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David Sinclair

Mentioned in 8 analyzed podcast episodes across 7 shows

A Harvard scientist and co-founder of Life Biosciences who is recognized as a leading researcher in longevity and age reversal. He is known for his work on Yamanaka factors reprogramming and de-aging techniques, as well as his research on NAD/NMN supplements. His foundational work in cellular regeneration has made him a frequent reference point in discussions about reversing aging and developing new longevity therapies.

Episode Appearances

Modern Wisdom

Modern Wisdom · Apr 13, 2026

#1084 - David Friedberg - Everything You Know is About to Collapse

Longevity scientist with company in clinical trials for epigenetic reprogramming therapies

AI Commoditization and DecentralizationFusion Energy and Near-Zero Energy CostsEpigenetic Reprogramming and Age Reversal
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Moonshots with Peter Diamandis

Moonshots with Peter Diamandis · Mar 17, 2026

Elon Musk: Optimus 3 Is Coming, Recursive Self-Improvement Is Already Here, and the Singularity | #239

Mentioned for ER100 partial epigenetic reprogramming trials that could eliminate back pain

Recursive Self-Improvement in AIArtificial General Intelligence TimelineOptimus 3 Robot Production
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All-In with Chamath, Jason, Sacks & Friedberg

All-In with Chamath, Jason, Sacks & Friedberg · Feb 28, 2026

Software Stocks Implode, Claude's Hit List, State of the Union Reactions, Trump's Tariff Pivot

Harvard scientist and Life Biosciences co-founder leading first human Yamanaka factors trials

AI disruption of software stocksAnthropic Claude market impactSaaS business model obsolescence
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Huberman Lab

Huberman Lab · Feb 23, 2026

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Researcher known for promoting NAD/NMN longevity supplements

Parabiosis experimentsYoung blood factorsOrgan-specific aging
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LONGEVITY with Nathalie Niddam

LONGEVITY with Nathalie Niddam · Feb 13, 2026

#412: From Anti-Aging to Age Reversal: The Exosome & Copper Peptide Breakthrough For Younger Skin With Debbi Barber and Dr. Jordan Plews

Researcher whose de-aging work (three-factor reprogramming) is referenced as foundational to future regenerative therapies

Exosome sourcing and biological age of stem cellsStem cell exhaustion and agingCopper peptides (GHK-CU) and regenerative signaling
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The Herd with Colin Cowherd

The Herd with Colin Cowherd · Feb 11, 2026

3 & Out - Ken Rideout's story, Will Lamar crash out, Could McDonald call offensive plays

Longevity scientist at Harvard; author of 'Lifespan'; represented by Rideout's management company

Addiction Recovery and Athletic PerformanceUltra-Marathon Training and Endurance SportsWall Street Finance Culture and Drug Use
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Moonshots with Peter Diamandis

Moonshots with Peter Diamandis · Jan 6, 2026

Elon Musk on AGI Timeline, US vs China, Job Markets, Clean Energy & Humanoid Robots | 220

Artificial General Intelligence TimelineUniversal High Income ImplementationSpace-Based Data Centers
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The Last Invention

The Last Invention · Nov 20, 2025

EP 8: The Accelerationists

Effective AccelerationismAI Safety vs AI ProgressExistential Risk Portfolio Management
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