Podcasts · Health & Fitness
The Peter Attia Drive
261 episodes · 20 with AI analysis
Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.
AI Intelligence · across all analyzed episodes
People · top 20
Companies · top 20
Harvard Business School×3FDA×3Buck Institute for Research on Aging×2Duke University×2McDonald's×2Abbott×2UK Biobank×2UCSF×2Stanford University×2CDC×2University of Michigan×2American Cancer SocietyPrinceton UniversityHay HouseFrito-LayGlaxoSmithKline (GSK)SumoUniversity of OtagoBoston BruinsNeuralink
Topics · top 10
Age-stratified health priorities across life decadesFour horsemen of chronic disease (cardiovascular, cancer, neurodegenerative, metabolic)Dementia prevention strategies and genetic risk factorsDEXA scan screening intervals and interpretationBehavior change and habit formation in health routinesStability training and injury resilienceHigh protein diets and mTOR activationNon-nutritive sweeteners and diet soda evaluationWearable metrics and consumer health data utilityDisease screening and early detection strategies
Analyzed Episodes
Mar 23, 2026
#385 - AMA #82: Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more
Age-stratified health priorities across life decadesFour horsemen of chronic disease (cardiovascular, cancer, neurodegenerative, metabolic)Dementia prevention strategies and genetic risk factors
View AnalysisApr 6, 2026
#386 - Aging clocks—what they measure, how they work, and their clinical and real-world relevance
Epigenetic clocks and DNA methylation as aging biomarkersBiological age vs. chronological age vs. pace of agingClinical trial design for longevity interventions
View AnalysisApr 13, 2026
#387 - AMA #83: Peptides—evaluating the science, safety, and hype in a rapidly growing field
Peptide mechanism of action evaluation frameworkFDA-approved vs. gray-market peptide therapeuticsPeptide efficacy and safety data assessment
View AnalysisApr 20, 2026
#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives
PSA velocity and longitudinal PSA monitoringPSA density and MRI-guided screeningTransperineal vs. transrectal prostate biopsy techniques
View AnalysisMay 18, 2026
#392 - Genetic testing: when it's valuable, how to choose the right test, and what to do with the results
BRCA mutations and hereditary cancer screeningAPOE4 and Alzheimer's disease risk stratificationPharmacogenetics and drug metabolism (CYP2C19, HLA-B*5801)
View AnalysisMay 4, 2026
#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration
Family Health History AssessmentGenetic Testing vs. Family HistoryCardiovascular Disease Prevention
View AnalysisMay 11, 2026
#391 ‒ Colorectal cancer screening: importance of early screening, colonoscopy as a screening and preventive tool, and how to build a personalized strategy
Colorectal cancer screening protocols and intervalsColonoscopy procedure quality and preparationEarly-onset colorectal cancer epidemiology
View AnalysisApr 27, 2026
#389 - Thinking scientifically: why it's hard, why it matters, and a practical toolkit
Scientific thinking and epistemologyCognitive biases and social identity in belief formationEvaluating expert credibility and trustworthiness
View AnalysisJun 23, 2025
#354 – What the dying can teach us about living well: lessons on life and reflections on mortality | BJ Miller, M.D. and Bridget Sumser, L.C.S.W.
Palliative Care vs. Hospice Care DistinctionsAdvance Directives and Medical Decision-MakingDelirium in End-of-Life Care
View AnalysisJun 30, 2025
#355 – Skincare strategies, the science of facial aging, and cosmetic-intervention guidance | Tanuj Nakra, M.D. & Suzan Obagi, M.D.
Facial bone loss and mandibular retrusion in agingHormonal influences on facial fat distribution and skin integrityMineral vs. chemical sunscreen efficacy and safety
View AnalysisJul 7, 2025
Navigating bone health: early life influences and advanced strategies for improvement and injury prevention (#214 rebroadcast)
Bone Mineral Density (BMD) screening and DEXA scan interpretation (T-scores and Z-scores)Hip and pelvic fracture mortality risk in aging populationsMenopause and estrogen withdrawal effects on bone remodeling
View AnalysisJul 14, 2025
#356 - AMA #73: Preserving brain health, optimizing exercise programming, improving body composition, and more
Dementia and Alzheimer's disease risk factorsModifiable vs. non-modifiable cognitive decline risk factorsApoE4 genotype and genetic predisposition to dementia
View AnalysisJul 21, 2025
#357 ‒ A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D.
mTOR signaling and rapamycin dosing strategiesBiological aging clocks and mortality predictionAlpha-ketoglutarate supplementation and lifespan extension
View AnalysisJan 5, 2026
#378 ‒ Women's health and performance: how training, nutrition, and hormones interact across life stages | Abbie Smith-Ryan, Ph.D.
Bone health and osteoporosis prevention in childhood and adolescenceMenstrual cycle periodization and training/nutrition strategies across follicular and luteal phasesBody composition measurement and recomposition strategies in midlife women
View AnalysisJul 28, 2025
#358 ‒ Peter's takeaways on navigating HRT, rejuvenating the face, understanding the biology of aging, optimizing fertility, and learning to live well from the dying | Quarterly Podcast Summary #6
Male fertility optimization and sperm health assessmentFemale fertility and conception biologyWomen's sexual health and menopause management
View AnalysisAug 4, 2025
#359 ‒ How metabolic and immune system dysfunction drive the aging process, the role of NAD, promising interventions, aging clocks, and more | Eric Verdin, M.D.
NAD metabolism and CD38 inhibitionEpigenetic aging clocks and their limitationsThymic involution and immune aging
View AnalysisAug 11, 2025
#360 ‒ How to change your habits: why they form and how to build or break them | Charles Duhigg, M.B.A
Habit Formation Science: Cue-Routine-Reward LoopPositive vs. Negative Reinforcement EffectivenessEnvironmental Design for Behavior Change
View AnalysisAug 18, 2025
#361 - AMA #74: Sugar and sugar substitutes: weight control, metabolic effects, and health trade-offs
Sugar metabolism and appetite hormonesFructose versus glucose metabolic effectsNon-nutritive sweeteners (saccharin, aspartame, sucralose)
View AnalysisSep 1, 2025
Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D. (#287 rebroadcast)
Disc herniation mechanics and delamination progressionFacet joint loading and osteoarthritis cascadeSpinal stenosis and nerve root compression assessment
View AnalysisSep 8, 2025
#363 ‒ A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D.
Brain-Computer Interfaces (BCIs) for Speech RestorationAwake Brain Surgery and Intraoperative MappingGlioblastoma Treatment and Genomic Profiling
View Analysis