop off and then you can feel calm and go to sleep at night and feel sleepy. And if you're healthy and balanced in your circadian rhythms, in your cortisol and melatonin cycles, you'll be fine. But if your cortisol is high in the afternoon or high in the evening, you might feel tired and wired, you wanna sleep but you can't. Or you might fall asleep because you're really tired and then you wake up in the middle of the night like between one and four. And that happens when you sort of go, go, go, go, go, go do your email, you're working, working, working, and busy and then you go to bed and you're like, and then you fall asleep because you're exhausted but you end up waking up because your body is still in a stress state, there's still high levels of cortisol. So how does stress affect your sleep wake cycle as well? It works in a lot of different ways. Psychological stress can be a big factor, right? Worries about family, work, money, physical stresses, lack of exercise is a stress, believe it or not, too much screen time, junk food, toxic lifestyles, hormonal imbalances, environmental toxins, all these drive increased inflammation, increased brain inflammation, and also increased cortisol. Because by the way, do you notice that when you eat sugar or starch, your body responds by jerking up the adrenaline and cortisol levels. So literally eating sugar is a stressful experience to your body, even if you're getting pleasure, and you don't think it's stressful and you're meditating while you're eating sugar, you're still gonna have high cortisol and high adrenaline. So what are the things that are the two most common things that are screwing up your sleep wake cycles? It's probably blood sugar imbalances and spikes and crashes and blood sugar and chronic stress. So what should you do to optimize nutrition so you can regulate your stress hormones through food and lifestyle? And how do you deal with actually regulating sleep throughout the whole night and get high quality sleep? So first thing is our bodies, whether we like it or not, are biological organisms and they run in circadian rhythms and they need to be balanced. So you have to live in rhythm. And I experienced the dangers of not being in rhythm when I worked in the emergency room. I would sometimes work seven in the morning till five at night shift, then I'd work at two in the afternoon till the two in the morning shift. Then I'd work at 11 o'clock at night to a seven in the morning shift, then I'd work an eight in the morning to an eight in the morning shift, 24 hour shift. I was all over the place. And my whole system became just regulated. And ultimately it led to chronic fatigue syndrome and a bunch of other stuff. My system just kind of collapsed because I was pushing through all these circadian rhythms which have to be in balance for you to be healthy. And whether we like it or not, we tend to do a lot better from our health perspective if we go to bed at the same time, if we wake at the same time, if we eat at the same time, our bodies are designed like that. So you wanna make sure that you actually don't eat before bed because that's the worst thing you can do. But you need to make sure you're having meals or in a regular time space. So don't eat three hours before bed. Don't eat a heavy meal before bed because that guarantee you that'll screw up your sleep. Also carbohydrates, I think if you wanna actually eat some starchy things like sweet potatoes or some more starchy foods and you can handle it metabolically, make sure you do it at night because the serotonin levels go up and it helps with sleep when you have your carbohydrates. But still don't eat white flour, sugar, all that processed food. Also, not eating enough is stressful. If your body's not getting enough food, it's also considered a stress. Now you can do time-retreat to eating and you can sort of narrow the window which you eat for longevity purposes and so on. But you also want to make sure you're getting enough food and not actually starving because that will increase cortisol and you'll wake in the middle of the night. Now if you wanna lose weight, you can use what I think is probably the most effective treatment ever found which is the 10-day detox diet to help people lose 120, 130, 200 pounds. It's like a gastric bypass without the pain of surgery, vomiting and malnutrition. Another thing you can do is get stuff out of your head. You write your voice down at night. So get a little piece of paper or journal or maybe in your phone. Write down all your worries, what you have to do. Your days should be organized the next day. Free up your mind so you can actually let go of things and go into a deep breathful sleep. Next, you can try a number of supplements and things that I found very helpful. Magnesium is super important. It's the relaxation mineral. It helps regulate the stress response, helps you regulate cortisol, helps relax your muscles. I recommend 2 to 400 even more of magnesium glycinate before bed. Glycine also helps with sleep, so you can use glycine. And you can use that to help relax the nervous system and your muscles. Next, trisomelatonin. Melo out with low melatonin. You can use half to up to two to three milligrams of melatonin at night. And that can often help you reset your circadian rhythms, particularly with travel. Also, ashwagandha is an Ayurvedic herb that can be really powerful for resetting cortisol. I use a product called Cortisol Manager, which helps at night to reduce the stress response and improve sleep quality. Also, make sure, as I said, to get in rhythm, you know? We can sleep at the same time. Try to go to sleep before 10. That's the best sleep you can have is before midnight, believe it or not. So, get in bed by 10, try to be asleep shortly thereafter, 11 at the latest, and try to wake up at the same time every day. Also, make your bedroom completely sleep supportive. For example, make sure you have eye shades or blackout shades on your windows or eye shades on your eyes, ear plugs if it's noisy. Make sure you really take care of creating a carefully controlled environment. Next is caffeine. You know, some is tolerate okay and metabolize it, others don't. So, I encourage you to sort of maybe stop after breakfast coffee, don't have coffee throughout the day. That's particularly important. If you're still struggling, I would probably just stop coffee and caffeine altogether. Alcohol definitely screws up sleep. So, if you wanna sleep well and you're not sleeping well, quit alcohol, just get off it. Make it interrupt sleep and creates poor sleep quality. Also, sunlight is basically great medicine. You know what I mean, it's sunlight. I'm gonna go to sleep, no, but 20 minutes of sunlight in the morning without sunglasses on, outdoors, not behind a window, has a big effect on your circadian rhythm. So, we are a photo-biomodulating organisms. The light affects us, it regulates our biology. And it's important to make sure you have a good 20 minutes of light exposure in the morning. Chronic stress is dent-like. It kills us, literally kills us from heart disease, cancer, dementia. I mean, just literally being stressed and having high stress levels chronically will shrink the memory center of your brain called the hippocampus. It also makes you gain weight and it causes you to be diabetic and it causes a whole host of other things including depression and infertility and sexual dysfunction. I mean, you name it, stress is a killer. So, we now understand how stress impacts our biology in a real practical way. It is in fact the biggest thing that's driving so many of the dysfunctions we see around chronic illness and it either makes worse or causes most of the things we see every day in medical practice. How well, stress jacks up your cortisol levels which then causes your muscles to waste away, your blood pressure to go up, your blood sugar to go up, increases belly fat, causes your memory to go down and you see this phenomenon of weight gain and some resistance and diabetes. Ultimately even type three diabetes which we are now referred to as dementia. So, when you also are stressed, you produce adrenaline and adrenaline also makes you feel hyper, anxious, irritable, gets your heart rate up, your blood pressure up, causes your blood to clot more likely, it damages your brain's memory center and just causes a lot of bad problems. So, if you're thinking about your daily life when you are going about your day, if you start off the wrong way, you're gonna be in trouble and one of the things we don't realize is that stress is also controlled by what we eat. Our diet plays an enormous role in our stress response and so, when we eat certain foods, it literally jacks up adrenaline and cortisol. What foods are those? Sugar and starch. Basically anything that turns the sugar in your body is seen as a biological stress. Even if you think you're happy and relaxed while you're eating it, the consequences in your body are just like those of when you're attacked by a mugger or you're being chased by a tiger. The real physiologic responses that happen in relation to our daily lives are no different depending on what the stress is. So, whether you're running from a tiger or being upset with your spouse or you imagine somebody's mad at you and they're really not, the stress response is the same. In fact, stress is defined as the real or imagined threat to your body or your ego. So, it could be a real threat to your body like a tiger chasing you or it could be an imagined threat to your ego. Maybe you think your boss is mad at you and is gonna fire you, but actually doesn't think that at all and wants to give you a raise. You have the thought, the thought creates a stress response. So, our thoughts create our biology and we have to learn how to manage our minds in order to manage our biology. And so, let's talk sort of a little bit about diet again. Because what we found from the studies is that, when you eat food, it's not all the same. Food is information, it's not just calories. And the information in processed food, in starch and sugar increase our stress hormones, adrenaline and cortisol. And I remember one study they looked at overweight kids, I think boys, and they teach teenage boys and they gave them three different breakfasts, an omelet, steel cutouts and regular oats. What was interesting is that they were all identical in calories. So, the calories are the same and what they did was they had these kids, why don't you go in a sitting room and hang out, read, play games, whatever you wanna do. But when you're hungry, you just hit this button and we'll bring you food. And so, what they found out was when the kids had the oatmeal, they ate 81% more food than the omelet, even though it was the same calories over the course of the day. And with the steel cutouts, it was still 51% more food. But what was interesting was that they also had a catheter in their blood vessels and they drew their blood every little bit. And they found that when the kids ate the oatmeal, it was like a stress response in the body there. Not only their insulin and blood sugar went up, but their adrenaline and their cortisol went up. So, when we eat refined foods, they are hugely damaging. So, just in the same way, you can eat foods that actually help reduce your cortisol level. You can actually balance your insulin levels. You can actually reduce adrenaline by eating foods that help you calm your nervous system, which are whole real foods. Good, healthy fats like olive oil, avocados, nuts and seeds, high quality protein, regeneratively raised animal foods, eggs, chicken, fish, regenerated raised meats. You know, you can hold beans and whole grains can be very calming and helpful. Although if you eat too much starch and your insulin resistance, it can still be a problem. And then of course, all the plant foods, vegetables, they just are super full of phytochemicals, anti-inflammatory compounds, stress-reducing compounds and they're really powerful. So, when you shift your diet, you're literally gonna change your stress response and change your biology. So, what can you do other than looking at your mindset? Because a lot of the stress we respond to is the creation of our mind. You know, Gabramate, who's written a lot about trauma, which is real trauma, he says, trauma's not what happens to you, it's the meaning you make from what happens to you. So, two people can experience the same event and have very different responses and it can be registered very different in their biology. So, it's important to understand that you have to get your mind straight. And that's not as easy as it sounds because we are kind of conditioned to believe our thoughts and you know, my friend, Daniel Amann says, you know, we should stop the ants in our head, the automatic negative thoughts. Easier said than done, but it's an important practice. Start witnessing and looking at your mind. And some of the practices that I'm gonna share with you now are very effective in helping us reset our minds as well as our bodies. The first is, I deal with the root causes of stress, right? So, there can be physical stresses like a disease. I mean, I had mercury poisoning, Lyme disease, mole toxicity, these create a stress in the body. So, you have to deal with whatever true physical stresses there are and get rid of them. Gluten, nutritional deficiencies, all the things that are really driving so much disease. And we see this in functional medicine and it really is looking at the whole scope of what creates balance or imbalance in the body and dealing with that. The ones you've done that, and there are no sort of objective external stresses. How do you start to reset? Well, you have to learn to actively relax. It's something we don't get taught, we don't have to sleep and eat and exercise, but most of us don't understand that we have to actively relax. It's not just sitting on a couch watching TV. It's actually helping your body get into what we call a parasympathetic state. And this is not as easy as it sounds. You can do it through meditation, you can do it through a breath work, you can do it through massage, you can do it through prayer, through chanting, through yoga, through various kinds of things that help your body reset your nervous system from an overactive, stressed, sympathetic response to what we call the relaxation response. Meditation is a very powerful tool. It's available to all of us. It's free. You can learn how to do it online. There's courses and programs. You can read a book about it. It's not that hard to do. It's basically just sitting and watching your thoughts and not getting caught up in them but letting them pass using your breath as an anchor or a mantra. There's a lot of different techniques out there. Exercise also is a powerful stress reducer. Think about it. When you're running from a tiger, you're producing huge amounts of stress hormones and then you run and you burn them off. That's what happens is a book called Why Zebras Don't Get Ulcers by Robert Sapolsky who studied baboons and stress response actually and the hierarchy in baboon societies. And I highly recommend this book, A Primate's Memoir which describes his research but he wrote another book called Why Zebras Don't Get Ulcers which is based, oh no, I think that was written by John Kabat-Zinn. Sorry, no, I can't remember. Anyway, one of those guys. And the book basically said, when a zebra is out there eating his grass and hanging out and there's all other zebras and the lion comes, starts chasing them and they all run like crazy, highly stressed. And then the lion catches one of them and then the lion eats the zebra he caught. And then the other zebras just go back to eating the grass even though the lion's still standing there. So they discharge the stress. We don't, we continue to accumulate the stress. So exercise is a great way to reduce depression, anxiety, improve mood, to reduce stress response in the body. And that's why you often feel relaxed and calm after exercising. Other techniques are really good, breath work techniques, saunas, cold plunges, a lot of things that now are being used to help with longevity and biohacking also help to reduce the stress response. My favorite is a hot steam and a cold dip. And that really just kind of cuts all the stress for me, a hot bath with Epsom salt, very easy to do. There's also some supplements you can take. We use a lot of nutrients when we're stressed, vitamin C, the B-complex vitamins, vitamin B5, zinc, and magnesium. Magnesium is so important. It's the relaxation mineral. So I highly recommend that people take magnesium regularly to calm their nervous system. Herbs can be very helpful. Adaptogenic herbs can help you manage stress. The astronauts were using it. And the Russian astronauts often took these compounds like rhodiolus, hiberniginousine, cortisep, ginseng, ashwagandha. These are what we call adaptogenic herbs that help modulate the stress response. Also adaptogenic mushrooms, shaga, and reishi, and many, many others are very effective for helping modulate the nervous system. Now look at your mind. Find a way to look at your beliefs, your attitudes, how you respond, think about choices you have. I think Victor Frankl, who was an Auschwitz survivor, said between stimulus and response, there's a pause, and in that pause lies a choice, and that choice lies your freedom. And I think all of us have just kind of collapsed that stimulus response, or were just reactive instead of slowing down and looking at our beliefs, our thoughts. And he and in the concentration camp chose not to be angry or mad at his Nazi captors. I remember when I was a young medical student, I went to Nepal and I met with a Tibetan doctor who'd been in a Chinese gulag for 22 years, and I said to him, I said, what was the hardest part about being a prisoner in this Chinese gulag? And he said, well, there were a few times when I thought I would lose my compassion for my Chinese jailers. And I thought, wow. This guy was in jail for 22 years in a gulag, and that was his biggest stress, was thinking that he could lose his compassion for his Chinese jailers. So that just shows you the power of the mind to relate to your environment in quite a different way. So let's talk about what are the biological systems that are improved by exercise? It has to be the right type of exercise, the right dose, right frequency. And we'll talk about what that is, but it improves the health of your immune system. It boosts the number of your mitochondria, the powerhouse of your cells. It balances your blood sugar and your insulin, your adrenal glands, your thyroid, your sex hormones. It helps you improve detoxification, your circulation, your lymphatic flow, and even optimizes your microbiome. That's right, your gut bacteria. It also does some amazing things about the hallmarks of aging. Now in my new book, Young Forever, here it is everybody, super excited about it. It's out February 21st. And in the book, I talk about something called the hallmarks of aging. We've covered on the podcast a little bit. These are the things that go wrong as we age that underlie all disease. If we cured all cancer and heart disease from the face of the planet, we might extend life by five to seven years. But if we address the hallmarks of aging and the causes of the hallmarks of aging, we might get 30 or 40 years of life extension. And you know what the deal is about exercise? It addresses many of these hallmarks. For example, it increases telomere length. It reduces inflammation. It improves your mitochondrial health. It impacts your nutrient sensing pathways, like insulin signaling and MTOR and NPK and CER2 is things we've talked about. It also improves your epigenome and reverses your biological age. Now, you might be going, well, what do I have to do? Run a marathon every day? No, you don't. It doesn't take a lot of exercise. Even starting with something as simple as 10 minutes a day can add a significant benefit to your health. And if you do more, more vigorous exercise, interval training, strength training, you can extend your health span by leaps and bounds literally. You can stay fit and strong and functioning well into your 80s, 90s, 100s. I just read something pretty interesting that right now there's about half a million centenarians around the world. And pretty soon, by I think 2050, there'll be about three and a half million people living over 100 years old, which is pretty amazing. There's two of the oldest people now around about 115 years old. So many of us will be able to reach that age. So if you look at what you need to do, combine with diet, exercise is really the most powerful tool for staying healthy and extending your life. My mom used to say, whenever she had the urge to exercise, she would lie down to let it run away, which I think she got from any young man or some comedian. But she followed that advice, unfortunately, and she didn't exercise, despite my how near. Of course, parents never listen to their kids. I mean, kids, whatever, something like that. Parents never listen to their kids. And she ended up being pretty frail and disabled last day of their life and not too functioning. So when you start thinking about how to take this approach of incorporating movement and exercising your life, you can get really amazing benefits. I'm just gonna kind of go through them because they're just so profound. It actually unlocks the body's longevity switches, the regenerative and reparative systems that are built into our biology. It activates all the longevity switches that I talk about in the book, particularly the four that have to do with nutrient-sensing pathways that are sort of meta to everything else, insulin signaling, mTOR, which is really important in terms of autophagy and cleaning up your cells. Sertuans, which are important in DNA repair, and also NPK, which helps regulate blood sugar, insulin sensitivity, inflammation, and many other things. So it's pretty, pretty darn exciting. It also activates the body's antioxidant systems. It improves your cognitive function and your mood. It supports, I mean, they found that just walking, helps prevent dementia, which is pretty cool. It supports your microbiome. It reduces inflammation. It helps you produce more mitochondria and help them work better and be more efficient and have better function because mitochondria is where you make energy and as you get older, you lose energy, so you wanna boost that. It also keeps you strong and functional. You know, I just came back from skiing out in Switzerland and I had a really great time. It was a privilege to be able to go there. And I was amazed. Like, I was just skiing along like I was when I was 30 or 40, and I was probably going a little too fast, but you know, I like to do that. And, you know, I felt strong and able to do it and it was keeping up with people half my age. So I think the body has the capacity at NINI to do this. It also makes you happier and improves your mood and even improves your sex life, believe it or not. So what does the research say? And let's talk about some of the NINI gritty about how it works. If you really, you know, maybe you wanna know about the science, maybe that'll motivate you. I've probably just motivate most people, but it kind of gets me all excited. I kind of like that. I'm a little weird, but it really, the research is just, it's just unbelievable about exercise. When I started to dig into, you know, obviously you can look at exercise and anything and search on PubMed and learn about it. But I started to look at exercise and longevity and what it does. So we covered a little bit of this, but I wanna sort of expand on it. It improves your telomeres, which are little caps at the end of your chromosomes that start to shorten as you get older and shorten your life. It actually lengthens your telomeres by exercising. It protects your telomeres. It optimizes all these longevity switches like AMPK, which regulates blood sugar. People say, oh, I'm gonna take mid-formin for longevity. Well, exercise is way better than mid-formin for regulating AMPK. It also activates sirtuins, which help the DNA repair, reduce inflammation and improve your blood sugar control, which are really important. It also improves your cardiovascular and heart health, we all know, it reduces the risk of heart attacks and strokes and improves your brain function and cognitive function. It also helps certain types of cancer. As I said, we see the regulation of our biology through exercise being mediated through all these mechanisms that have to do with immunity and cancer prevention. So it's super great. And of course, it extends your health span and your lifespan. I remember being a Sardinian, I mentioned this guy, I think before, but his name is Pietro, he was 95 years old, and he was like a shepherd and he was just running up and down the mountains all day, five miles a day in this really rugged terrain. And he was bolt upright, booming voice, clear eyes, strong and mentally sharp. And I was like, wow, this guy's 95 years old. Unless you're 95 in America, barely can kind of walk across the street or get from their bedroom to the bathroom. And here he is, running up the mountain. So we have the ability to do that. And he exercise every day as a shepherd, not quote, exercise, but he just does his life. It also, it's incredible for diabetes, for blood sugar control. I mean, just walking after dinner is a great way to keep your blood sugar down, helps you become more insulin sensitive. And very importantly, it helps you build muscle mass and function because as you get older, you lose muscle. It's called sarcopenia, and that leads to all these hormonal and metabolic changes that accelerate aging and lower testosterone, high cortisol, the stress hormone, higher blood sugar, worsening cholesterol. I mean, just lower growth hormone and increased cortisol. Like I said, it's just, it's really bad news. So building muscle is really important and that's clearly only done by exercise. So hopefully, listening to all this, you realize you can't afford not to move. My basically philosophy is if you don't move, you won't. Literally, you'll be dead. So how can you actually incorporate more movement? What can you do without having to drag yourself through the gym? Now I go to the gym sometimes, but I rather play. And I think there's a lot of options and you can just do simple things. Like start with simple things, even five minutes a day. If you don't have five minutes a day to do something, there's something wrong with your life. So you better look at that. So, you know, for example, I figured out I couldn't do 10 push-ups when I was 50. So I started, I'm gonna do push-ups. So I take a shower most days. So I basically would wait for the shower to heat up because it was, I live in a barn and it's really tall and takes a while for the water to get upstairs. And I would do push-ups and I went for me, well not every 10 to be able to do almost 100 push-ups without stopping. So we can train our bodies and it's really simple. Or maybe while your coffee's brewing, maybe do some stretching and yoga. Walk or bike instead of driving. In many, many countries they do this. I just met this guy who was a CEO of a big company and he lived in Switzerland and he, I mean, he runs a six billion dollar company and he rides his bike straight up the hill, or the match in the mountain to work, 2,000 feet elevation every day. And he's in incredible shape. He's 53 years old and is VO2 max, which is a measure of fitness. He's that of a elite athlete and someone who's like half of his age. So it's very impressive. You don't have to sort of do something like that, but just parking further away in the parking lot, taking the stairs instead of the elevator, the escalator, just simple things to start moving. Also try a standing desk or a stability ball. If you're at a desk, you sit on a ball, it kind of helps you move and move your body and increase your core strength. I have a friend, Mike Royson, who was at Cleveland Clinic with me and he used to have a treadmill desk. He was on calls and working on his computer and walking all day long, which is impressive. Make your leisure time active time. So if you're watching TV or movie, maybe put a stationary bike in your house. I remember I worked in Idaho as a family doc and there was this patient that came in and she lost like a hundred pounds. I'm like, what happened to you? And she's like, well, I decided instead of sitting in front of the TV and eating all day, I would get a stationary bike and just ride the bike all day instead of eating. She did and she lost a hundred pounds. So pretty impressive. Maybe also you can listen to podcasts and an audiobook or do something like that when you're exercising or taking a walk and just makes it more fun and motivating. And also do it with somebody else. As my friend Rick Warren said, everybody needs a buddy. So it's important that if you maybe are having some trouble getting out there and doing stuff, find somebody else to do it with. It's much more fun for me to play tennis with somebody else or play basketball or go on a bike with somebody else and do it by myself. So I try to do it with friends and it's way more fun. Maybe pickleball is the latest craze. Join a pickleball league and go outside and just do fun stuff. So this is a 10 day detox. You're basically taking out the bad stuff and putting in the good stuff. You're taking all the foods that cause inflammation that are toxic to your system, that are inflammatory, the best for your gut. And you're putting in foods that actually help reset your system. Well, and it's pretty much a very simple approach. It's lots of veggies, so mostly veggies. Lots of good fat, lots of fiber, lots of good clean protein. And what does that look like? It's tons of non-starchy veggies like broccoli, any kind of veggies. I think of it's not a basically a potato. You know, sometimes potatoes are okay for people. Avocados, good fats, avocados, olive oil, nuts and seeds, lots of good protein, grass-fed, organic, regenerative meat, fish, chicken. Sometimes, you know, for vegetarians, you can vegan, you can use plant-based proteins like tempeh or non-jammu or organic soy, tofu. Those are the most dense sources of protein, but you do need protein that you detoxify. So for the 10 days, you're gonna be getting rid of all the other junk, right? Processed food, other carbs, sugar, dairy, coffee, gluten, alcohol, pretty much actually all grains and beans. And the reason we get rid of grains and beans they're necessarily all bad is a lot of people have issues. A lot of people have issues with their gut, a lot of people have issues with inflammation, a lot of people have issues with gluten, a lot of people have issues with insum resistance and prediabetes and obesity, and they can be problematic for these people. So basically, get off all the bad stuff. Now, it's not calorie counting, you can eat as much as you want. We're not like crazy, how much macronutrients and percentage, some percent of that. No, it's just pick the right foods and we focus on what to eat. You don't have to focus on how much to eat, right? So when you look at your plate, it should basically look like this. Three quarters of it should be non-starchy veggies. And I usually often will put two or three veggies in my dinner. I'll make mushrooms, I'll have a broccoli, I'll make some, maybe a salad. So I'll have lots of veggies and I'll have a portion of protein that's essentially the size of my palm. Four to six ounces, which is really 30 to 40 grams of protein. Now that's a good amount of protein, but you don't need that much if you're having an all protein. It should be very generally raised, should be pasture raised chicken, wild caught fish, should be low mercury, obviously all that. And we'll put all that show notes, lots of good fats with dinner, like avocados, nuts and seeds, olive oil in your veggies. You can even use, for example, ghee, which is a kind of a butter, but it actually has the inflammatory proteins removed, casein and whey. It basically has just the fat. It's called clarified butter, very common. You can get my book, Tending to Talks Diet. You can get the Tending to Talks Diet Cookbook, whatever you want, we'll put all the show notes and links together. I do call this Tending to Talks Diet, but sometimes you need to do it longer, like two weeks, three weeks, 10 months, maybe even 10 years depending on the situation. But we're gonna talk about the 10 days and how powerful that can be to transform your health. Now, I find that most people have never connected the dots between how they feel and what they eat. They walk around with what I call FLC syndrome. That's when you feel like crap. That is a big problem for people. What do I mean by that? Well, you might be tired, sluggish, you might have brain fog, maybe have digestive issues, reflocked, heartburn, irritable bowel, maybe have nasal congestion, sinus issues, muscle aches, joint pains, headaches, insomnia. Should I go on? Rashes, acne, I mean, it goes on and on and on. Many of these things are caused by food. And the only way to know is to do a total body reset. If I'm hitting the reset button on your commuter when all the systems are jammed, it's a complete reboot. How do you do a reboot? It's very powerful. And most people have never experienced this and this is what I love to do with people. And I actually run programs all around the world where people can come and actually experience this. We do programs where we have people do this. Just in five days, not even 10 days, people have a 70% reduction in all symptoms from all diseases. Now I'm gonna put in the show notes the medical symptom questionnaire that I use in my practice, which essentially gives you a score based on the degree and frequency and severity of symptoms. So if you have a headache, is it zero, meaning never, or before I get it all the time, maybe it really bad, or some version in between. And then you get a score at the end and people have a score of 60, 70, 100. It should be less than 10, maybe even zero, ideally. I wish I had symptoms, it's not normal. We're human beings that suffer this much. And that's really why I created this book and the program, the 10 day detox side, because I was doing this with my patients and seeing such incredible result. So I do this personally, regularly. I do it at least two or three times a year. Four times a year to really reset my system, to kind of get my body back on track, to get rid of all the bad stuff, put in all the good stuff. Now I wanna walk you through how to do this. I'm gonna teach you how to hit the reset button, reboot your system, and to optimize your biology to help your gut, to help your detox system, to help your immune system, to help reset your nervous system, and it's powerful. So if you wanna really see how your body can feel and get rid of what we call FLC syndrome, I would do this. Most people are like the frog that's in cold water where you turn the heat up slowly and it starts to boil to death. We just kind of get used to it and think it's normal. These symptoms are not normal. I wanna do this with a junior high school once and the teachers are like, well, we might have to get permission from the parents to see if it's safe. Maybe they don't want their children doing this. I'm like, what is it safe to eat fruits and vegetables and nuts and seeds and protein and cut out sugar and starch and processed food? I mean, they should get a note that it's permission to eat the junk food that they have in school. It's gonna be the opposite. But anyway, yes, it's very safe. Anybody can do this. And some people, by the way, need more certain things for other things, but basically, this is a very universal approach to resetting your system. A second pillar, aside from what you eat, the food is really important. And anybody that need to be approaching the morning, you need to make sure you get rid of sugar and starch in the morning, super important. And then people start their diet, their day with carbs, which is the worst thing you can do, sugar-sweetened coffee, teas, cereals, muffins, bagels, breads, that. Second pillar are your daily habit. Essentially, mom's a pattern of eating and living that puts your body back in rhythm. It helps you reset your nervous system. And there's few really important habits as part of the 10-day detox. One is when you eat and also when you sleep. Let's talk about when you eat. Now, when you eat might be as important as what you eat. So many of us don't eat in the right pattern. We tend to eat all day long. We tend to snack. We tend to eat before bed. We snack late at night. It's kind of bad. So basically, when you eat, it's very important. Research shows that doing that can really be bad for your health if you eat at night. So the first is make sure you give yourself at least 12 to 14 hours between dinner and breakfast. So dinner is six, breakfast at eight, that's a 14-hour fat, okay? If you eat at six and then you keep snacking all night, that doesn't count, right? And it's the most simple form of what we call time-restricted eating. And it's basically giving our body a rest and getting the body to reset. And I wrote a lot about this in my book. Young Forever, but basically, there's a whole process at night that happens called autophagy and clean up and repair, you wanna get your body the ability to do that. The next is food. Now, you can do a breakfast if you're eating, for example, dinner at six and breakfast at eight or so, that's a 14-hour fast. Really important to have protein in the morning, on not carbs and sugar. Also, not eating three hours before bed, it's really important. So most people eating snack after dinner, don't do that. At least three hours at the time you eat and you go to sleep. That way you will lose weight, your body can repair and heal instead of trying to digest and store the food. What about sleep? Sleep is one of the most underrated pillars of health. It's probably even before exercise, meditation, maybe even for nutrition, because when you don't sleep, well, you're gonna eat tons of sugar and carbs, you're gonna crave more. So you wanna focus on sleep and restore to rest. We know that getting in a routine of waking and sleeping can help with a deeper, more restful sleep. So try to take the same bedtime every night, try to get off your screens for an hour or two before bed, keep your room, or use blue blocker glasses, keep your room dark and cold, probably at 6-5 or 6-8. Really important because your body does much better with sleep at night. Try to relax at night with meditation, do a bad imagery, do a breath work, stretching, journaling, gratitude practice, whatever you like, but do something, very important. So your evening routine should be like, set a bedtime and sit over the 10 days, turn your phone off and get out of your bedroom, try to be off for at least an hour or two before you go to bed, and then use the time at night to read, to journal, to meditate, to connect with people you love, and just kind of wind down. The third pillar is extra support we need on the journey, right? Now, we all need nutrients. They're called vitamins because they were vital amines, vital to life, right? And so we've seen a dramatic reduction in the nutrient density of our food. Our organic matter's gone out of our soil. Nutrients can't be extracted. Foods travel long distances. We have commodity crops that you're bred to actually breed out the nutrients and in the starch and yield. And so foods aren't as nutritious as they once were, and probably 90% of Americans, according to the government-owned surveys, are deficient in one or more nutrients at the minimum level to prevent deficiency. So how much vitamin do you need to not get? Rickets, not very much, like 30 units. How much do you need for optimal health? Probably three to 5,000. So we need to really probably focus on nutrients, and even with a perfect diet, because none of us are hunter-gatherers anymore, or we don't have the food that we never ate, and I'm initially into cleaning. We need the basic supplements. We need a basic set of supplements. A multivitamin mineral foundational. Magnesium, a lot of us are deficient, probably 45% or lower deficient magnesium. We're involved in over 300 different enzymatic reactions. Super important helps your lacticid nerves, just in that night, help you calm down. Also, people get constipated sometimes when they change their diet, so taking magnesium citric can help. And lastly, vitamin D. It's also beneficial, but vitamin D is really important. Vitamin D, over 80% is lower, deficient in vitamin D. It's involved in so many different things in the body. So really important, and it helps your mood, helps your muscle function, helps your brain, helps your energy, helps inflammation, autoimmunity. It's just super important. And most of us are low. Fish oil is also important, and I often recommend fish oil to people, or omega-3 fat. So what are the program steps in a 10-day detox? What should be the 10th? And then we're gonna go through this. The first step is to eat from the 10-day detox approved list for 10 days. So eat, what I'm telling you, eat whole foods, whole food-based shake in the morning. You could add protein powder, aggressive protein if you want. I have aggressive protein called super simple protein, but you really need to make sure you have good breakfast. Second is commit to daily habits, right? Take your destiny of eating window, right? You want a 12 to 14 hour overnight fast, which means eating within a 10 or 12 hour window. Don't snack before bed. Try to have the same bedtime, get off your technology an hour or two before, practice some active relaxation, huge impact on your health. Step three is add in the supplements. Now you don't have to do this, but I really encourage you to have a multivitamin, magnesium, vitamin D, and potentially fish oil. And we're gonna list which products you should take in the show notes so you have it all listed there. Also, what you should eat and what you should avoid during your 10-day detox, let's go through that. So here's the full food list. You can bring it out in the show notes, you can take it with you in the store. It's in the book, the 10-day detox, it's in the 10-day detox cookbook. But essentially, here's what you should eat and what you should actually get rid of. What you should eat is protein, you need to write protein, right? So grass-fed or originally raised meats is great. You can have a path-raised lamb, beef, bison, venison, elk, grass-fed beef, postures chicken, turkey, duck, all that's fine. What you should avoid is conventionally raised chicken and poultry and eggs and so forth. And by the way, you can also have eggs if they're path-raised eggs. Meat, get rid of all processed meats, deli meats, all conventionally raised feedlot meats, get rid of all that stuff. But about fish and seafood. Lots of small fish are good, big fish are bad, right? Big fish like swordfish, tuna, fillet and sea bass, halibut, most farm-ish fish are pretty bad for you. What you should be consuming are things like the, I call this mashed fish, a small wild salmon, sardines, anchovies, herring, mackerel, you can have black cod, shrimp, scallops, trout, all of that's fine. Eggs, as I said, pasture's eggs are fine, non-organic, regular eggs are not fine. What about nuts and seeds? Very important, almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia, pecans, pine nuts, pistachios, walnuts, all that's great. You can even have tic-hownins, chocolate, not actually chocolate, but for a shot and comes from. Seeds are great, chia seeds, flax seeds, hemp seeds, pumpkin seeds, sesame seeds, sunflower seeds, pumpkin seeds, all great. Nut butters also great. So unsweetened nut butters, so almond, cashew, pecan, macadamia, I love macadamia, walnut, all that's great. You also eat beans if you're a vegan and you wanna do this, you can use GMO-free or non-GMO tofu or tempeh as your protein. What you should avoid are nuts that are with sugar, they're cooked in oils, that are with basically canned stuff, a lot of nut butters have sugar, hydrogen, fats, peanut butter, peanuts can be okay, but I would say mostly avoid peanuts because they have afotoxin and they often are rancid and so you wanna be careful with that. What about oils and fats? Well, the ones you wanna use are organic avocado oil, you can use organic coconut oil for cooking, grass fendue, if you wanna use tallow, lard, ducks at chicken fat, that's okay as long as they're path-based or originally raised for salads and you can use different kinds of oils like almond oil, flax oil, hemp oil, macadamia oil, and convergent olive oil. And you can cook with olive oil but only tomato sauces and things like that, things that are not high-peat, sesame oil, tahini is great as well, great fat, sesame seeds kind of paste while in oil, those are flavorful oils, they're not main oils, but you wanna avoid the traditional oils, all the seed oils like canola oil, partially hydrogenated oils, margarine, peanut oil, soybean oil, sunflower oil, safflower oil, trans fats, vegetable oil, vegetable shortening, all that stuff, that. What about veggies? What should you eat? Well, you wanna stick with lots of other veggie veggies or arduous chokes, organic if you can. I use the Dirty Dozen guide from the environmental working group, ewg.org, tell you which are the clean 15, meaning you can eat them when they're not organic or the Dirty Dozen, which you definitely not eat if they're not organic, but I love asparagus, arduous chokes, avocado, bean sprouts, broccoli, Brussels sprouts, cabbage, cauliflower, celery, cucumber, eggplant, garlic, ginger, hearts of palm, kohlrabi, leeky greens, mushrooms of all kinds, onions, peppers, radicchio, radish, rutabagas, all that kind of stuff. Steve Weed is great, lots of minerals, shallots, summer squash, tomatoes, turnips, zucchini, list goes on, we have all in there. You can have some things like sweet potatoes, like the Japanese purple sweet potatoes, winter squash, carrots, pumpkin, all that's fine. I mean, carrots are fine because unless you're doing carrot juice or that's a problem, but basically try to limit it to like one serving, which is like half a cup a day. What you should be avoiding is corn and white potatoes, mostly, little, you know, some of the little thingling potatoes or the proving potatoes, purple potatoes, which can be fine. What about dairy? You can eat pastures, butter or ghee, but I encourage you to get all dairy, including sheep and goat, which are mostly fine for people, but I encourage you to get all other dairy. And if you're having, I encourage you to have, make sure it's grass fed or originally raised. What about beans? Well, you can have green beans, you can have green peas, you can have non-jimo or organic soy, just tofu or tempeh, you can have snap beans, you can have snow peas, but otherwise, definitely no beans. What about grains? No grains at all. So even healthy grains, quinoa, buckwheat, things like that, I encourage you to get off all that. Why? Cause it just shuts down the insulin response, helps you lose weight, reduce inflammation. Not that these are necessarily all bad, but eventually you can add them back. But basically get rid of all the other, all grains, wheat, barley, rye, rice, amaranth, militef, oats, everything, get rid of it. Fruit, fruit can be okay, but small amounts, non-hygglycemic fruit. So organic blackberries, blueberries, cranberries, kiwi, lemons, limes, raspberries, all that's fine. Not too much, right? You don't even need like, you know, two pounds of blueberries, but you can have a top, top of the day. Want to get rid of all the other fruit, all the hyglycemic fruit like bananas, pineapple, melons, cherries, grapes, those are the worst. Even fruits that, fruits that you think, you know, maybe good for you are active, good for you, right? Whether it's, you know, peaches, pears, nectarines, cherries, for example, but you don't want to eat them while you're on the 10-day detox. You want to really shut down the blood sugar and some response. What about sugar sweeteners? Sorry, none. You can sometimes have a little monk fruit or CVF, you have in the shake, we have, but generally tend to avoid all that stuff. Also, just get rid of all the other artificial sweeteners, all the sugar, all that stuff. If you have to ask, the answer is no. Basically, basically. Then what should you be drinking? Well, lots of water, herbal tea, green tea. Let's go to the caffeine, that's okay. Little green tea is fine. You know, I'll be getting off coffee, sparkling water, mineral water, all that stuff. We should avoid alcohol, coffee, bottled water, some plastic soda, obviously, sugar beverages. Basically, that's the program. So if you eat that way for 10 days, if you use those simple habits, your body's going to totally transform and you're going to see just how food is impacting your health, which is something most people don't have a clue about. And that's why I love this so much. Now, after the program, it's really important if you do it for 10 days or 21 days or 10 weeks or 10 months, you have to be smart about getting off it or you can get into big trouble. Because when you go off of foods that are inflammatory, foods that are allergic to, and then you reintroduce them, you can get a lot worse symptoms. Let's say you had migraines before and then they're gone. Wow, you're going to get a doozy of a migraine or let's say you had gut issues before, you're going to get a real problem. Let's say you had sinus congestion from eating dairy and then you eat it. Again, you might get a sinus infection. So you really have to be smart. So if you're feeling great and you want to continue and let's say you have a lot of weight to lose, let's say you have an autoimmune disease, let's say you feel like you're feeling great, you want to continue, no problem. You continue it, continue to do it. You can do it for another 10 days, you can do it for another 10 months, it's fine. It's totally safe to eat. It's pretty much how you eat most of the time with occasion, grains and beans. Also prioritize sleep and obviously your fasting window, not eating your core bed. And then eventually people can transition slowly to the peag and diet, which incorporates a lot of the principles of the 10 day detox diet, but it gets you more flexibility in your diet. You can add some gluten free grains, you can add some grass fed dairy or sheep or goat. Maybe you want to do it most of the time, but occasionally I've got the wine or dessert occasionally, all that's fine. Remember when you're adding things back, you want to do it smartly. And in the 10 day detox book, we'll put in the show notes, you have to add one thing at a time. So if you're adding back gluten, just do that for three days. Don't have a pizza which has gluten and dairy, you won't know it's affecting if you feel bad. You want to know, so give yourself three days and then pick the next food. So start with gluten and dairy, then grains, other grains and whatever. You're gonna see slowly add foods back and you'll see how you feel. And that's your best barometer. The smartest doctor in the room is your own body and that's what you want to focus on. So congratulations. Hopefully you're gonna do this. Think radiation advance. You're gonna take the first steps toward optimal health, kind of hard. Sometimes they kind of know what to think or feel, but I always say, don't listen to me. Listen to your body. It's the smartest doctor in the room. Try this, see what happens. It doesn't work, 10 days, who cares, right? If it works, you have the answer and the key to unlock some of your health. If you love this podcast, please share it with someone else you think would also enjoy it. You can find me on all social media channels at Dr. Mark Hyman. Please reach out, I'd love to hear your comments and questions. Don't forget to rate, review and subscribe to the Dr. Hyman show wherever you get your podcasts. And don't forget to check out my YouTube channel at Dr. Mark Hyman for video versions of this podcast and more. Thank you so much again for tuning in. We'll see you next time on the Dr. Hyman show. This podcast is separate from my clinical practice at the Ultra Wellness Center. My work at Cleveland Clinic and Function Health where I am Chief Medical Officer. This podcast represents my opinions and my guest's opinions. Neither myself nor the podcast endorses the views or statements of my guests. This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. This podcast is provided with the understanding that it does not constitute medical or other professional advice or services. If you're looking for help in your journey, please seek out a qualified medical practitioner. And if you're looking for a functional medicine practitioner, visit my clinic, the Ultra Wellness Center at ultrawellnesscenter.com and request to become a patient. It's important to have someone in your corner who is a trained licensed healthcare practitioner and can help you make changes, especially when it comes to your health. This podcast is free as part of my mission to bring practical ways of improving health to the public. So I'd like to express gratitude to sponsors that made today's podcast possible. Thanks so much again for listening.