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Dr. Gabrielle Lyon

Mentioned in 18 analyzed podcast episodes across 9 shows

Board-certified physician and founder of the Institute for Muscle-Centric Medicine, known for pioneering a muscle-based approach to longevity and metabolic health. She hosts The Dr. Gabrielle Lyon Show and is the author of Forever Strong and The Forever Strong Playbook, which translate muscle-centric science into practical nutrition and lifestyle guidance. Frequently featured as an expert guest across health and wellness podcasts, she advocates for viewing muscle as a critical organ for preventing disease and optimizing aging.

Episode Appearances

The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Apr 21, 2026

GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra

Podcast host and co-founder of telemedicine weight management clinic, discussing GLP-1s and muscle preservation

GLP-1 medications (semaglutide, tirzepatide, retatrutide) for weight loss and diabetesMuscle preservation and body recomposition during weight lossResistance training protocols for GLP-1 patients
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Apr 14, 2026

Dominique Sachse on Aging Well, HRT, and Building Muscle After 50

Host conducting interview on aging, HRT, muscle building, and wellness topics

Hormone Replacement Therapy (HRT) for midlife and aging womenBuilding and maintaining muscle mass after 50Sleep optimization and recovery protocols
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Apr 7, 2026

The Truth about Saturated Fat, Omega-3 Fatty Acids and Total Mortality | Dr. Tom Brenna

Podcast host conducting in-depth discussion on dietary guidelines, saturated fat science, and nutrition policy implications

Saturated Fat Dietary Guidelines and Scientific JustificationTrans Fats vs. Saturated Fats in Historical Nutrition ResearchOmega-3 and Omega-6 Fatty Acid Metabolism and Ratio Balance
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Mar 31, 2026

GLP-1 Drugs & Bariatric Surgery Explained by a Top Obesity Researcher | Dr. David Allison

Podcast host conducting interview and discussing muscle, longevity, and nutrition science

GLP-1 Agonists and Anti-Obesity MedicationsBariatric Surgery Effectiveness and OutcomesDietary Guidelines and Nutritional Epidemiology
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Mar 24, 2026

Dr. Tommy Wood: Can Cognitive Decline Be Reversed?

Podcast host interviewing Dr. Wood on cognitive decline and brain aging

Alzheimer's Disease Prevention and ReversalBrain Plasticity and NeuroplasticityCognitive Decline and Dementia Risk Factors
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Makes Sense - with Dr. JC Doornick

Makes Sense - with Dr. JC Doornick · Feb 27, 2026

Metabolic Synchronization - The Secret to High Performance - Episode 148

Cited as thought leader emphasizing muscle as the organ for longevity and metabolic health in muscle-centric medicine

Metabolic Psychiatry and Brain Energy MetabolismInsulin Resistance and Mental HealthMitochondrial Dysfunction and Mood Disorders
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Feb 10, 2026

How to Eat for Strength, Metabolism, and Longevity

Host; physician and nutrition expert who advocates muscle-centric health model and root cause medicine

Protein Metabolism and Optimal IntakeResistance Training Intensity and HypertrophyBody Composition and Fat Loss Strategies
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The Jamie Kern Lima Show

The Jamie Kern Lima Show · Feb 10, 2026

#1 Secret to Aging Well Pt 2 w/Dr. Gabrielle Lyon: New Keys to Optimize Weight, Health & Longevity: Exactly How to Eat & Move

Board-certified physician and leading voice in muscle-centric medicine; author of Forever Strong and The Forever Strong Playbook

GLP-1 medications and weight loss managementSkeletal muscle as endocrine organ and metabolic sinkProtein optimization and dietary requirements
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Feb 3, 2026

Protein First: How the New Dietary Guidelines Shift Nutrition

Host of The Dr. Gabrielle Lyon Show; physician and nutrition expert; authored Forever Strong Playbook implementing new guidelines

Dietary Guidelines 2025 Protein RecommendationsRandomized Controlled Trials vs Epidemiological Evidence in NutritionAnimal vs Plant-Based Protein Bioavailability
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The Jamie Kern Lima Show

The Jamie Kern Lima Show · Jan 29, 2026

#1 Secret to Aging Well w/Dr. Gabrielle Lyon! Get Fit, Prevent Disease & Future-Proof Your Body

Board-certified physician and founder of Institute for Muscle-Centric Medicine; primary expert discussing muscle-based longevity science

Skeletal Muscle as Organ of LongevityResistance Training Protocols and FrequencyProtein Intake and Muscle Synthesis
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The Doctor's Kitchen Podcast

The Doctor's Kitchen Podcast · Jan 28, 2026

#333 Why Muscle Is the Organ of Longevity with Dr Gabrielle Lyon

Physician, author of 'Forever Strong' and 'Forever Strong Playbook', founder of Muscle-Centric Medicine Movement; primary guest

Muscle-centric medicine framework and muscle as endocrine organProtein metabolism and amino acid-specific biological roles (leucine, threonine, phenylalanine)Carbohydrate tolerance and glucose disposal rates in sedentary vs. active populations
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LONGEVITY with Nathalie Niddam

LONGEVITY with Nathalie Niddam · Jan 27, 2026

#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why "Healthy Sedentary" Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

Guest expert in geriatrics and nutritional sciences; advocates muscle as longevity organ and challenges sedentary health paradigm

Intramuscular Adipose Tissue and Metabolic DysfunctionMuscle as Endocrine Organ and Myokine ProductionResistance Training for Cognitive Enhancement and Brain Health
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On Purpose with Jay Shetty

On Purpose with Jay Shetty · Jan 26, 2026

Dr. Gabrielle Lyon: #1 Blueprint for Building Muscle That Will Change How You Age! (This Will Transform Your Long-Term Health!)

Physician and founder of Institute for Muscle-Centric Medicine; author of Forever Strong and The Forever Strong Playbook

Skeletal Muscle as Metabolic Control CenterProtein Timing and Dosing for Muscle SynthesisResistance Training Programming for Muscle Hypertrophy
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You Are Not Broken

You Are Not Broken · Jan 25, 2026

355. Muscle Centric Medicine

Muscle-centric medicine expert and guest; physician trained in geriatrics and nutritional sciences; author of upcoming playbook

Muscle protein synthesis and anabolic resistance in agingProtein requirements and amino acid profiles for adults over 40Body composition assessment (InBody scanning, DEXA, intramuscular adipose tissue)
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The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show · Jan 20, 2026

You Don’t Need Confidence, Just Do THIS | Leila Hormozi

Podcast host; physician in geriatrics and nutritional sciences; shares experiences with high-achieving spouse and family management

Self-belief as output vs. inputDiscomfort and anxiety managementFailure as data, not identity
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The Dr. Hyman Show

The Dr. Hyman Show · Jan 14, 2026

Muscle Is the Key to Longevity (Not Fat Loss) | Dr. Gabrielle Lyon

Board-certified physician specializing in muscle-centric medicine, geriatrics, and metabolism; author of Forever Strong Playbook

Skeletal Muscle as Longevity OrganSarcopenia Prevention and TreatmentProtein Requirements and Amino Acid Optimization
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LONGEVITY with Nathalie Niddam

LONGEVITY with Nathalie Niddam · Dec 12, 2025

#395: Brain Fog, Anger, Detox Secrets & The Truth About Diet Sodas | Unlocking LIVER Longevity With Siggi Clavien

Collaborated with Siggi on protocol linking muscle preservation and liver health as dual longevity factors

Fatty Liver Disease (NAFLD/NASH)Liver Detoxification Phases (Phase 1, 2, 3)Brain-Liver Axis and Cognitive Function
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The Peter Attia Drive

The Peter Attia Drive · Sep 22, 2025

#365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere

Fellowship-trained physician in geriatrics and nutritional sciences; founder of muscle-centric medicine; author of 'Forever Strong'

Resistance training participation gap and barriers to entryUnilateral vs. bilateral lower body training for adultsProtein requirements across age, sex, and activity levels
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